The Human Upgrade: Biohacking for Longevity & Performance
The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
400mg Before Bed Improves Deep Sleep by 1700% : 1557
I slept 8 hours a night and got 5 minutes of deep sleep, and no doctor could help me.
Oct 18
13 min
John Gray: Why Men Stop Wanting Their Wives : 1556
John Gray explains how testosterone and estrogen drive male-female relationship dynamics, from emotional communication and conflict resolution to sexual polarity and recovering from public criticism.
Oct 16
1 hr 45 min
Sleep Expert: 80% of Sleep Problems Come From THIS : 1555
Sleep expert Dr. Michael Breus joins Dave Asprey to reveal why fear and anxiety may be driving your sleep problems, how chronotypes and circadian rhythms affect sleep quality, and practical strategies to fall asleep faster, stay asleep longer, and wake up feeling more rested.
Oct 15
40 min
The Science Behind Joint and Cartilidge Repair : 1554
Host Dave Asprey sits down with research microbiologist Kiran Krishnan to explore groundbreaking research on cartilage regeneration, joint repair, nitric oxide, vascular health, muscle growth, and how improving blood flow may help the body repair itself and maintain strength as it ages.
Oct 13
49 min
Your Brain Has a Focus Switch (Here's How to Turn It On) : 1553
Your focus depends on a norepinephrine and dopamine "switch" that chronic stress, bad sleep, and sitting all day drain, and you can turn it back on in about 20 minutes with morning light, movement, and a stack of L-tyrosine, caffeine, and L-theanine.
Oct 11
18 min
Infections & Cancer, Finasteride Side Effects, Blueberry Benefits, Vitamin D & Fertility, and CoQ10  : 1552
Dave Asprey breaks down five new health stories on infection-driven cancer risk, finasteride side effects, blueberries and polyphenols, vitamin D and male fertility, and why CoQ10 shows that a strong biological mechanism does not always translate into better outcomes.
Oct 9
11 min
How to Unlock Psychic Abilities to Know When You’ll Die : 1551
Dave Asprey and psychic medical intuitive Julie Ryan explore whether intuitive abilities can be trained, how they may relate to healing and consciousness, and what Julie says happens as people approach death.
Oct 8
1 hr 4 min
How to Live Healthier Without Obsessing Over Health  : 1550
Miranda Kerr joins Dave Asprey to explore how simplifying health around clean living, sleep, stress management, meditation, family, and intentional skincare can create a more sustainable approach to wellness.
Oct 6
51 min
It's Boring, But It Slashed ALL My Visceral Fat In My 50s : 1549
Dave Asprey shares the five hacks that helped him lose over 100 pounds and feel decades younger, from inventing butter coffee in Tibet to eating more saturated fat, cutting anti-nutrients, intermittent fasting, and prioritizing nutrition over endless gym sessions.
Oct 4
19 min
Vagus Nerve Memory, Cat Cancer Genes, Inherited Intelligence, Mulberry Microbes, and Vitamin D  : 1548
Dave Asprey breaks down new research on vagus nerve stimulation and memory, feline cancer genetics, inherited cognitive ability, mulberries and the microbiome, and how magnesium changes vitamin D metabolism.
Oct 2
10 min
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