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September 8, 2019
There's been a lot of talk about the need for our healthcare system to shift away from volume and fee-for-service, where you pay by appointment, procedure, etc, to value-based care, where you pay for both quality and outcomes—essentially, good health. But there's also been a real dearth of seeing how that might work in action, or concrete models for how to implement it at scale. In this episode, CEO of Blue Cross Blue Shield North Carolina Patrick Conway dives deep into how exactly we can make the move towards this kind of healthcare a reality, in conversation with a16z's General Partner Jorge Conde, Venkat Mocherla and Hanne Tidnam. Conway—also a pediatrician, and formerly Deputy Administrator at the Centers for Medicare and Medicaid Services (CMS) and Director of the Center for Medicare and Medicaid Innovation (CMMI)—gets into what value-based care really means; different ideas for how payors can implement the shift away from fee-for-service and volume-based care towards outcomes; as well as the critical role social determinants (food insecurity, transportation, and more) play in our health—and how tech can be a driver of change. And finally, Conway shares thoughtful analysis from an insider’s point of view from the Hill on how to actually effect change in policy and regulation in healthcare to move the entire system in this direction.
September 6, 2019
with @bhorowitz @shakasenghor @diishanimira @therealritabee Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology platforms -- and mindsets -- for everybody and anybody who has the desire, the talent, and the hustle to do great things. Read more about it here.  Episode #3, "The Hustler's Guide to the Hair Business" features Diishan Imira, CEO and co-founder of Mayvenn, a technology company re-shaping salon retail distribution; Sherita (SherriAnn) Cole, who uses Mayvenn for her hair stylist business -- both interviewed by Ben Horowitz and Shaka Senghor. "Can you fit in this box? You always have to fit in a box, and for the first time in a life, it's like I didn't have to fit in anyone's box, and I could create my own box -- maybe it's not a box, maybe it’s a star shape." music: Chris Lyons
September 6, 2019
with @bhorowitz @shakasenghor ram @earnin & vaughn ferguson Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology platforms — and mindsets — for everybody and anybody who has the desire, the talent, and the hustle to do great things. Read more about it here. Episode #2, “The Hustler’s Guide to Getting Paid” (early, but actually, on time) features Ram Palianappan, CEO and founder of Earnin, which allows workers to access their pay instantly with no fees or interest; Vaughn Ferguson, who uses Earnin to avoid overdraft fees or payday loans -- both interviewed by Ben Horowitz and Shaka Senghor. "Just knowing that more people are really using these things that are out there, to their advantage and not their detriment." music: Chris Lyons
September 6, 2019
with @bhorowitz @shakasenghor @8ennett & sherie james Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology platforms -- and mindsets -- for everybody and anybody who has the desire, the talent, and the hustle to do great things. Read more about it here.  Episode #1, "The Hustler's Guide to Preschool" features Chris Bennett, CEO and co-founder of Wonderschool, a network of modern early education programs that helps both parents and teachers to start and manage early childhood education centers; Sherie James, who uses Wonderschool to operate her own in-home preschool and daycare -- both interviewed by Ben Horowitz and Shaka Senghor, live at the 25th Anniversary Essence Festival Global Economic Black Forum in New Orleans. music: Chris Lyons
September 6, 2019
We're excited to introduce a new podcast series hosted by a16z co-founder Ben Horowitz and Shaka Senghor, a leading voice in criminal justice reform and bestselling author. The series is called “Hustlin’ Tech” and so far, there are three episodes to follow, which you can find in this feed: #1 The Hustler’s Guide to Preschool #2 The Hustler’s Guide to Getting Paid #3 The Hustler’s Guide to the Hair Business You can read more about the what and the why of this new series -- and sign up to be notified about future episodes -- at: a16z.com/hustlin
September 2, 2019
"You cannot be IN it... and not be OF it." Dapper Dan a.k.a. Daniel Day shares his remarkable history and story of defining an era of fashion and cultural influence in this special episode of the a16z Podcast -- based on his conversation (also available as video here) with Ben Horowitz around his memoir, Made in Harlem. Dapper Dan pioneered high-end streetwear in the early 1980s, remixing luxury brand logos into his own designs for gangsters, athletes, and musicians, dressing cultural icons from Salt-N-Pepa and Eric B. & Rakim to Beyoncé and Jay-Z along the way. Going on to define an era, his work has been featured in exhibitions at the Museum of Modern Art, the Met, The Smithsonian, and more. But he began as a hungry, fast learner in Harlem who became a gambler; spent a brief stint in a foreign jail where he nourished himself with reading; and then studied the market to build his fashion business, trendsetting the concepts of logomania and later, influencer marketing. Today, Dapper Dan has a unique partnership with Gucci and reopened his boutique in 2017. From "the struggle" when not given the privileges and opportunities that others have to the struggle of building and then losing and then reinventing oneself again and again, this special episode offers inspiration for all kinds of makers -- including the power of "studying the game"; the power of listening to your customers (not in the cliché way!); and the power of cultural influence... and voice. photo credits: Alain McLaughlin
August 29, 2019
What can we learn from the history of the internet for the future of crypto? In this episode of the a16z Podcast, general partner Katie Haun interviews a16z co-founder Marc Andreessen -- and co-founder of Netscape, which helped popularize and mainstream the internet for many -- and who also penned "Why Software is Eating the World" (in the Wall Street Journal in 2011) and "Why Bitcoin Matters" (in the New York Times in 2014). This episode is based on a fireside chat between Katie and Marc at our inaugural Crypto Regulatory Summit, which brings together leading crypto experts and builders, other technologists, academics, industry executives, and government officials -- along with forward-thinking regulators -- to foster collaboration and the exchange of ideas around this important emerging industry. Why is crypto an important evolution (or revolution) of the internet? What can entrepreneurs, corporations, and policymakers learn from the beginnings of the browser, e-commerce, and other examples about how emerging technologies move forward?
August 29, 2019
with @ldhawke and @stevesi The government wants to get onto the cloud! But how do they assess the levels of risk in adopting specific cloud products, and which "cloud service providers" (aka "CSPs") to work with? That's where FedRAMP -- the Federal Risk and Authorization Management Program -- comes in. And enterprise SaaS companies need to pay attention, since it will be a requirement for selling to the U.S. government, which is one of the biggest buyers of tech. Not just that, but even state governments and private/public companies may seek FedRAMP certification because they either work with the federal government or are just seeking standards. How similar or different is FedRAMP to other types of certification, authorization, and compliance (such as ISO, SOC-2, GDPR, even HIPAA); and what does it mean for a startup to go through organizationally, culturally? Is it like a check-the-box policy thing, is it like getting a driver's license... or what? One thing's for sure: It's an opportunity for enterprise SaaS startups, and the government is trying to help companies through the process. What are the steps to certification? What are some acronyms and terms to be aware of? When and how should you bring a consultant, advisor, or third-party auditor into the process? How long does it take, really? And how does it affect your sales team? Most importantly, what is the best strategy for moving forward? (Hint: start with a customer). Lisa Hawke, VP of Security and Compliance at Everlaw, an a16z company, shares her expertise and their experience in navigating all this, as well as the resources below, in this episode of the a16z Podcast hosted by board partner Steven Sinofsky. (The two were also previously on another episode sharing everything startups need to know about GDPR.) For links mentioned in this episode and other resources, see: https://a16z.com/2019/08/28/fedramp-why-what-how-for-startups/
August 25, 2019
with @illscience and @smc90 This is episode #7 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends. This week we cover, with the following a16z experts: * Apple releasing a credit card, and what it means beyond the card features itself, what it means for consumer credit (and recession risks), and the financial ecosystem overall -- with new a16z fintech general partner Anish Acharya; * BEC frauds and scams indictment and the FBI bringing a massive federal grand jury indictment, one of the biggest of its kind, and what it means and how to prevent this type of cyber fraud -- with a16z operating partner for security Joel de la Garza; ...hosted by Sonal Chokshi. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
August 18, 2019
Back in 2011, a16z cofounder Marc Andreessen first made the bold claim that software would eat the world. In this episode (originally recorded as part of an event at a16z), Andreesseen and a16z general partner on the bio fund Jorge Conde (@JorgeCondeBio) take a look back at that thesis, and think about where we are now, nearly a decade later—how software has delivered on that promise… and most of all, where it is yet to come. In the wide-ranging conversation, the two partners discuss everything from the translatable learnings of software’s transformation of the music and automotive industries, to how software will now eat healthcare (including what exactly changed in the fields of bio and computer science to make Marc eat his own words!). *** The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
August 12, 2019
with @julesyoo @smc90 This is episode #6 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we cover, with the following a16z experts: * health claims, insurance & big tech, and healthcare data liquidity -- with a16z bio partner Julie Yoo; * Capital One data breach, cloud security, and corporate hacks -- with a16z operating partner for security Joel de la Garza; ...hosted by Sonal Chokshi.
August 12, 2019
with @astrange @jeff_jordan and @smc90 This is episode #5 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we cover, with the following a16z experts: * Federal Reserve real-time payment and settlement service FedNow, the U.S. payments rail, and fintech -- with a16z general partner Angela Strange; * Barney's bankruptcy, the "death of retail", and ecommerce -- with a16z general partner Jeff Jordan; ...hosted by Sonal Chokshi.
August 4, 2019
with @jorgecondebio @vijaypande and @smc90 This is episode #4 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we do a short but deep dive on the opioid crisis, given recent data around where and who was behind the manufacturing and distribution of specific opioids: * How do opioids work, why these drugs? * Who's to blame? * What are other directions for managing pain -- and where could tech come in, even with the broader social, cultural, and structural context involved? Our a16z experts in this episode are a16z bio general partners Jorge Conde and Vijay Pande, in conversation with host Sonal Chokshi.
August 4, 2019
with @andrewchen @dcoolican and @smc90 This is episode #3 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we do a short but deep dive on esports, given recent news of the inaugural Fortnite World Cup champion, and how this all fits into the broader trends in gaming, social networks, and the future of entertainment. Our a16z experts in this episode are general partner Andrew Chen and investing team partner D'Arcy Coolican, both of the consumer vertical, in conversation with host Sonal Chokshi.
July 28, 2019
with @martin_casado @jorgeconde @jayrughani and @smc90 This is episode #2 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views on these trends as well. This week we cover, with the following a16z experts: * . mobile malware and a recent report of a new kind in the wild and security in a post-perimeter world -- with a16z general partner Martin Casado; * drug pricing given recent proposals on the table, sharing a lay of the land for why drug pricing is so damn hard, what is a medicine, and where tech comes in -- with a16z bio general partner Jorge Conde and market dev partner Jay Rughani; ...hosted by Sonal Chokshi. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.  This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
July 24, 2019
with Kurt House (@kurtzhouse), John Thompson, Connie Chan (@conniechan) and Hanne Tidnam (@omnivorousread) The exploration for and mining of certain metals has driven huge epochs of human civilization, from copper and iron to gold and diamonds. In this conversation, Kurt House, CEO and co-founder of KoBold Metals; John Thompson, professor of earth and geosciences at Cornell and longtime advisor to the mining industry; and Connie Chan, general partner for consume, talk with Hanne Tidnam about why it is that cobalt is suddenly one of the most important metals on the planet. Because this metal makes today's best batteries for phones, electric cars, and more, we have gone from little to enormous demand -- with that demand expected to only increase. This conversation covers the way technology is transforming how we find cobalt, and the mining industry as a whole. Along the way we touch on the science behind why exactly it is that cobalt is so damn good in batteries; what we know about what makes cobalt as a metal 'tick', where it's currently mined, and where it's most likely to be found; what data and knowledge used to drive mining; and what the new data sources, technologies, and techniques are today, from geophysical/ geochemical data, to agricultural information, to old boxes collected over centuries in the basements and attics of mining cos…. all of this to satisfy the incredible spike of demand for this material, as we enter a new age of battery metals.
July 21, 2019
with @vijaypande @conniechan @jpm25 and @smc90 Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? This is the first episode of the show, and this week we cover the below topics with the following experts: * Neuralink's recent news/ event/ whitepaper and the trend of brain-computer interfaces -- with a16z bio general partner Vijay Pande * TikTok video influencers and AI-driven media and commerce -- with general partner, consumer, Connie Chan * FaceApp and privacy beyond national security -- with operating partner, security, Joel de la Garza * iHeart Radio and direct listings -- with operating partner, corporate development, Jamie McGurk ...hosted by Sonal Chokshi. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation.  This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
July 19, 2019
In this final of a 3-part series (which originally aired as YouTube videos) on working with venture investors, a16z Managing Partner Scott Kupor shares best practices for working with your board as it grows from just you, your co-founders and first investor all the way through the time when you are recruiting independent board members in preparation for going public. Want to learn more? Read Scott's book "Secrets of Sand Hill Road: Venture Capital and How to Get It" (https://a16z.com/book/secrets-of-sand-hill-road/). **** The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
July 18, 2019
So you've decided raising venture capital is the best fundraising strategy for your startup. Now what? In this second of a 3-part series, a16z Managing Partner Scott Kupor shares actionable fundraising advice based on his experience of seeing thousands of startup pitches and working on all of a16z's investments. Want to learn more? Read Scott's book "Secrets of Sand Hill Road: Venture Capital and How to Get It" (https://a16z.com/book/secrets-of-sand-hill-road/). **** The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
July 17, 2019
Incentives matter. So understanding the incentives of venture capitalists will help you decide if raising money from a venture investor makes sense for your business. In this first of a 3-part series, which originally aired as YouTube videos, a16z Managing Partner Scott Kupor talks with Frank Chen about how venture capital works: how the money flows, what Limited Partners (the organizations that invest in venture capitalists) are looking for, what differentiates the top investors, and what all of this means for an entrepreneur raising money. Want to learn more? Read Scott's book "Secrets of Sand Hill Road: Venture Capital and How to Get It" (https://a16z.com/book/secrets-of-sand-hill-road/). Stay tuned for parts 2 and 3. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
July 7, 2019
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson) Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreessen Horowitz founders Marc Andreessen and Ben Horowitz. This episode was actually recorded in 2017 at our annual innovation Summit, and features technology writer Steven Johnson interviewing Ben and Marc about everything from their relationship to creative inspirations. You can find other episodes in this series at a16z.com/10.
July 7, 2019
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen) Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreessen Horowitz founders Marc Andreessen and Ben Horowitz. This episode was actually recorded in 2018 at our annual innovation Summit, and features economist Tyler Cowen interviewing Ben and Marc about everything from their partnership and how it works to talent, tech trends, and software eating culture. You can find other episodes in this series at a16z.com/10.
July 7, 2019
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), Scott Kupor (@skupor), and Sonal Chokshi (@smc90) Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreessen Horowitz founders Marc Andreessen and Ben Horowitz. This episode was actually recorded in 2016 -- on the 5-year anniversary of Marc’s Wall Street Journal op-ed on “Why software is eating the world” -- and features Sonal Chokshi and Scott Kupor interviewing Ben and Marc about what’s changed since, and how software is programming the world... in everything from simulations to distributed systems to other key computing shifts. You can find other episodes in this series at a16z.com/10.
July 7, 2019
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Michael Copeland Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreessen Horowitz founders Marc Andreessen and Ben Horowitz. This episode was actually recorded in 2014, on the 5-year anniversary of the firm, and features Michael Copeland interviewing Ben and Marc about disruption theory, as well as key traits of entrepreneurs. You can find other episodes in this series at a16z.com/10.
June 29, 2019
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Stewart Butterfield (@stewart) A lot in technology -- and venture -- happens in decades. New cycles of technology come and go, including some secular shifts; a new generation of founders matures; and so much more changes. So when Andreessen Horowitz (dubbed with the numeronym "a16z") was founded a decade ago as of this month, the tech landscape looked very different between then and now: Not only had the global economy just seen a recession, but trends like mobile and cloud and even social were just taking off. Now, 10 years later, what's changed -- not just in tech, but in profiles of entrepreneurs? And what's changed in the firm itself, given that Marc and Ben -- the Andreessen and the Horowitz -- were yet again entrepreneurs in founding the firm too? As another repeat entrepreneur from then to now, guest host Stewart Butterfield, CEO of Slack, interviews the a16z co-founders in this special episode of the a16z Podcast to commemorate our 10th anniversary. * * * The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
June 26, 2019
Two recent scientific journal papers show what's possible when CRISPR moves from cutting DNA tool to a full-fledged platform -- expanding its toolkit for medicine across R&D, therapeutics, and diagnostics: "Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration" in Nature -- by Sanne Klompe, Phuc Vo, Tyler Halpin-Healy, and Samuel Sternberg (of Columbia University) "RNA-guided DNA insertion with CRISPR-associated transposases" in Science -- by Jonathan Strecker, Alim Ladha, Zachary Gardner, Jonathan Schmid-burgk, Kira Makarova, Eugene Koonin, and Feng Zhang (of the Broad Institute) What do these two papers -- both about techniques for getting rid of the need to cut the genome to edit it -- make possible going forward, given the ongoing shift of biology becoming more like engineering? Where are we in the wave of the genome engineering "developer community" building on top of CRISPR with a constantly growing suite of programmable functionalities? a16z bio general partner Jorge Conde and bio deal team partner Andy Tran chat with Hanne Tidnam about these trends -- and these two papers -- in this short internal hallway-style conversation, part of our new a16z Journal Club series. This podcast is also part of our new a16z bio newsletter, which you can sign up for at a16z.com/subscribe
June 25, 2019
Synthetic fraud—yes, it's a thing: a new evolution of consumer fraud that’s been emerging in financial services, to the tune of $1-$2B a year. In this episode of the a16z Podcast, Naftali Harris, co-founder and CEO of Sentilink, which builds technology to detect and stop synthetic fraud, talks with a16z's Hanne Tidnam and operating partner for information security Joel de la Garza all about what this new kind of fraud is. Where did this new form of fraud come from, and why is it on the rise? Who are true victims here (hint: it's not the Joneses... or maybe it is!). And what is the fundamental security issue really at the heart of it all? The conversation covers the fascinating life cycle of this long con: how these “synthetic” identities get made, incubated, and finally busted out… and some of the wildest stories (and art of storytelling!) behind the strangest fraud rings we've seen. *** The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information. Where did this new form of fraud come from, and why is it on the rise? Who are true victims here (hint: it's not the Joneses... or maybe it is!). And what is the fundamental security issue really at the heart of it all? The conversation covers the fascinating life cycle of this long con: how these “synthetic” identities get made, incubated, and finally busted out… and some of the wildest stories (and art of storytelling!) behind the strangest fraud rings we've seen.
June 19, 2019
How have we gotten to where were are with machine learning? Where are we going? a16z Operating Partner Frank Chen and Carnegie Mellon professor Tom Mitchell first stroll down memory lane, visiting the major landmarks: the symbolic approach of the 1970s, the "principled probabalistic methods" of the 1980s, and today's deep learning phase. Then they go on to explore the frontiers of research. Along the way, they cover: - How planning systems from the 1970s and early 1980s were stymied by the "banana in the tailpipe" problem - How the relatively slow neurons in our visual cortex work together to deliver very speedy and accurate recognition - How fMRI scans of the brain reveal common neural patterns across people when they are exposed to common nouns like chair, car, knife, and so on - How the computer science community is working with social scientists (psychologists, economists, and philosophers) on building measures for fairness and transparency for machine learning models - How we want our self-driving cars to have reasonable answers to the Trolley Problem, but no one sitting for their DMV exam is ever asked how they would respond - How there were inflated expectations (and great social fears) for AI in the 1980s, and how the US concerns about Japan compare to our concerns about China today - Whether this is the best time ever for AI and ML research and what continues to fascinate and motivate Tom after decades in the field --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
June 16, 2019
with Tony Blair (@InstituteGC), Scott Kupor (@skupor), and Sonal Chokshi (@smc90) If the current pace of tech change is the 21st-century equivalent of the 19th-century Industrial Revolution — with its tremendous economic growth and lifestyle change — it means that even though it’s fundamentally empowering and enabling, there’s also lots of fears and misconceptions as well. That’s why, argues former U.K. prime minister Tony Blair (who now has an eponymous Institute for Global Change), we need to make sure that the changemakers — i.e., technologists, entrepreneurs, and quite frankly, any company that wields power — are in a structured dialogue with politicians. After all, the politician’s task, observes Blair, is “to be able to articulate to the people those changes and fit them into a policy framework that makes sense”. The concern is that if politicians don't understand new technologies, then "they'll fear it; and if they fear it, they'll try and stop it" -- and that's how we end up with pessimism and bad policy. Yet bad regulations often come from even the very best of intentions: Take for example the case of Dodd-Frank in the U.S., or more recently, GDPR in Europe -- which, ironically (but not surprisingly) served to entrench incumbent and large company interests over those of small-and-medium-sized businesses and startups. And would we have ever had the world wide web today if we hadn't had an environment of so-called "permissionless innovation", where government didn't decide up front how to regulate the internet? Could companies instead be more inclusive of stakeholders, not just shareholders, with better ESG (environment, social, governance)? Finally, how do we ensure a spirit of optimism and focusing on leading vs. lagging indicators about the future, while still being sensitive to short-term displacements, as with farmers during the Industrial Revolution? This hallway-style style episode of the a16z Podcast features Blair in conversation with Sonal Chokshi and a16z managing partner Scott Kupor -- who has a new book, just out, on Secrets of Sand Hill Road: Venture Capital and How to Get It, and also often engages with government legislators on behalf of startups. They delve into mindsets for engaging policymakers; touch briefly on topics such as autonomous cars, crypto, and education; and consider the question of how government itself and politicians too will need to change. One thing's for sure: The discussion today is global, beyond both sides of the Atlantic, given the flow of capital, people, and ideas across borders. So how do we make sure globalization works for the many... and not just for the few.  image credit: Benedict Macon-Cooney --- The views expressed here are those of the individual personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors and may not under any circumstances be relied upon when making a decision to invest in any a16z funds. PLEASE SEE MORE HERE: https://a16z.com/disclosures/
June 13, 2019
with Eric Topol (@EricTopol) and Vijay Pande (@vijaypande) Artificial intelligence is coming to the doctor’s office. In this episode, Dr. Eric Topol, cardiologist and chair of innovative medicine at Scripps Research, and a16z’s general partner on the Bio Fund Vijay Pande, have a conversation around Topol’s new book, Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. What is the impact AI will have on how your doctor engages with you? On the nature of the doctor's visit as a whole? How will AI impact not just doctor-patient interactions, but diagnosis, prevention, prediction, medical education, and everything in between? Topol and Pande discuss how AI’s capabilities for deep phenotyping will shift our thinking from population health to understanding the medical health essence of you, how the industry might respond and the challenges in integrating and introducing the technology into today’s system—and ultimately, what that the doctor’s visit of the future might look like.
June 10, 2019
Want actionable advice from a founder who has built multiple tech companies and has invested the time to be open, introspective, and transparent about lessons learned? In this episode (which originally aired as a YouTube video), a16z General Partner Andrew Chen (@@andrewchen) talks with Justin Kan (@justinkan). Justin is a repeat entrepreneur who co-founded Kiko Software (a Web 2.0 calendar that pre-dated Google Calendar by 4 years); Justin.tv (a lifecasting platform); Twitch.tv (a live streaming platform for esports, music, and other creatives now part of Amazon); Socialcam; and now Atrium, a software-powered law firm for startups. Justin reflects on his journey and shares 10 + 1 lessons he’s learned: - The paradox of choice: choosing a focus - Tradeoffs between B2B versus B2C companies - Market risk vs execution risk - Fundraising strategy: go big or stay lean? - Managing the stress of being a startup CEO (again!) - Seeking out mentors, coaches, and peers for help - Intentionally designing a culture to avoid the pitfalls of “culture eating strategy” - Things he’s still doing in his latest startup—and things he’s doing very differently - Managing higher expectations - What he’s reading and listening to - Bonus: advice he’d give his 20-year old self ***** The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
June 7, 2019
with Vijay Pande (@vijaypande) and Bharath Ramsundar Deep learning has arrived in the life sciences: every week, it seems, a new published study comes out... with code on top. In this episode, a16z General Partner Vijay Pande and Bharath Ramsundar talk about how AI/ML is unlocking the field in a new way, in a conversation around their book, Deep Learning for the Life Sciences: Applying Deep Learning to Genomics, Microscopy, Drug Discovery, and More (also co-authored with Peter Eastman and Patrick Walters. So -- why now? ML is old, bio is certainly old. What is it about deep learning's evolution that is allowing it to finally making a major impact in the life sciences? What is the practical toolkit you need, the right kinds of problems to attack, and the right questions to ask? How is the hacker ethos coming to the world of biology? And what might “open source biology” look like in the future?
June 3, 2019
with Van Jones (@VanJones68), Shaka Senghor (@ShakaSeghnor), and Chris Lyons (@clyons) True redemption can be hard to come by in our justice system today. And yet, we need it more than ever before. In this episode (based on an event hosted by Andreessen Horowitz's Cultural Leadership Fund), CNN news commentator and author Van Jones and Shaka Senghor, author of the New York Times bestseller Writing my Wrongs and director's fellow of the MIT Media Lab, discuss the U.S. prison system; the human potential for redemption; and how we begin to go about normalizing restorative justice in our society. The conversation, introduced by a16z partner Chris Lyons, followed screening of an episode of Van Jones' new series, The Redemption Project. The eight-part series looks at the families of victims of a life-altering crime as they come together to meet their offender; this episode featured the meeting between a police officer along with the man who shot him as a young boy of 17 years, decades earlier. The episode also includes two spoken word performances before and after the conversation, from two formerly incarcerated artists: first, Kevin Gentry, with "My Heart"; and second, Missy Hart, with "Bloom: A Trilogy." Both are contributors to The Beat Within, a publication and organization that serves youth across California country juvenile halls and encourages literacy, self-expression, and community.
May 30, 2019
with Andrew Lo (@AndrewWLo) and Jorge Conde (@JorgeCondeBio) The advent of new gene and cell therapies are beginning to approach that holy grail of medicine—that of a possible cure. But they are also more expensive than any medicines ever sold before. In this episode, MIT economist Andrew Lo and a16z General Partner on the Bio Fund Jorge Conde discuss how exactly we place an economic value on a cure; the questions we still need to figure out, like who should pay for what and how; and how we need to start thinking about handling the coming influx of highly priced medicines like these into our healthcare system. If we think about these payments as a kind of 'mortgage for a cure,' what happens when your gene therapy mortgage defaults? How would payment plans like these move between insurance plans? Lo and Conde also discuss the broader context in our healthcare system, the economics and risk of drug discovery and development overall – and finally, how our markets might just function more like biological systems than anything else.
May 27, 2019
with Laurene Powell Jobs (@LaurenePowell) and Ben Horowitz (@bhorowitz) Laurene Powell Jobs is, among many other things, founder and President of the Emerson Collective -- the social impact firm she founded to drive change and reform through philanthropy, investing, and policy solutions. In this episode of the a16z Podcast, Ben Horowitz interviews Powell Jobs on everything from what made her who she was, growing up in the working class rural hills of New Jersey, to how the Emerson Collective does what it does (and why it's a collective, for that matter). What motivates the investments the Emerson Collective makes—and what do they all share in common, across such a broad range of areas, from education to immigration to media? This conversation originally took place at our annual innovation a16z Summit in November 2018 — which features a16z speakers and invited experts from various organizations discussing innovation at companies small and large.
May 20, 2019
with David Ulevitch (@davidu) and Sonal Chokshi (@smc90) Since the startup (and founder) journey doesn't go neatly linear from technical to product to sales, tightening one knob (whether engineering or marketing or pricing & packaging) creates slack in one of the other knobs, which demands turning to yet another knob. So how do you know what knob to focus on and when? How do you build the right team for the right play and at the right time? It all depends on "What time is it": where are you on the journey, and where do you want to go... In this episode of the a16z Podcast, general partner David Ulevitch (in conversation with Sonal Chokshi) shares hard-earned lessons on these top-of-mind questions for founders; as well as advice on other tricky topics, such as pricing and packaging, balancing between product visionary vs. product manager, how to manage your own time (and psychology!) as your company grows, and more. Much of this is based on his own up-and-down, inside-outside, big-small-big-small, long journey as CEO (and CTO) for the company he co-founded, OpenDNS. The company was later acquired by Cisco after it pivoted from consumer to enterprise. Speaking of, what are the latest shifts and nuances in selling and buying enterprise products, beyond the phrase "consumerization of enterprise"? Or beyond the cliché of "design thinking" -- how does one go beyond user experience and beyond things like fun gifs (which are pronounced, ahem, "jifs") to focusing on the whole customer experience, and earning the right to be complicated? All this and more in this episode... plus the magic 5 words that will help any CEO (and anyone, really). --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
May 16, 2019
Do you sometimes wish you had been born in a different decade so you could have worked on the fundamental building blocks of modern computing? How fun, challenging, and fulfilling would it have been to work on semiconductors in the 1950s or Unix in the 1960s (both at Bell Labs) or personal computers at the Homebrew Computer Club in the 1970s or on the Internet browser at the University of Illinois at Urbana-Champaign (and later Mountain View, CA) in the 1990s? Good news: it’s not too late. There’s a new computing platform being built today by a vibrant and rapidly growing cryptocurrency community. You might have noticed some of your coworkers and friends leaving big stable tech companies to join crypto startups. In this episode, which originally appeared on YouTube, a16z crypto partner Ali Yahya (@ali01) talks with Frank Chen (@withfries2) about five challenging problems the community is trying to solve right now to enable a new computing platform and a new set of killer apps: *Scaling decentralized computing *Scaling decentralized storage *Scaling decentralized networks *Establishing trusted identities and reputation *Establishing trusted governance models If you’re a software engineer, product manager, UX designer, investor, or tech enthusiast who thrives on the particular challenges of building a new computing platform, this is the perfect time to join the crypto community. ***** The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
May 12, 2019
with Emily Oster (@ProfEmilyOster) and Hanne Tidnam (@omnivorousread) Are chia seeds actually that good for you? Will Vitamin E keep you healthy? Will breastfeeding babies make them smarter? There’s maybe no other arena where understanding what the evidence truly tells us is harder than in health… and parenting. And yet we make decisions based on what we hear about in studies like the ones listed above every day. In this episode, Brown University economics professor Emily Oster, author of Expecting Better and the recently released book Cribsheet: A Data-driven Guide to Better, More Relaxed Parenting, from Birth to Preschool, in conversation with Hanne Tidnam, dives into what lies beneath those studies... and how to make smarter decisions based on them (or not). Oster walks us through the science and the data behind the studies we hear about -- especially those hot-button parenting issues that are murkiest of all, from screen time to sleep training. How we can tell what’s real and what’s not? Oster shows us the research about how these guidelines and advice that we are "supposed" to follow get formalized and accepted inside and outside of healthcare settings -- from obstetrics practices to pediatrics to diet and lifestyle; how they can (or can’t) be changed; and finally, how the course of science itself can be influenced by how these studies are done.
May 8, 2019
with @annieduke, @pmarca, and @smc90 Every organization, whether small or big, early or late stage -- and every individual, whether for themselves or others -- makes countless decisions every day, under conditions of uncertainty. The question is, are we allowing that uncertainty to bubble to the surface, and if so, how much and when? Where does consensus, transparency, forecasting, backcasting, pre-mortems, and heck, even regret, usefully come in?Going beyond the typical discussion of focusing on process vs. outcomes and probabilistic thinking, this episode of the a16z Podcast features Thinking in Bets author Annie Duke -- one of the top poker players in the world (and World Series of Poker champ), former psychology PhD, and founder of national decision education movement How I Decide -- in conversation with Marc Andreessen and Sonal Chokshi. The episode covers everything from the role of narrative -- hagiography or takedown? -- to fighting (or embracing) evolution. How do we go from the bottom of the summit to the top of the summit to the entire landscape... and up, down, and opposite?The first step to understanding what really slows innovation down is understanding good decision-making -- because we have conflicting interests, and are sometimes even competing against future versions of ourselves (or of our organizations). And there's a set of possible futures that result from not making a decision as well. So why feel both pessimistic AND optimistic about all this??
May 8, 2019
In a followup to one of our most popular podcast episodes which originally aired in April 2017 (https://a16z.com/2017/04/03/cryptocurrencies-protocols-appcoins/), a16z Crypto Fund General Partner Chris Dixon returns to talk with Olaf Carlson-Wee of Polychain Capital in a free-wheeling conversation about the seven major trends they see happening in blockchain computing now as we shift from basic protocol design to pragmatic product launches: - Improving developer productivity - Scaling out versus scaling up - On-chain governance - Proof of Stake Networks, and especially their resilience to attacks - 2017: year of of fund raising, 2019: year of launches - Autonomous and re-mixable code - Killer apps: distributed finance and beyond This conversation was originally recorded for our YouTube channel: https://www.youtube.com/c/a16zvideos The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investor or prospective investor, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund which should be read in their entirety.)Past performance is not indicative of future results. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Please see a16z.com/disclosures for additional important information.
May 1, 2019
As companies digitize, they change the way they make decisions: decisions are made lower in the organization, based on data, and increasingly automated. This creates opportunities for startups creating new ways to collect and analyze data to support this new style of decision making. In this episode (which originally aired as a YouTube video), Jad Naous (@jadtnaous) ‏and Frank Chen (@withfries2) discuss this change and the startup opportunities these changes create. The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investor or prospective investor, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund which should be read in their entirety.)Past performance is not indicative of future results. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Please see a16z.com/disclosures for additional important information.
April 26, 2019
with Jorge Conde (@JorgeCondeBio), Julie Yoo (@julesyoo), and Hanne Tidnam (@omnivorousread) Building a software company in healthcare is hard -- and comes along with unique challenges no other entrepreneurs face. In this conversation, a16z bio general partner -- and previous founder of genomics company Knome -- Jorge Conde; and a16z bio partner and former founder Julie Yoo (of patient provider matching system, Kyruus) share their mistakes and hard earned lessons learned with a16z partner Hanne Tidnam. Why is this so damn hard? How should founders think about this space differently? What are the specific things that healthcare founders can do -- when, where, and why? You'll wish you only knew this when you started your own company!
April 20, 2019
Join longtime Apple software engineer Ken Kocienda in conversation with a16z Deal and Research operating partner Frank Chen for an insider’s account of how Apple designed software in the golden age of Steve Jobs, spanning products like the first release of Safari on MacOS to the first few releases of the iPhone and iOS (very first codename: "Purple"). Ken vividly shares about the creative process, how teams were organized, what it was like demo'ing to Steve Jobs, and many other fun stories. This episode originally aired as a YouTube video, and throughout, we repeatedly probe the question: is Apple's obsession with secrecy during the product development process a feature or a bug?
April 7, 2019
In this episode of the a16z Podcast -- which originally aired as a video on YouTube -- general partner Alex Rampell (and former fintech entrepreneur as the CEO and co-founder of TrialPay) talks with operating partner Frank Chen about the quickly changing fintech landscape and, even more importantly, why the landscape is changing now. Should the incumbents be nervous? About what, exactly? And most importantly, what should big companies do about all of this change? But the conversation from both sides of the table begins from the perspective of the hungry and fast fintech startup sharing lessons learned, and then moves to more concrete advice for the execs in the hot seat at established companies. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investor or prospective investor, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund which should be read in their entirety.) Past performance is not indicative of future results. Any charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Please see https://a16z.com/disclosures for additional important information.
April 3, 2019
with Nick Quah (@nwquah), Connie Chan (@conniechan), and Sonal Chokshi (@smc90) It's a podcast about podcasting! About the state of the industry, that is. Because a lot has changed since we recorded "a podcast about podcasts" about four years ago: podcasts, and interest in podcasting -- listening, making, building -- is growing. But by how much, exactly? (since various stats are constantly floating around and often out of context); and what do we even know (given that no one really knows what a download is)?And in fact, how do we define "podcasts": Should the definition include audio books... why not music, too, then? So much of the podcasting ecosystem -- from editing tools to the notion of a "CD phase" to music companies like Spotify doing more audio deals -- stems from the legacy of the music industry. But other analogies -- like that of the web and of blogging! -- may be more useful for understanding the podcasting ecosystem, too. Heck, we even throw in an analogy of container ships (yes, the ocean kind!) to help out there.If we really think medium-native -- and borrow from other mediums and entertainment models, like TV and streaming and even terrestrial radio -- what may or may not apply to podcasting as experiments evolve? In this hallway-style jam of an episode, Nick Quah (writer and publisher of Hot Pod) joins a16z general partner Connie Chan (who covers consumer startups among other things) in conversation with Sonal Chokshi (who is also showrunner of the a16z Podcast) to talk about all this and more. We also discuss the obvious and the not-so-obvious aspects of monetization, discovery, search, platforms... and where are we in the cycles of industry fragmentation vs. consolidation, bundling vs. unbundling, more? And where might opportunities for entrepreneurs, toolmakers, and creators lie? --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investor or prospective investor, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund which should be read in their entirety.)Past performance is not indicative of future results. Any charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Please see https://a16z.com/disclosures for additional important information.
March 30, 2019
with Benedict Evans (@benedictevans) and Steven Sinofsky (@stevesi) What does Apple's recent event — in which a range of new services was announced, from Apple News Plus to Apple TV Plus to the Apple card — mean for the company's overall strategy and tactics? In this another of a16z's 'hallway conversations', Benedict Evens and Steven Sinofsky discuss the build up, announcements, and postmortem of the recent Apple event, and consider what it all means in terms of a big company's evolution into services. How many different places is Apple now putting a tap into the tree, with new subscriptions available? What’s the positioning underlying all those different services, from a new credit card to new magazines and content, all bundled up together? The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates.This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investor or prospective investor, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund which should be read in their entirety.)Past performance is not indicative of future results. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Please see https://a16z.com/disclosures for additional important information.
March 25, 2019
with Safi Bahcall (@safibahcall), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90) A "moonshot" is a destination (like going to the moon, quite literally) -- but nurturing "loonshots" (which often involves a number of stumbles along the way) is how we get there. This goes beyond the trite mantra of failing fast! It is about not having "false fails" or not killing the seemingly small ideas that could lead to outsized yet unexpected outcomes, observes Safi Bahcall (physicist, ex-startup founder, and CEO of a public biotech company), author of the new book, Loonshots: How to Nurture the Crazy Ideas That Win Wars, Cure Diseases, and Transform Industries.So in this episode of the a16z Podcast -- in conversation with a16z bio general partner Vijay Pande and Sonal Chokshi -- Bahcall shares why concepts like "disruptive innovation" cause him gas; why doing market projections can sometimes be crap; and why most management books that focus on culture are b.s.Because CEOs and culture, argues Bahcall, do not control organizational behavior... but hidden incentives, "phase transitions", and specific control parameters do. So how can organizations -- of any size, big or small -- be in two states at the same time: both fluid and stable, soft and solid, with high entropy yet bound energy, and both artists and soldiers? The answer may be in a more scientific, less "squishy" framework for management at the intersection of physics and economics. Big empires always miss the small but important new ideas... can this be why?
March 16, 2019
with Brian Koppelman (@briankoppelman), Marc Andreessen (@pmarca), and Sonal Chokshi (@smc90) The writer-showrunner is a relatively new phenomenon in TV, as opposed to film, which is still a director-driven enterprise. But what does it mean, as both a creative and a leader, to “showrun” something, whether a TV show… or a startup? Turns out, there are a lot of parallels with the rise of the showrunner and the rise of founder-CEOs, all working (or partnering) within legacy systems. But in the day to day details, really “owning” and showunning something — while also having others participate in it and help bring it to life — involves doing the work, both inside and out. This special, almost-crossover episode of the a16z Podcast features Billions co-showrunner Brian Koppelman — who also co-wrote movies such as Rounders and Ocean’s 13 with his longtime creative partner David Levien — in conversation with Marc Andreessen (and Sonal Chokshi). The discussion covers everything from managing up — when it comes to executives or investors sharing their “notes” aka “feedback” on your work — to managing down, with one’s team; to managing one’s partners (or co-founders)… and especially managing yourself. How to tame those irrational emotions, that ego? Ultimately, though, it’s all about unlocking creativity, whether in writing, coding, or other art forms. Because something surprising happened: Instead of TV going the way of music à la Napster with the advent of the internet, we’re seeing the exact opposite — a new era of “visual literature”, a “Golden Age” of television and art. Are artists apprenticing from other artists virtually, learning and figuring out the craft (with some help from the internet, mobile, TV)? And if we really are seeing “the creative explosion of all time”, what does it take to explode our own creativity in our work, to better run the shows of our lives? All this and more in this episode of the a16z Podcast… as well as some Billions behind-the-scenes (and light spoilers, alerted within!) towards the end.
March 14, 2019
When people talk about trends in education technology, they often focus on how to disrupt higher education in the U.S., whether it's about breaking free of the "signaling" factor of elite educations or how to shift education out of its "cottage industry" mindset to achieve greater scale. However, in China, the transformation of education is already well underway, with a fast-growing ecosystem built around lifelong learning. In fact, one of the largest demographic groups paying for education in China is actually not college students -- it's college graduates, aged 26 through 35.In this episode -- which originally aired as a video on our YouTube channel -- a16z general partner Connie Chan talks with operating partner Frank Chen about the lifelong learning ecosystem in China; what it means for startups there; and lessons for entrepreneurs everywhere... or will these techniques even work outside of China?
February 26, 2019
with George Church (@geochurch) and Jorge Conde (@JorgeCondeBio) Renowned scientist George Church is known for his groundbreaking work and methods used for the first genome sequence, and for his work in genome editing, writing & recoding -- in fact, Church’s innovations have become an essential building block for most of the DNA sequencing methods and companies we see today. In this conversation, a16z bio general partner Jorge Conde -- who also founded a company with Church out of the George Church Lab -- take us on a wild journey into the scientist’s mind and work, starting with what the leading pioneer in the space makes of where we are today with CRISPR (especially given recent news about CRISPR babies in China), to the broader implications of all of this on a cultural level, and finally to what it really takes to go from science fiction, to lab, to reality.
February 24, 2019
with Peter Ludwig, Qasar Younis (@qasar), and Sonal Chokshi (@smc90) When people talk about autonomous vehicles, we hear everything from "we're much closer than you think" to "we're much further than you think". So where are we, really, in the widespread reality of autonomous vehicles today? It depends, of course, on how you define autonomy -- which is where a handy recap and update of the SAE (Society of Automotive Engineers) levels of autonomy comes in. But still, given everything out there from self-driving shuttles to Teslas, it's really hard to tell just where we are and where the nuances of, say, Level 2-plus vs. Level 3 might come in. This episode of the a16z Podcast takes a quick pulse on where we are in the state of autonomy in 2019 when it comes to autonomous cars, shuttles, robots -- basically any "autonomous" and/or "self-driving" vehicle out there -- as well as the analogy of mobile for understanding the space: where it works, where it breaks down. But did even the mobile industry itself really have a clear iPhone "moment"? When did mobile devices that seemed so limited -- or seemed like just "toys" -- suddenly (or not so suddenly) go to an apps layer that we use every single day? How do we build "the rails" and "the trains" at the same time in this case? And perhaps most importantly, where will the spoils of this new wave of innovation go -- to Silicon Valley or Detroit? Or outside the U.S.? Who are the players? How do regulatory -- and quite frankly, nationalistic -- concerns come into play here? And finally, how does one balance the desire to embrace innovation in an open and fast, yet still very thoughtful and safe way? The answers, according to Applied Intuition co-founder and CEO Qasar Younis and CTO Peter Ludwig (in conversation with Sonal Chokshi), have to do with commodities and capitalism, with science and science fiction, with simulation and software as infrastructure, and more... And really, how we define autonomy now, and in the future.
February 17, 2019
Bobby Kotick is the CEO of Activision Blizzard (a merger he engineered); it's one of only two video gaming companies in the Fortune 500, and the largest game network in the world. The company is responsible for some of the most iconic entertainment franchises, including Call of Duty, Candy Crush, Overwatch, and World of Warcraft -- as well as its own professional esports league. So in this episode of the a16z Podcast, Marc Andreessen interviews Kotick on everything from the evolution of video games in the 1980s to gaming trends more broadly. What changes as gaming goes from "just for nerds" to "just for kids" and spreads more broadly into entertainment and cultural phenomena (esports, Fortnite, Pokemon Go, etc.)... both online and offline? The conversation originally took place at our annual innovation a16z Summit in November 2018 -- which features a16z speakers and invited experts from various organizations discussing innovation at companies small and large. You can also see other podcasts and videos from this event here: https://a16z.com/tag/summit-2018/
February 16, 2019
with Ryan Caldbeck (@ryan_caldbeck), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90) It's clear that all kinds of commerce companies and consumer products have been disrupted -- or enabled -- by tech. Yet for certain categories, like consumer packaged goods (CPG), it seems like tech hasn't changed things very much. How is the rise of so-called "micro-brands" (or emerging brands) playing out here? And, how is it possible that "real" -- different -- innovation isn't really happening in the CPG industry, despite the tremendous legacy of brand, talent, and more in the space? How are CPG companies tackling grocery, which represents the perfect end-capsule and case study of challenges -- and opportunities -- in going from offline to online, from online to offline, and more? As for grocery itself, stores themselves (in the U.S. at least) haven't changed very much due to tech, either... is it a last-mile delivery thing; could we also possibly move to distribution-only centers in the future? Finally, while the holy grail of performance marketing and personalization remains elusive for the industry -- let’s face it, most brands are still guessing in the dark (and forget trying to customize offerings!) -- even going direct-to-consumer (DTC) hasn't been shining as much of a light here as one might expect. Or so argue the guests in this episode of the a16z Podcast, featuring Ryan Caldbeck of CircleUp, along with a16z general general partner Jeff Jordan, in conversation with Sonal Chokshi. Cuz this episode is all about CPG, DTC; micro-brands, yah you know, all kinds of commerce.
February 14, 2019
with Kate Darling (@grok_) and Hanne Tidnam (@omnivorousread) We already know that we have an innate tendency to anthropomorphize robots. But beyond just projecting human qualities onto them, as we begin to share more and more spaces, social and private, what kind of relationships will we develop with them? And how will those relationships in turn change us? In this Valentine’s Day special, Kate Darling, Researcher at MIT Labs, talks with a16z's Hanne Tidnam all about our emotional relations with robots. From our lighter sides -- affection, love, empathy, and support -- to our darker sides, what will these new kinds of relationships enhance or de-sensitize in us? Why does it matter that we develop these often intense attachments to these machines that range from tool to companion -- and what do these relationships teach us about ourselves, our tendencies and our behaviors? What kinds of models from the past can we look towards to help us navigate the ethics and accountability that come along with these increasingly sophisticated relationships with robots?
February 12, 2019
with Chris Burniske (@cburniske), Joel Monegro (@jmonegro), Denis Nazarov (@Iiterature), and Jesse Walden (@jessewldn) When designing cryptonetworks -- really, emerging economies -- how do we avoid some of the monetary and fiscal policy failings of "real-world" economies? Like not separating currency and capital, which accelerated and spread economic growth through the former... but also concentrated the latter into the hands of a few? Yet how can we empower users to access capital while also managing risk? If the promise of cryptonetworks is to better align incentives and value capture, then we can't make the same mistakes as we did in traditional economies. We also have the chance to do novel things not possible in the physical world, through software. So this episode of the a16z Podcast -- featuring voices from Placeholder VC and a16z Crypto -- goes deep into the nuances and mechanisms of cryptonetworks, tokens, and decentralized applications at every layer of the "stack". Chris Burniske (who has written a lot about financial modeling-influenced frameworks for analyzing crypto) and Joel Monegro (who has written about "fat protocols", and once managed the Digital Economy Department at the Ministry of Industry and Commerce of the Dominican Republic) of Placeholder VC discuss and debate all of the above -- and more! -- with a16z crypto's Denis Nazarov and Jesse Walden (co-founders of Mediachain, which was acquired by Spotify). Throughout the history of information technology, we've gone from hardware to software, and software to data. So what's next, what's the layer above data? The answer is governance -- which gives more people a way to participate in decision making around a given network -- but the answer for how to implement the best governance isn't so clear.
February 10, 2019
with Phil Daian (@phildaian) and Ali Yahya (@ali01) Whether in corporations, boardrooms, or political elections, voting is something we see in all kinds of social systems... including blockchains. It's the natural human tendency for how to organize decisions, and in distributed systems without centralized middlemen, it's the only clear Schelling point we can come up with. But too many people design voting mechanisms in distributed systems in isolation -- sometimes naively "porting over" assumptions from the real world or from simple cryptoeconomic models without thinking through the economic adversaries present in a larger, more rational (vs. "honest") game-theoretic system. So how are blockchain systems different from real-world paper and electronic voting systems? How can such systems be gamed, and what are the implications for cryptoeconomic security... as well as the governance of distributed organizations? This hallway-style episode of the a16z Podcast covers all this and more. Recorded as part of our NYC roadtrip, it features Cornell Tech PhD student and software engineer Phil Daian, who researches applied cryptography and smart contracts -- and who also wrote about "On-chain Vote Buying and the Rise of Dark DAOs" in 2018 (with Tyler Kell, Ian Miers, and his advisor Ari Juels). Daian is joined by a16z crypto partner Ali Yahya (previously a software engineer and machine learning researcher at GoogleX and Google Brain), who also recently presented on crypto as the evolution -- and future -- of trust. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
February 3, 2019
with Jyoti Bansal (@jyotibansalsf), Peter Levine, Satish Talluri (@satishtalluri), and Sonal Chokshi (@smc90) One of the toughest challenges for founders -- and especially technical founders who are used to focusing so much on product features over sales -- is striking "product-market fit". The concept can be defined many ways, but the simple definition shared in this episode is: it's when you understand the business value of your product. And that comes down to users, which is where the concept of "product-market-sales fit" comes in, observes Jyoti Bansal, founding CEO of AppDynamics (which was acquired by Cisco for $3.7B the night before it was to IPO). Bansal shares this and other key milestones and frameworks for company building in conversation with a16z general partner Peter Levine; enterprise deal team partner Satish Talluri (who was a director of product and growth operations there); and Sonal Chokshi. So in that shift from product-market fit to product-market-SALES fit, how much should you optimize your go-to-market for product... and even the other way around? What does this mean for product design and product management? When should companies offer services? As for pricing, how do you know you're not leaving value on the table? Again, it comes down to product-market fit: If your business case is strong, you will not be leaving money on the table, argues Bansal in this special podcast series on founder stories and lessons learned in enterprise go-to-market.
January 31, 2019
with Mark Leslie (@mleslie45) and Peter Levine What does it actually take to win at enterprise sales? In this episode, Mark Leslie, former CEO and chairman and founding team member of Veritas Software, and a lecturer at the Stanford Graduate School of Business, and a16z general partner Peter Levine -- who worked together at Veritas -- share stories from the field all about sales and entrepreneurship in the enterprise. The wide-ranging conversation covers everything from what makes a good salesperson; to how to actually close that deal; to how to build a company that best incentivizes your sales reps. This episode is based on a conversation that originally took place at an event held at Andreessen Horowitz for veterans participating in the BreakLine education and hiring program for shifting veterans into careers in the tech industry.
January 30, 2019
with Peter Levine, Bob Tinker, and Hanne Tidnam (@omnivorousread) For consumer companies, often when the holy grail of product-market fit is achieved, the company takes off: magic happens, growth unlocks. Enterprise B2B companies face a different challenge. Sometimes, despite achieving product-market fit (and knowing when you've achieved it) and winning your first cohorts of renewing customers -- growth remains a challenge. Industry analyst maps are riddled with the logos of enterprise B2B companies who built outstanding products, won outstanding initial sets of customers... and then ultimately failed to scale. In this episode of the a16z Podcast, Bob Tinker, author of the book Survival to Thrival and founding CEO of MobileIron, and a16z general partner Peter Levine, talk with Hanne Tidnam all about how to find the right go-to-market fit for the enterprise startup. How do founders avoid that moment of reckoning after product-market fit, but before growth? When should an enterprise startup accelerate sales investments?  -- the "Goldilocks problem" (not too early, not too late!) -- and pick the right sales team and go-to-market model for their product and their customers? And if you're stuck in that moment where growth stalls, what are the right tools to get out of it? What are the important metrics to know both where you are, and when you're out of the woods?
January 26, 2019
Veterinary oncology can inform human oncology, and vice versa -- providing a better model for looking at drug performance, interrelationships, and more. Especially when you add in data (there's no "doggy HIPAA!") and networks to get a "living laboratory at scale". Or so argues Amy Abernethy (Chief Medical and Chief Scientific Officer at Flatiron Health and advisor to One Health), who was recently named the new Principal Deputy Commissioner of the FDA, pending ethics clearance; and Christina Lopes, CEO and co-founder of One Health; in conversation with a16z bio general partner Jorge Conde. Dogs -- as a species, as pets, as companions, as family members -- evolved alongside humans, so are actually more similar to us... not just genetically and in terms of the biologic pathways that may cause cancer, but also in exposure to similar environmental factors as well. But what does this all mean when it comes to thinking about real-world evidence in science, human clinical trials, and more broadly, building a bio company? How can product designers -- of all kinds -- backwards-architect their product roadmap for data network effects? And how can bio founders keep both a big-picture roadmap in mind while also focusing on specific milestones, and while working across unconnected disciplines as well? We cover all this and more in this special episode of the a16z Podcast, recorded during the recent J.P.M. healthcare conference in San Francisco. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
January 17, 2019
with Joel de la Garza, Jonathan Lusthaus, and Hanne Tidnam (@omnivorousread) The idea of the cybercriminal as lone wolf or hobby hacker is no longer much of a reality. Instead, the business of cybercrime looks a lot more just like that -- a large, global technology business, with many of the associated structures, challenges, and even casts of characters that legitimate businesses have. In this conversation, a16z's Joel de la Garza, a16z operating partner for information security (formerly CSO of Box and head Citigroup's Cyber Intelligence Center), and Hanne Tidnam, discuss with Jonathan Lusthaus -- Director of the Human Cybercriminal Project at the University of Oxford -- the evolution of the industry of cybercrime from single perpetrator into a sprawling and sophisticated international industry as discussed in his new book, Industry of Anonymity: Inside the Business of Cybercrime. A dive into the sociological, operational, and tactical realities of this murky underworld, Lusthaus and de la Garza discuss what the current industry has evolved into -- who the players are, what they are motivated by, and specialize in -- as well as how basic ideas like trust and anonymity function in a world where no one wants to get caught. How do criminal nicknames function as brand? Which countries tend to specialize in what kinds of crime, and why? And most of all, what changes when you begin to think of the business of cybercrime as an industry?
January 17, 2019
with Benedict Evans (@benedictevans) and Steven Sinofsky (@stevesi) Every year, the Consumer Electronics Show (CES) puts the latest and greatest developments in consumer technology on display in Vegas. But beyond the excitement and the hype, what's really here -- or not here -- to stay? Will televisions roll up into tiny boxes? Will Alexa find her way into electric carving knives? Which of these new gadgets will stand the test of time?  In this episode of the a16z podcast, Benedict Evans and Steven Sinofsky share their take not only on what this year’s show had to offer, but the broader trends at play. From the evolution of the smart home and voice interfaces to the cycle of bundling and unbundling and the future of TV and entertainment, the discussion is a pulse check on where we're at. --- The content provided here is for informational purposes only, and does not constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16z.com should be relied on in any manner as advice. Please see https://a16z.com/disclosures/ for further information. This podcast may contain forward-looking statements relating to the objectives, opportunities, and the future performance of the U.S. market generally as well as specific publicly traded companies. Forward-looking statements may be identified by the use of such words as; “believe,” “expect,” “anticipate,” “should,” “planned,” “estimated,” “potential” and other similar terms. Examples of forward-looking statements include, but are not limited to, estimates with respect to financial condition, results of operations, and success or lack of success of any particular investment strategy. All are subject to various factors, including, but not limited to general and local economic conditions, changing levels of competition within certain industries and markets, changes in interest rates, changes in legislation or regulation, and other economic, competitive, governmental, regulatory and technological factors affecting a portfolio’s operations that could cause actual results to differ materially from projected results. Such statements are forward-looking in nature and involve a number of known and unknown risks, uncertainties and other factors, and accordingly, actual results may differ materially from those reflected or contemplated in such forward-looking statements. Prospective investors are cautioned not to place undue reliance on any forward-looking statements or examples. None of AH Capital Management, L.L.C. or any of its affiliates, principals, employees nor any other individual or entity assumes any obligation to update any forward-looking statements as a result of new information, subsequent events or any other circumstances. All statements made herein speak only as of the date that they were made.
January 16, 2019
with Susannah Fox (@susannahfox), Anil Sethi (@anilsethiusa / @ciitizencorp), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90) The problem of "dark data" in healthcare isn't just a feel-good empowerment thing, but a structural issue that leads to miscommunication and extra friction, different players in the entire healthcare system not being able to collaborate with each other, and just major missed opportunities all round. And yes, it also leads to lack of empowerment for patients, not to mention doctors too (who often have less than 30 minutes on site to do their jobs). But we already know all that. What's not clear is WHY and HOW is this the case, when the very point of HIPAA -- the Health Insurance Portability and Accountability Act (of 1996!) -- is to make data portable, not private. That is, IF patients know to ask for it... and can easily get it. So what if we could have a sort of permissioned "permissionless innovation" for healthcare data, not only bringing all that dark data to light, but more importantly -- borrowing from the history of internet innovation -- letting all sorts of expected and unexpected uses be built on top as a result? What happens when data and entities can talk to each other (à la APIs) through patients at the center of the circle of data? From the Dr. Google problem (or opportunity!) to clinical trials and even the opioid crisis, we -- Susannah Fox (former CTO of the U.S. Department of Health and Human Services); Anil Sethi (CEO and founder of Ciitizen); and a16z bio general partner Vijay Pande; in conversation with Sonal Chokshi -- explore all this and more in this episode of the a16z Podcast. Let there be light!
January 14, 2019
with Vas Narasimhan (@vasnarasimhan), Jorge Conde (@jorgecondebio), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90) On average, only 1 out of 20 medicines works when we actually bring them into the human body, and these rates of success haven't moved much in the pharma industry overall in the past 15 years, despite much scientific progress. Because if you really think about it, it's incredible that we find any human medicine that works at all, given that human beings are the product of billions of years of evolution, and represent an incredibly complex system we do not fully understand. Yet the business of the pharma industry -- and Novartis in particular, which covers everything from generics to innovative medicines -- is not that different from other large enterprises when it comes to managing R&D and pipelines of ideas, talent, and sales. So in this conversation, a16z bio general partners Jorge Conde and Vijay Pande with Sonal Chokshi interview Vas Narasimhan, CEO of Novartis. How does the world's largest producer of medicines in terms of volume -- 70. billion. doses. a. year. -- balance the science and the business of innovation? How does an enterprise at such vast scale make decisions about what to build vs. buy, especially given the fast pace of science today? How does it balance attitudes between "not invented here" and "not invented yet"? Narasimhan also takes us through the latest trends in therapeutics, such as cell and gene therapies (like CAR-T for cancer and more); RNA-based modalities; and others -- a sweeping tour from small molecules to large molecules to proteins and other modalities for making medicines. But where does tech come into all this, and where are we, really, on science becoming engineering? Why do both big companies and bio startups now need to get market value signals (not just approvals!) from payers earlier in the process of making therapeutics? And beyond all that, how could clinical trials be reinvented? Finally, what should all scientific (and all technical) leaders know when it comes to leadership? All this and more in this episode of the a16z Podcast, recorded recently on the road while at the J.P.M. health conference in San Francisco.
January 11, 2019
with James J. Collins, Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread) The idea of 'designing biology' -- once science fiction -- has over the last 20 years become just... science. In this episode, a16z bio general partner Vijay Pande with Hanne Tidnam talk all about the field of synthetic biology with James J. Collins, professor of bioengineering at MIT. Collins, whose work in synthetic biology and systems biology pioneered the field, has also launched a number of companies and received numerous awards and honors (including a MacArthur "Genius" Award, an NIH Director's Pioneer Award, and Sanofi-Institut Pasteur Award). This wide-ranging conversation about the birth of synthetic biology covers everything from the founding story of the discipline to what "engineering and designing" biology really looks like in action -- when instead of engineering electrons, you are engineering toggle switches for genes -- to the disciplinary differences (and synergies) between how biologists and engineers see the world. What are the engineering and design principles, techniques, approaches that work best when applied to science? How does building a company in this new space look different, in terms of platforms and products? And how is this new field changing education in science, all the way down to kits that allow you to play with the machinery of a cell... at home... and even in middle school?
January 9, 2019
The past and future of marketplace startups -- where are we? Ever since eBay popularized an internet meeting place for buyers and sellers of, well, just about everything, we’ve been waiting for 100 other at-scale marketplaces for everything else, including services. So in this hallway-style episode of the a16z Podcast (originally recorded as a video) Li Jin -- co-author with Andrew Chen of this post -- chats with a16z Deal & Research team operating partner about why there aren’t 100 thriving marketplaces for services yet... And what’s changing to make this next wave of marketplace startups super exciting. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
December 29, 2018
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen) This episode of the a16z Podcast features the rare combination of a16z co-founders Marc Andreessen and Ben Horowitz in conversation, together, with economist Tyler Cowen (chair of economics at George Mason University and chairman and general director of the Mercatus Center there, and host of his own podcast.) The conversation originally took place at our most recent annual innovation Summit -- which features a16z speakers and invited experts from various organizations discussing innovation at companies large and small, as well as tech trends spanning bio, consumer, crypto, fintech, and more. This discussion covers Ben and Marc's marriage, er, partnership; the evolution of VC and "talent as a network"; and where are we right now on industries being affected by tech (such as retail) and tech trends (such as VR/AR and wearables) -- and where are we going next? Finally, is software eating culture... or is it the other way around?
December 25, 2018
In his book (and podcast), Brian McCullough chronicles the history and evolution of the internet -- from college kids in a basement and the dot-com boom, to the applications built on top of it and the entrepreneurs behind them. General partner Chris Dixon chats with McCullough about How the Internet Happened -- and more broadly, about how tech adoption and innovation happens. --- The content provided here is for informational purposes only, and does not constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. Please see https://a16zcrypto.com/disclosures/ for further information.
December 23, 2018
with Bernard J. Tyson (@bernardjtyson) and Ben Horowitz (@bhorowitz) Bernard J. Tyson is the chairman and CEO of Kaiser Permanente, a $73 billion non-profit health organization that provides healthcare and coverage with more than 22,000 physicians caring for more than 12.2 million members across 9 states. In  this conversion with a16z co-founder and general partner Ben Horowitz -- which originally took place at a16z's annual innovation summit, which focuses on building the future and included an entire theme focused on bio and healthcare -- Tyson shares his thoughts on the state of healthcare today and where it might be going. How does an end-to-end healthcare system (like Kaiser's) work in terms of assuming risk and responsibilities, while also maximizing value and lifetime care over a “head in the bed”? What's the impact of -- and challenges in adopting -- technology in healthcare today? And finally, how does one strike a balance between affordability, quality, and lifetime care... and between innovating and addressing immediate needs? All this and more in this episode. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
December 21, 2018
with Andy Milenius (@realzandy), Jesse Walden (@jessewldn), and Sonal Chokshi (@smc90) The history, evolution, and use of money revolves around the important concept of debt: It’s what allows us to “time travel” and build toward the future — growing livelihoods, businesses, and the overall economy as a result. When it comes to crypto, however, this concept plays a key role as a way to potentially stabilize the volatility of cryptocurrencies, and more importantly, provide a more stable medium of exchange so key applications can be built on top of blockchains. That’s where stablecoins (cryptocurrencies pegged to a more stable asset, such as fiat dollars) come in. Because they’re deployed on top of blockchains, they retain the advantages of cryptocurrencies — digital, global, easily transferable, decentralized. And because open source networks are more transparent and auditable, these systems are far less opaque than, say, the huge house of cards that collapsed in the case of the 2008 financial crisis. But beyond bringing more people into a better financial system, why do stablecoins like Dai — and Maker, one of the oldest decentralized autonomous organizations (DAOs) on the Ethereum blockchain — matter to the crypto developer community? To banks? To anyone who thinks about the future of innovation… or even the future of the firm, and the future of work? How do (and don’t) DAOs and these kinds of smart contracts change everything we know about management and software development? This episode of the a16z Podcast explores the answers to these questions and more, with Maker CTO Andy Milenius in conversation with Sonal Chokshi and a16z crypto partner Jesse Walden. Here are just two quotes from our jam session: Blockchains are an "open-access, permissionless, choose-your-own adventure story"; and smart contracts are an mp3-like "compression format" for scaling trust. Let the music begin! --- Please note that the a16z crypto fund is a separate legal entity managed by CNK Capital Management, L.L.C. (“CNK”), a registered investor advisor with the Securities and Exchange Commission. a16z crypto is legally independent and operationally separate from the Andreessen Horowitz family of fund and AH Capital Management, L.L.C. (“AHCM”). In any case, the content provided here is for informational purposes only, and does NOT constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. You should consult your own advisers as to legal, business, tax and other related matters concerning any investment. Furthermore, the content is not directed to any investor or potential investor, and may not be used or relied upon in evaluating the merits of any investment and must not be taken as a basis for any investment decision. No investment in any fund advised by CNK or AHCM may be made prior to receipt of definitive offering documentation and due diligence materials. Finally, views expressed are those of the individual a16z crypto personnel quoted therein and are not the views of CNK, AHCM, or their respective affiliates.
December 18, 2018
with Brian Armstrong (@brian_armstrong), Chris Dixon (@cdixon), and Sonal Chokshi (@smc90) Where are we, really, right now -- in terms of what we can/ can't do with crypto today? And what will it take to get from vision to mainstream reality? This episode of the a16z Podcast covers all this and more. It's based on a conversation that took place between Coinbase CEO and cofounder Brian Armstrong and a16z crypto general partner Chris Dixon, interviewed by a16z editor in chief Sonal Chokshi, at our at our annual Summit in November 2018 -- following a series of presentations that covered everything from early adoption, myths, and the global need for crypto; to crypto as seen through the lens of trust; to key terms and concepts that enable entirely new use cases on top of crypto. But what are the missing pieces needed to get us there? Is crypto is too much like a religion... and if so, how does one build a company, culture, community in such an intense environment? Where does the history of open source come in? And finally, what are some of the most interesting applications and trends in the space? --- Please note that the a16z crypto fund is a separate legal entity managed by CNK Capital Management, L.L.C. (“CNK”), a registered investor advisor with the Securities and Exchange Commission. a16z crypto is legally independent and operationally separate from the Andreessen Horowitz family of fund and AH Capital Management, L.L.C. (“AHCM”). In any case, the content provided here is for informational purposes only, and does NOT constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. You should consult your own advisers as to legal, business, tax and other related matters concerning any investment. Furthermore, the content is not directed to any investor or potential investor, and may not be used or relied upon in evaluating the merits of any investment and must not be taken as a basis for any investment decision. No investment in any fund advised by CNK or AHCM may be made prior to receipt of definitive offering documentation and due diligence materials. Finally, views expressed are those of the individual a16z crypto personnel quoted therein and are not the views of CNK, AHCM, or their respective affiliates. Please see https://a16zcrypto.com/disclosures/ for further information.
December 8, 2018
with Jeffrey Katzenberg, Meg Whitman (@MegWhitman), and Marc Andreessen (@pmarca) In this episode of the a16z Podcast, based on a discussion that took place at our annual a16z Summit, Marc Andreessen interviews Jeffrey Katzenberg -- formerly CEO and co-founder of DreamWorks SKG (and chairman of Walt Disney Studios during some of its biggest hits), now co-founder of tech holding company WndrCo -- and Meg Whitman -- former President and CEO of Hewlett Packard Enterprise, and now CEO of Quibi ("quick bites"), focused on short-form mobile video. Both Katzenberg and Whitman have known each other for years, but they resided in two different worlds -- entertainment and software -- which are now merging, not only through their current venture but more broadly, given fundamental shifts in the entertainment and media landscape. In this conversation, Andreessen probes them on where Hollywood comes in (or doesn't); the intersection of software and new media, including how content creation changes as platforms evolve; and what’s next for entertainment. Along they also touch on their unique working relationship, and leadership lessons learned...
November 21, 2018
with Boris Sofman (@bsofman), Dave Touretzky (@DaveTouretzky), and Hanne Tidnam (@omnivorousread) We're just now beginning to truly see the the first 'real' robots in the home, from Roombas to toys to companions to... well, much more. How are humans beginning to forge relationships with these robotic devices (/entities!) -- and how will those relationships develop? What do we learn as we begin to forge relationships and interact with robotic toys like Cosmo and Vector -- about robots, and about ourselves? And what do these learnings teach us about the possibility of adding a "personality wrapper" to new technologies? In this episode of the a16z Podcast, CEO and cofounder of Anki Boris Sofman, and Research Professor of Computer Science at CMU Dave Touretzky, discuss with a16z's Hanne Tidnam where we are in the human-robotic future, the history of robotics that has brought us here, and the next big breakthroughs -- in hardware, software, perception, navigation, and manipulation -- that will bring in the next waves of innovation for robots. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
November 19, 2018
with Adrienne Mayor (@amayor) and Hanne Tidnam (@omnivorousread) Is it possible that ancient Greeks and Romans dreamed of technological innovations like robots and artificial intelligence millennia before those technologies became realities? In this episode of the a16z Podcast, Adrienne Mayor, historian of science and author of the just released Gods & Robots: Myths, Machines, and Ancient Dreams of Technology, discusses with Hanne Tidnam the earliest myths around ideas of technology and even artificial life from the ancient world -- from the first imagined robot to walk the earth, to actual historical technological wonders of the ancient world such as mechanical flying doves or a giant miles-long parade of 10-foot-tall automatons. What do these early imaginings of technological invention tell us about human nature? And what can we take from understanding the deep roots of this mythology for the era of technology, today? Mayor is the 2018-19 Berggruen Fellow at the Center for Advanced Study in the Behavioral Sciences at Stanford, and author of The Amazons: Lives and Legends; Fossil Legends of the First Americans; and The Poison King, which was a National Book Award finalist.
November 17, 2018
with Stephanie Cohen and Martin Casado (@martin_casado) As chief strategy officer of Goldman Sachs (and former global head of financial sponsors M&A), Stephanie Cohen has seen it all when it comes to the ins and outs of M&A. And what it means to innovate from within, especially at a large company. Given Cohen's unique vantage point and nearly 20-year tenure at Goldman Sachs, Casado -- himself a veteran of both an acquisition (Nicira) and big company innovation (VMware) -- interviews Cohen in this episode of the a16z Podcast, on the ways that big companies navigate innovation... both inside and outside. How do they make the decision to build vs. buy? How does one diversify perspectives? And so on.  This episode is based on a fireside chat that originally took place at our annual a16z Summit event in November 2018.
November 5, 2018
with Prasad Akella, Paul Daughtery (@pauldaugh) and Frank Chen (@withfries2) What is different on that factory floor from Henry Ford to today? In this conversation, Prasad Akella, Founder and CEO of Drishti; Paul Daugherty, Chief Technology and Innovation Officer of Accenture, and author of the recently published Human + Machine: Reimagining Work in the Age of AI; and a16z operating partner Frank Chen, talk about how the introduction of automation from Henry Ford to now co-bots and AI all change the work we do in manufacturing and beyond. What are the skills that we’ll need in the future? What kinds of new information is available, and what new needs -- for dynamic adaptive processes, for example? What are the new tool chains and core (organizational and technical) habits of ML/AI-centric companies of the future?
October 20, 2018
with Jeff Jordan (@Jeff_Jordan), Yogi Roth (@YogiRoth), Zack Weiner and Hanne Tidnam (@omnivorousread) For decades, the increasing value of sports teams, rights, licenses and more have been fueled by sports media. But dollars follow eyeballs, and eyeballs -- at least on the traditional broadcast -- are going elsewhere. "If you don't know where you are going, you'll end up someplace else,” Yogi Berra once said. So where exactly are those eyeballs going, and what does that mean for the sports media industry, now that each and every one of us is an individual media platform? a16z General Partner Jeff Jordan, Yogi Roth, Pac-12 college football analyst and former athlete and coach, and Zack Weiner, co-founder and president of sports media platform Overtime -- in conversation with a16z's Hanne Tidnam -- talk all about the evolution of sports media and content, and what it means for how we will consume sports in the future. How will the way we watch sports fundamentally change? How this begin to affect the game itself? How are athletes thinking about brand in this new world of sports content?
October 8, 2018
The period from 2000-2016 was one of the best of times and worst of times for tech and the Valley (dotcom, financial crisis, Google IPO, Facebook founded, unprecedented growth, and so on), and John Hennessy -- current chairman of Alphabet, also on the boards of Cisco and other organizations -- was the president of Stanford University during that entire time. Given this vantage point, what are his views on Silicon Valley (will there ever be another one, and if so where?); the "Stanford model" (for transferring IP, and talent, into the world); and of course, on education (and especially access)? Hennessy also co-founded startups, including one based on pioneering microprocessor architecture used in 99% of devices today (for which he and his collaborator won the prestigious Turing Award)... so what did it take to go from research/idea to industry/implementation? General partners Marc Andreessen and Martin Casado, who also founded startups while inside universities (Netscape, Nicira) and led them to successful exits (IPO, acquisition by VMWare), also join this episode of the a16z podcast with Sonal Chokshi to share their perspectives. But beyond those instances, how has the overall relationship and "divide" between academia and industry shifted, especially as the tech industry itself has changed... and perhaps talent has, too? Finally, in his new book, Leading Matters, Hennessy shares some of the leadership principles he's learned -- and instilling through the Knight-Hennessy Scholars Program -- offering nuanced takes on topics like humility (needs ambition), empathy (without contravening fairness and reason), and others. What does it take to build not just tech, but a successful organization? image credit: Jitze Couperus / Flickr
September 27, 2018
with Shannon (Stubo) Brayton (@sstubo), Margit Wennmachers (@wennmachers), and Sonal Chokshi (@smc90) One of the company building topics that’s surprisingly mystifying is PR -- and only surprising since so much of the strategy and tactics behind public relations are actually hidden from public view. We've tried demystifying the topic in an ongoing series, covering everything from "the why, how, and when" of PR" and leaders building a personal brand to crisis communications. But the most frequently asked question startup founders, especially technical ones, have is how to manage a PR agency -- from when to bring one in and the mechanics of onboarding and engaging with them; to key acronyms to know in the process of doing so (what's an AoR? RFP? GA?); to what are the ideal configurations for the who-what-where of in-house vs. agency PR. So this episode of the a16z Podcast provides perspectives from both sides of the table (in-house vs. agency, big company vs. startup) for what it takes, featuring PR legends and veterans Shannon (Stubo) Brayton, chief marketing officer at LinkedIn (formerly at OpenTable and formerly vice president of corporate communications at eBay) and Margit Wennmachers, operating partner at Andreessen Horowitz who heads up the marketing function (and who co-founded and later sold The Outcast Agency), in conversation with Sonal Chokshi. It's not dictation -- whether from company to agency, or agency to reporter, or PR to internal stakeholders -- there's a lot of strategic thinking involved even with seemingly incidental things. And... it's a leap of faith.
September 25, 2018
with Michael Ovitz (@michaelovitz), Ben Horowitz (@bhorowitz), and Hanne Tidnam (@omnivorousread) When Michael Ovitz co-founded the Hollywood talent agency Creative Artists Agency (CAA), he turned a number of the entertainment industry's well-entrenched traditions on their head. The origin story of a16z (not coincidentally!) is not that dissimilar. So in this episode of the a16z Podcast, Ovitz and a16z co-founder Ben Horowitz talk with Hanne Tidnam about Ovitz' just-released book, Who is Michael Ovitz? -- and about how CAA transformed the power equation in Hollywood. The conversation covers everything from the history of the entertainment business -- the days of vaudeville and the Jack Warners and William Foxes and Jurassic Parks -- to what strategies guided the differentiation of the new kids on the block. There's lessons for other founders here, too, about culture, negotiation, and more.
September 24, 2018
with Fred Wilson (@fredwilson) and Chris Dixon (@cdixon) There's all sorts of interesting tech trends happening right now, including AI, VR/AR, self-driving cars and drones (as well as interesting stuff happening in verticals like healthcare and finance) -- and there's a lot also happening in seemingly more "mature" tech revolutions, such as mobile and cloud. But where are we now, really, with these shifts... and how does that inform how we think about the next couple decades? And does a framework like Carlota Perez's -- as outlined in Technological Revolutions and Financial Capital: The Dynamics of Bubbles and Golden Ages and summarized by venture capitalist and longtime internet investor Fred Wilson (of Union Square Ventures) -- fully apply when it comes to software? Because, argues Chris Dixon (general partner on a16z crypto), software "has so much more plasticity, ability to adapt, ability to evolve" that unlike hardware, "the core itself will also dramatically change... not just the apps around it". The total economic value that will be unlocked with the software revolution, observes Wilson, should be orders of magnitude bigger than what we saw with manufacturing for sure. But just how much internet innovation is actually powering true disruption (i.e., is more than just a sustaining innovation, to use Clayton Christensen's terminology)? How do new business models change everything? Dixon and Wilson consider all this and more in this hallway-style episode of the a16z Podcast, where we recorded the two having a think-aloud conversation about everything from the history of the internet and startups, the evolution of capital and infrastructure, to the advent of crypto. How do they they both define "decentralized", what do they think of dApps, and where do NFTs and "crypto goods" come in?? One thing's for sure: It's the most interesting time they've both ever seen in over 30 years of internet work, life, and play. Please note that the a16z crypto fund is a separate legal entity managed by CNK Capital Management, L.L.C. (“CNK”), a registered investor advisor with the Securities and Exchange Commission. a16z crypto is legally independent and operationally separate from the Andreessen Horowitz family of fund and AH Capital Management, L.L.C. (“AHCM”).  In any case, the content provided here is for informational purposes only, and does NOT constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. You should consult your own advisers as to legal, business, tax and other related matters concerning any investment.
September 18, 2018
with Benedict Evans (@BenedictEvans) and Steven Sinofsky (@SteveSi) In another of our hallway conversation episodes, Benedict Evans and Steven Sinofsky talk all about Tesla — and more broadly, the nature of disruption overall. How disruptive is Tesla really, and what exactly are they disrupting — from the dashboard to car makers to vendors to energy source to autonomy overall? The tech industry is littered with leading innovators... who nonetheless failed to be the dominant leader in the end. So the question should be, is this new thing fundamentally difficult for the incumbent to do, and how does it relate to market dominance? Which of these things are important in order for Tesla to be the new BMW or the new GM? Looking back at other examples historically (Microsoft, GM's Saturn Brand, and of course the iPhone), what kind of disruption matters most for market dominance? And what is the long view of how software is eating transportation?
September 14, 2018
with Benedict Evans (@BenedictEvans) and Steven Sinofksy (@StevenSi) In this hallway-style conversation episode of the a16z Podcast, Benedict Evans and a16z board partner Steven Sinofsky discuss Apple’s September 2018 keynote event and share their thoughts on the new innovations -- and lessons -- that really matter. With something that’s gone from toy to phone to fashion item -- and just pivoted to a health monitor that can literally save lives -- where are we now? How closely aligned is health to the overall value proposition, and what are some of the characteristics of how Apple innovates as a company as a whole... from components and building blocks to how it all comes together? image: Integrated Change/ Flickr(CC 2.0)
September 8, 2018
with Steven Johnson (@stevenbjohnson), Chris Dixon (@cdixon), and Sonal Chokshi (@smc90) There's a lot of research and writing out there on "thinking fast" -- the short-term, gut, instinctual decisions we make, biases we have, and heuristics we use -- but what about for "thinking slow" -- the long-term decisions we make that both take longer to deliberate and have longer spans of impact on our lives... and the world? Because we're not only talking about decisions like who to marry (or whether to move) here; we're also talking about decisions that impact future generations in ways we as a species never considered (or could consider) before. But... why bother, if these decisions are so complex, with competing value systems, countless interacting variables, and unforeseeable second- and third-order effects? We can't predict the future, so why try? Well, while there's no crystal ball that allows you to see clearly into the future, we can certainly try to ensure better outcomes than merely flipping a coin, argues author Steven B. Johnson in his new book, Farsighted: How We Make the Decisions That Matter Most. Especially because the hardest choices are the most consequential, he observes, yet we know so little about how to get them right. So in this episode of the a16z Podcast, Johnson shares with a16z crypto general partner Chris Dixon and a16z's Sonal Chokshi specific strategies -- beyond good old-fashioned pro/con lists and post-mortems -- for modeling the deliberative tactics of expert decision-makers (and not just oil-company scenario planners, but also storytellers). The decisions we're talking about here aren't just about individual lives and businesses -- whether launching a new product feature or deciding where to innovate next -- they're also about even bigger and bolder things like how to fix the internet, or what message to send aliens with outcomes spanning centuries far into the future. But that's where the power of story comes in again. * * * The content provided here is for informational purposes only, and does not constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. Please see https://a16zcrypto.com/disclosures/ for further information.
September 6, 2018
with Jeff Jordan (@Jeff_Jordan), Cal Turner Jr., and Hanne Tidnam (@omnivorousread) The "death of retail" in the face of e-commerce and tech disruption is a very real phenomenon, but what about the flip side of that story -- that is, retail thriving despite all odds? Enter Dollar General, a multi-billion-dollar success story of the U.S. chain with 14,000 brick-and-mortar dollar stores. So in this episode of the a16z Podcast, general partner Jeff Jordan -- who was formerly an SVP for The Disney Stores (and has written much about declining malls, competing with Amazon, and the tipping point for ecommerce, among other things) -- with Hanne Tidnam interviews Cal Turner, Jr., the CEO of Dollar General and author of the new book, My Father's Business: The Small-Town Values That Built Dollar General into a Billion-Dollar Company. How did Dollar General go from the Great Depression to nearly filing for bankruptcy to IPO and entering the Fortune 500? It turns out, the journey -- not unlike startups and successful big companies -- is a case study in focus, focus, focus... whether it was pricing (natch) or inventory or a focus on customers or simply (but not so simply!) focusing on one's "true north".
August 25, 2018
with Martin Casado (@martin_casado), Andrew Chen (@andrewchen), Russ Heddleston (@rheddleston), and Hanne Tidnam (@omnivorousread) What happens when the bottoms up, organic growth usually associated with consumer companies starts to go.... enterprise? Part of our continuing podcast series (you can listen to part one on user acquisition and part two on engagement/retention) on growth, this episode explores the increasing trend of enterprise growth shifting to be more "bottoms up" -- with a16z general partners Martin Casado and Andrew Chen, and DocSend CEO and co-founder Russ Heddleston, in conversation with Hanne Tidnam. So what exactly does more bottoms up growth for enterprise look like? And then how does organic growth map into the direct sales model we traditionally see in enterprise? How does it affect company building overall? What changes in how we evaluate growth, what do we look at... and how can those two different models work best together?
August 21, 2018
with Devon Zuegel (@devonzuegel), Denis Nazarov (@iiterature), and Jesse Walden (@jessewldn) The open source movement enabled so much in computing, including the collaborative building of libraries -- that is, building blocks of code that developers could combine together to build applications. But as these applications grew to massive scale, those libraries ended up being somewhat asymmetrical for "nights-and-weekend" developers (compared to say, the disproportionate resources of a large company with billions of users and big data). Blockchains, however -- enabled by cryptotokens that align incentives among stakeholders -- shift open source development from libraries, to the creation of shared, open, permissionless services. Instead of being siloed and repetitively produced as if from the industrial factory era, any smart contract developed on Ethereum becomes a shared service that can interact with any other service... incentivizing developers to improve on existing services, build on top of them, and enable combinatorial innovation at greater scale than ever before. But if decentralized networks are to win the third era of the internet, how will we resolve challenges such as single-purpose services (another form of consolidation), community conflicts, and other issues? In this video, freelance software engineer (and blockchain app developer) and writer (and urban watcher) Devon Zuegel guest-interviews a16z crypto partners Denis Nazarov and Jesse Walden, the co-founders of Mediachain Labs (which was acquired by Spotify in 2017). They draw on their past experiences leading open source development of a decentralized media attribution protocol for connecting creators to their audience, and what the implications of "services vs. libraries" could be for creatives now. And what about identity, stablecoins and crypto finance, and more? Finally, they extend their previous analogy of cities and network effects and how it fits the idea of libraries vs. services in crypto. * * * Please note that the a16z crypto fund is a separate legal entity managed by CNK Capital Management, L.L.C. (“CNK”), a registered investor advisor with the Securities and Exchange Commission. a16z crypto is legally independent and operationally separate from the Andreessen Horowitz family of fund and AH Capital Management, L.L.C. (“AHCM”).  In any case, the content provided here is for informational purposes only, and does NOT constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. You should consult your own advisers as to legal, business, tax and other related matters concerning any investment. Furthermore, the content is not directed to any investor or potential investor, and may not be used or relied upon in evaluating the merits of any investment and must not be taken as a basis for any investment decision. No investment in any fund advised by CNK or AHCM may be made prior to receipt of definitive offering documentation and due diligence materials. Finally, views expressed are those of the individual a16z crypto personnel quoted therein and are not the views of CNK, AHCM, or their respective affiliates.  Please see https://a16zcrypto.com/disclosures/ and https://a16zcrypto.com/disclaimers for further information.
August 9, 2018
with Andrew Chen (@andrewchen), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90) Once you have users, how do you keep them engaged, retain them, and even "resurrect" or re-engage them? That's the focus of this episode of the a16z Podcast, which continues our series on the basics of growth from user acquisition to engagement and retention -- covering, as always, key metrics and how to think about them. Especially as many products and platforms evolve over time, so do the users, some of whom may even use the product in different ways... so what does that mean for engagement, and how can startups analyze their users? "Show me the cohorts!" may be the new "show me the money"...  Featuring a16z general partners Andrew Chen and Jeff Jordan, in conversation with Sonal Chokshi, the discussion also covers everything from how network effects come in to play (is there really a magic number or "aha" moment for a product?) to who are the power users (and the power user curve for measuring, finding, and retaining them). Because at the end of the day, you don't want a leaky bucket that you're constantly trying to fill up. That doesn't work, and definitely won't scale. --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
August 9, 2018
with Andrew Chen (@andrewchen), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90) Growth is one of the most top of mind questions for entrepreneurs building startups of all kinds (and especially consumer ones) -- but how does one go beyond a mindset of "growth hacking" to thinking about growth more systemically and holistically? What are the key metrics to know; why; and how? This episode of the a16z Podcast -- one of two in a series -- focuses on the user acquisition aspect of growth, followed by engagement and retention in the next episode. Featuring a16z general partners Andrew Chen and Jeff Jordan, in conversation with Sonal Chokshi, the discussion also covers the nuances of paid vs. organic marketing (and the perils of blended CAC); the role of network effects; where does customer lifetime value (LTV) come in; and much more. Because at the end of the day, businesses don't grow themselves... --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
August 4, 2018
with Ben Horowitz (@bhorowitz) and Sharon Chang (@sychang) What does it really take to start a startup (or work at one)? In this episode of the a16z Podcast -- based on a Q&A with Ben Horowitz as part of an event hosted by a16z's Technical Talent and People Practices team for a16z portfolio company summer interns 2018 -- Ben shares quick thoughts and advice geared towards those early in their tech careers. The conversation covers everything from how to know what kind of company to join early (or when to strike out on one's own); the major platform shifts we should anticipate going forward; and founding (as well as exit) stories, like Microsoft’s acquisition of Github. What was the moral of that story for him, and for the industry?... this short a16z Bytes episode shares a glimpse into (some of) those "earned secrets". --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
August 1, 2018
with Denis Nazarov (@iiterature), Jesse Walden (@jessewldn), Ali Yahya (@ali01), and Devon Zuegel (@devonzuegel) Cryptonetworks are often compared to firms, people, or even coral reefs -- but, observes a16z crypto partner Ali Yahya, they might be much more similar to cities. Where does that analogy fit, and where does it break down? And what can we learn from how cities both emerge from the bottom up and are motivated by a top down vision/design  and apply to open source networks such as those in crypto? In this episode of the a16z Podcast -- guest hosted by freelance software engineer (and blockchain app developer) and writer (and urban watcher) Devon Zuegel -- a16z crypto partners Denis Nazarov, Jesse Walden, and Yahya share their thoughts on "rough consensus"; shared myths and beliefs; modularity vs. monolithic design; and the rivers and riverbeds that people build cities and code around. At the end of the day, it's all about mass coordination at scale... but what are the incentives for building the infrastructure and ecosystem, for running experiments but also determining governance as well? *** Please note that the a16z crypto fund is a separate legal entity managed by CNK Capital Management, L.L.C. (“CNK”), a registered investor advisor with the Securities and Exchange Commission. a16z crypto is legally independent and operationally separate from the Andreessen Horowitz family of fund and AH Capital Management, L.L.C. (“AHCM”).  In any case, the content provided here is for informational purposes only, and does NOT constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. You should consult your own advisers as to legal, business, tax and other related matters concerning any investment. Furthermore, the content is not directed to any investor or potential investor, and may not be used or relied upon in evaluating the merits of any investment and must not be taken as a basis for any investment decision. No investment in any fund advised by CNK or AHCM may be made prior to receipt of definitive offering documentation and due diligence materials. Finally, views expressed are those of the individual a16z crypto personnel quoted therein and are not the views of CNK, AHCM, or their respective affiliates.  Please see https://a16zcrypto.com/disclosures/ and https://a16zcrypto.com/disclaimers/ for further information.
August 1, 2018
with Chris Dixon (@cdixon), Ali Yahya (@ali01), and Devon Zuegel (@devonzuegel) “Show me the incentive and I'll show you the outcomes.” At the end of the day, observes a16z crypto general partner Chris Dixon, Satoshi's whitepaper [the original bitcoin paper outlining a peer-to-peer decentralized network and blockchain sans centralized third parties] is nine pages of incentives. It's the kind of incentive design that you can use to build many other things on the internet (which itself is driven by very simple core protocols and could even upgrade itself as a result). But only with the right incentives (and alignment of those incentives among different entities), of course. Which is where cryptonetworks come in -- especially since they don't rely on hardware buildout (as with earlier generations of internet deployment), but rather on software (which is essentially just logic, the kind of building block you can use to build countless other things). The breadth of possibilities is endless. This means that platforms and networks (and operating systems, for that matter) can spend less time, energy, money, and frankly, suffering due to fighting -- thanks to distorted business models that lead them to extract value from users and compete among complements (vs. substitutes/better alternatives). The internet-native business models baked into crypto, however, could lead to greater competition and better options for users. But what are the missing building blocks, that can help make such networks more iterated games vs. one-off prisoner's dilemmas? And what will it take for these networks to truly reach web-scale, as it's still just the beginning? Because decentralization is the means to an end -- not the end in and itself -- observes a16z crypto partner Ali Yahya, so what do we need to build next to get there? In this episode of the a16z Podcast (guest hosted by freelance software engineer and writer Devon Zuegel), Dixon and Yahya share their thoughts on where we've been, and where we're going with the internet. Please note that the a16z crypto fund is a separate legal entity managed by CNK Capital Management, L.L.C. (“CNK”), a registered investor advisor with the Securities and Exchange Commission. a16z crypto is legally independent and operationally separate from the Andreessen Horowitz family of fund and AH Capital Management, L.L.C. (“AHCM”).  In any case, the content provided here is for informational purposes only, and does NOT constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. You should consult your own advisers as to legal, business, tax and other related matters concerning any investment. Furthermore, the content is not directed to any investor or potential investor, and may not be used or relied upon in evaluating the merits of any investment and must not be taken as a basis for any investment decision. No investment in any fund advised by CNK or AHCM may be made prior to receipt of definitive offering documentation and due diligence materials. Finally, views expressed are those of the individual a16z crypto personnel quoted therein and are not the views of CNK, AHCM, or their respective affiliates.  Please see https://a16zcrypto.com/disclosures/ and https://a16zcrypto.com/disclaimers/ for further information.
July 20, 2018
with Elad Gil (@eladgil) and Chris Dixon (@cdixon) There's a lot of knowledge out there -- and networks of talent (especially in Silicon Valley) -- on what to do in the early stages of a company, going from 0 to 1, and even in going from 1 to 100... but what about beyond that? It's not as simply linear as merely doubling or tripling resources and org structures; it's actually much more complex on many levels, communication to coordination. Because with great scale comes great complexity... and many, many more places for things to break down. So how should founders/CEOs of growing tech startups think about everything from hiring (including key executives) to product management (what is it, really, beyond common myths/misconceptions around the role?) to thinking about late-stage financing, M&A, and other key aspects of building a company? This episode of the a16z Podcast shares both specific answers to -- and general mindsets for thinking about -- these questions. Chris Dixon, general partner on a16z crypto, interviews Elad Gil, investor/advisor to numerous tech companies; co-founder of Color Genomics; formerly of Google and also co-founder and CEO of Mixer Labs (acquired by Twitter, where he also became a VP). He's the author of the new book, The High Growth Handbook, on scaling companies from 10 to 10,000 people. But the two also explore the growth -- and evolution -- of market and tech trends, including the continuation of mobile/cloud; machine learning (and silicon); crypto; and finally, longevity -- both in the near term and further out in the future. Should people -- and even companies for that matter -- really live longer?
July 17, 2018
with Katie Haun (@katie_haun), Robin Weisnman (@robinweisman), and Sonal Chokshi (@smc90) What’s going on, regulation-wise, in crypto? How should people who want to join a company or build something new in the space think about the regulatory environment? What to make of all the headlines, or the "alphabet soup" of agencies potentially involved in regulating crypto? This episode of the a16z Podcast shares principles -- as well as key players/acronyms to know -- for sorting the signal from the noise in the regulatory landscape for crypto. The experts in conversation with a16z editorial partner Sonal Chokshi include: Robin Weisman, who helped found and is a lobbyist for Coin Center, a nonprofit policy research and advocacy group for cryptocurrencies; and was formerly a director of government relations at Nasdaq; and Kathryn (Katie) Haun, who teaches crypto at Stanford Business School; is on the boards of Coinbase and HackerOne; is a former federal prosecutor with the U.S. Department of Justice, where she led their first digital currency task force and prosecuted a number of cases in the space; and was recently announced as general partner.  The discussion is based on a panel that originally took place at the “Intro to Crypto” event that Andreessen Horowitz and #Angels put on in April 2018. You can see other talks from this event -- including a video on the building blocks of crypto; as well as sessions on the big picture of decentralization to building companies in crypto, from people to code -- here. This panel also presented the below slide, which is referenced in (but is not necessary to follow) this episode: https://a16z.files.wordpress.com/2018/07/regulatorylandscape-acronyms-introtocrypto_a16z.png photo credit: Erin Brethauer
July 17, 2018
with Tina Bhatnagar (@tinab), Preethi Kasireddy (@iam_preethi), Lily Liu (@calilyliu), and Kim Milosevich (@kimbatronic) Whether it’s sharing the decision-making behind joining a crypto company to the perspectives of a passionate early adopter (or relative latecomer), this episode of the a16z Podcast -- based on a panel from the “Intro to Crypto” event that Andreessen Horowitz and #Angels put on in April 2018 -- covers what it takes to build companies in crypto, from people to code. You can find other sessions from the event, covering the building blocks of crypto to decentralization to the regulatory landscape, here. Why crypto? What was the biggest surprise in the space? Do the same skills from other domains apply? This discussion, moderated by Kim Milosevich, explores these questions with Coinbase VP of Operations Tina Bhatnagar; CEO and founder of TruStory Preethi Kasireddy; and Lily Liu, co-founder at Earn.com. photo credit: Erin Brethauer --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
July 17, 2018
with Chris Dixon (@cdixon), Elizabeth Stark (@starkness), and Jessica Verrilli (@jess) Why does decentralization matter? This episode of the a16z Podcast -- based on a discussion that first took as part of an “Intro to Crypto” event that Andreessen Horowitz and #Angels put on in April 2018 -- explores the whys and the hows, from the history of the internet to the culture of crypto communities today. Chris Dixon (now of a16z crypto) and Elizabeth Stark (CEO and co-founder of Lightning Labs) share their thoughts with moderator Jessica Verrilli (a founding partner of #Angels, former vice president of corp dev and strategy at Twitter, and now general partner at Google Ventures). You can see other talks from this event -- including a video on the building blocks of crypto; a podcast on the regulatory landscape; and thoughts on building companies in crypto, from people to code -- here. The content provided here is for informational purposes only, and does not constitute an offer or solicitation to purchase any investment solution or a recommendation to buy or sell a security; nor it is to be taken as legal, business, investment, or tax advice. In fact, none of the information in this or other content on a16zcrypto.com should be relied on in any manner as advice. Please see https://a16zcrypto.com/disclosures/ for further information. photo credit: Erin Brethauer --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments and certain publicly traded cryptocurrencies/ digital assets for which the issuer has not provided permission for a16z to disclose publicly) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.
July 13, 2018
with Jorge Conde (@jorgecondebio), David Reich, and Hanne Tidnam (@omnivorousread) Trying to reconstruct the deep past of ancient humans out of present-day people has until now been like trying to reconstruct a bomb explosion in a room from bits of shrapnel, says David Reich, Professor of Genetics at Harvard Medical School and author of the new book, Who We Are and How We Got Here: Ancient DNA and the New Science of the Human Past. But technological advances and new tools available only in the last few years have suddenly revolutionized this field, opening up an entirely new window into the past as well as our present humanity. This conversation, with a16z bio general parter Jorge Conde, and Hanne Tidnam, dives into this new scientific revolution of the study of the ancient genome. Beginning with the so-called "black hole" of Mitochondrial Eve to the most revelatory discoveries from new knowledge and scientific tools, this episode of the a16z Podcast delves into the ways archaic humans and ancient DNA tell us not just about our biology, but about ourselves. image: Ben Casey, Wikimedia Commons
July 13, 2018
with Ken Coleman, Ben Horowitz (@bhorowitz), and Michel Feaster (@michelfeaster) Everyone talks about the importance of mentorship in our professional development, whether it's networking to broaden career opportunities or learning from someone more experienced. But how does one break into an industry without established contacts or prior exposure? Are things different if mentors/mentees come from different backgrounds? If you're already more established in your career, how can you help up-and-comers... and actually, how could mentees help mentors, too? This episode of the a16z Podcast aims to answer these questions, and more. It's based on a networking event held by Andreessen Horowitz in May 2018 and featuring a Q&A moderated by Usermind CEO and co-founder Michel Feaster in conversation with a16z co-founder and general partner Ben Horowitz (also HER mentor); and Ken Coleman (also HIS mentor). Beginning with their personal journeys and ending with advice for others, they talk about their entry points into the tech world to how mentorship continues to play a role in their careers... both as mentors, and mentees. photo credit: Chris Lyons
July 7, 2018
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson) The rise of zero-sum thinking -- which has come snapping back recently -- slows and even halts progress, observes Marc Andreessen. Because you're then dividing up a smaller piece, adds Ben Horowitz, instead of growing the pie altogether. This is true not just in economics, politics, and tech, but also in business relationships (and life), too. And speaking of such relationships, how does the partnership between Ben and Marc work, more than two decades later, how has it changed through different types of organizations -- and is there anything startup co-founders (and other colleagues) can take away from it? Where do they find the creative inspiration, information, and influences for new ideas? And then, more broadly, how do they think about tech change... including jobs, automation, AI in general? This episode of the a16z Podcast covers these questions and much more. It's based on a fireside chat that took place at our annual a16z Summit event in November 2017 (which brings together large companies, finance investors, academics, and startups to talk all things innovation), and is moderated by author Steven B. Johnson -- who has written numerous magazine articles, 11 books so far (including Where Good Ideas Come From), and also hosted the PBS series “How We Got to Now”. Incidentally, those are the de facto themes for this conversation, which arcs from past to present to future -- taking us from blinking cursors to dashboards to screens and beyond.
June 22, 2018
Compensation is a topic near and dear to everyone’s heart… but what does “compensation” fully mean — and what does it include, what doesn’t it include? How do entrepreneurs compete for talent in an intensely competitive environment, while balancing their startup’s affordability considerations? This wide-ranging episode of the a16z Podcast (based on an event held for entrepreneurs at Andreessen Horowitz earlier this year) covers all things compensation — from philosophical questions such as how to get to alignment around your company’s compensation philosophy to details such as the tradeoffs between RSUs vs. stock options. The discussion includes Steve Cadigan, talent advisor and cofounder at ISDI Digital University; Thanh Nguyen, Executive Director at Connery Consulting; Greg Loehmann, principal at Compensia; and a16z partner Shannon Schiltz, who heads up a16z’s human resources, tech talent, and people practices operation.
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