The Popkin Method
The Popkin Method
TopHealth Media
You’re not crazy. Your care is just fragmented. Most people bounce between specialists, apps, and online “biohacks” without ever getting real answers.The Popkin Method is here to change that - with real, physician-led medicine that integrates the best of internal and functional approaches into one clear, personalized care.Hosted by Matthew C. Popkin, M.D., a board-certified internist with surgical training and functional medicine expertise - this podcast explores how to reconnect the dots between your symptoms, labs, lifestyle, and deeper health goals.Whether you're battling fatigue, inflammation, hormones, weight, or aging - this show delivers clinical insight, clarity, and next steps… with none of the hype.Real medicine. Real results. Real transformation.
Beyond Peptides: Building a Lasting Weight Loss Foundation with the Popkin Method
Welcome to The Popkin Method, where we cut through the noise of miracle weight loss solutions and trendy shortcuts dominating social media and advertising today. In this episode, Dr. Matthew C. Popkin takes a deep, clinical dive into GLP-1-based therapies like semaglutide and tirzepatide, some of the most talked-about tools in modern medicine. But here’s the catch: these medications aren’t magic fixes. Instead, Dr. Matthew C. Popkin unpacks the importance of a comprehensive, sequenced approac...
May 29
55 min
Demystifying Fatty Liver Disease: The Four-Phase Popkin Method for Sustainable Metabolic Health
Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the most misunderstood, yet critical, obstacles to lasting weight loss and wellness: fatty liver disease. Most people think of it as just a byproduct of poor diet or being overweight, but as you’ll learn today, fatty liver is actually a hidden metabolic bottleneck that could be sabotaging your best efforts to get healthy. If you’ve ever felt inexplicably stuck with your weight, tired for no clear reaso...
May 20
1 hr 13 min
Unlocking the Cellular Secrets of Aging: How NAD Fuels Longevity from the Inside Out
Welcome back to The Popkin Method! In this episode, Dr. Matthew C. Popkin takes us beyond the surface of anti-aging, exploring the science of aging from the inside out. We’re all familiar with visible signs like wrinkles and graying hair, but what really drives aging happens deep within our cells. Dr. Matthew C. Popkin uncovers the critical role of mitochondrial function and the powerful molecule NAD, revealing how their decline accelerates aging and chronic disease. You’ll learn why energy p...
Apr 30
53 min
Building Sustainable Care Plans: The Popkin Method Approach to Lasting Health
Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the biggest challenges in modern healthcare: making care plans that truly stick. Most people don’t fail their health plans; the plans fail them, often because they’re too complex, reactive, or fragmented. Instead of bouncing between specialists and juggling conflicting advice, Dr. Matthew C. Popkin shares his approach for building a sustainable, integrated care strategy that focuses on foundational lif...
Apr 18
38 min
Demystifying Hormone Optimization Therapy for Men and Women with the Popkin Method
Welcome to another episode of The Popkin Method, where we’re passionate about restoring physiology, preserving lean muscle mass, stabilizing your metabolism, and building long-term resilience from the inside out. This week, Dr. Popkin tackles one of the most misunderstood and sought after topics in modern medicine: hormone optimization therapy. You’ll hear why hormone issues aren’t just a women’s health concern, but instead affect both men and women, often creeping in silently and earlier tha...
Mar 27
52 min
Reversing Chronic Inflammation: The Popkin Method’s Three-Phase Approach for Better Health
Welcome back to The Popkin Method! In this episode, host Dr. Matthew C. Popkin dives deep into one of the most important yet misunderstood topics in modern health: whole body systemic inflammation. You’ll discover what chronic inflammation really is, how it subtly wreaks havoc on everything from metabolism and hormones to mood, gut health, and even cancer risk, and, most importantly, how to reverse it using the core principles of The Popkin Method. You’ll hear a heartfelt public service annou...
Mar 13
50 min
Blood Sugar Chaos: How Stabilizing Glucose Unlocks Lasting Energy, Gut Health, and Calm
Welcome back to The Popkin Method! In this episode, Dr. Matthew C. Popkin explores the real reasons behind energy crashes, anxiety, cravings, and stubborn gut issues, the hidden chaos of blood sugar instability. Most of us only think about blood sugar in the context of diabetes, but as Dr. Matthew C. Popkin explains, glucose swings can impact anyone, showing up as symptoms long before any lab test does. You’ll hear how stress, diet, poor sleep, and even restrictive eating plans can send your ...
Feb 26
1 hr
Healing an Overwhelmed Gut: Stress, Food, and the Popkin Method Approach
Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles a myth that so many people struggle with: the belief that their gut is broken for good. But is it really? Or is your gut just overwhelmed and crying out for support? You’ll hear Dr. Matthew C. Popkin break down the real science of gut health, from the basics of digestion and absorption, to the deep connections between your gut, immune system, hormones, and brain. He digs into why symptoms like bloating, const...
Feb 10
36 min
Why Clean Eating Alone Isn’t Enough: Personalizing Nutrition for Metabolic Health and Muscle Gain
Welcome to The Popkin Method Podcast! In this episode, host Dr. Matthew C. Popkin tackles one of the most common and frustrating health mysteries: why "clean eating" sometimes just doesn’t deliver the energy or results we expect. If you’ve ever followed popular nutrition advice, cut out processed foods, or chased the latest diet trend only to feel tired, bloated, or stuck, you’re not alone. Today, he breaks down why one-size-fits-all nutrition can miss the mark and explains what actually work...
Feb 2
52 min
Personalized Peptides, Hormones, and Stem Cells: The Popkin Method for Regenerative Wellness
Welcome to The Popkin Method, where real medicine meets real results. In this episode, Dr. Matthew C. Popkin tackles the buzz surrounding regenerative medicine; think peptides, hormone replacement therapy, stem cells, and exosomes. These cutting-edge therapies are making headlines everywhere, from social media to specialty clinics, but are they really a magic bullet for health and vitality? Dr. Popkin pulls back the curtain on what’s driving all this hype and offers a no-nonsense look at how ...
Dec 30, 2025
50 min
Load more