The Human Upgrade: Biohacking for Longevity & Performance
The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Fish Oil Doesn’t Work? Anti-Aging Butterflies, the Ancient Brain Focus Switch, and the Best Brain Diet : 1491
Does fish oil actually protect your brain, can your mindset slow aging, and what can butterflies teach us about longevity? Dave Asprey unpacks the week’s biggest biohacking breakthroughs.
Jun 26
13 min
The 'Secret Sauce' To A 10/10 Morning Routine  : 1490
5:38 PMClaude responded: Jeff Boyd, founder of MTE, joins Dave Asprey to break down why conventional energy drinks are sabotaging your cortisol, sleep, and gut health, and how a full-s…Jeff Boyd, founder of MTE, joins Dave Asprey to break down why conventional energy drinks are sabotaging your cortisol, sleep, and gut health, and how a full-spectrum stack of adaptogens, nootropics, and prebiotics delivers clean, foundational energy without the crash.
Jun 25
38 min
The Biohacking Secrets of Dubai | Dr. Elie Abirached : 1489
12:24 PMClaude responded: Childhood trauma forged in war becomes the foundation for a biohacking philosophy built around nervous system mastery and intentional living.Childhood trauma forged in war becomes the foundation for a biohacking philosophy built around nervous system mastery and intentional living.
Jun 23
25 min
It's Weird, But It Turns On Your Body's Anti-Aging Switch Fast : 1487
Your body's built-in mitochondrial cleanup process (mitophagy) is being silently suppressed by modern stress, eating habits, and aging, but you can reactivate it through fasting, high-intensity exercise, cold exposure, NAD+ supplementation, and compounds like urolithin A and spermidine.
Jun 21
15 min
Sugar-Free Backlash, Taurine Fail, Copper Brain Therapy, Childhood Biohacking, Strength Training : 1488
This week Dave breaks down five studies that challenge what you think you know about copper and Alzheimer's, sugar-free diets, strength training, childhood brain development, and taurine, and why the label is almost never the whole story.
Jun 19
11 min
BDNF Superpowers Through MDMA and Ketamine | Dr. Dave Rabin   : 1486
11:13 AMClaude responded: A board-certified psychiatrist and neuroscientist breaks down why ketamine and MDMA therapy repair trauma at the epigenetic level, why most antidepressants are…A board-certified psychiatrist and neuroscientist breaks down why ketamine and MDMA therapy repair trauma at the epigenetic level, why most antidepressants are keeping people sick, and why psychedelic medicine is the biggest breakthrough in the history of psychiatry.
Jun 18
1 hr 1 min
The Skin Mistakes That Age You Fast and Kill You Slow | Dr. Michael Christopher  : 1485
2:30 PMClaude responded: Dermatologist Dr.Dermatologist Dr. Michael Christopher exposes the melanoma detection gap most doctors don't know exists and shares the tools, habits, and skin science that can save your life.
Jun 16
44 min
Just 1 Gram Activates Your Deep Focus Switch (Take THIS) : 1484
Vitamin C — not willpower — is the missing key to effortless focus, because your brain can't produce the neurotransmitters it needs without it, and learning to supplement and absorb it correctly can eliminate mental fatigue at its biological root.
Jun 14
11 min
World Cup, Sunscreen, Hair Regrowth, Caffeine Chewing Gum, and more...  : 1483
GLP-1 drugs are moving aging clocks, the FDA finally caught up to Europe on sunscreen, and a DNA sugar may regrow hair — Dave Asprey breaks down six stories that all come back to the same question: what is this molecule actually doing inside your body?
Jun 12
11 min
Brain Fog, Memory Loss, and Alzheimer's Prevention | Dr. Majid Fotuhi  : 1482
A Johns Hopkins and Harvard-trained neurologist with 37 years of experience reveals why your brain is physically shrinking right now, why brain fog and cognitive decline are always treatable, and exactly what to do about it.
Jun 11
1 hr 19 min
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