The Human Upgrade: Biohacking for Longevity & Performance
The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Every Way to Melt Visceral Fat FAST In 14 Minutes : 1545
Dave Asprey outlines six science-backed methods to melt visceral fat—ranging from high-protein eating and HIIT to cold exposure, weightlifting, quality sleep, and stress reduction—arguing that chronic stress is the root cause that must be addressed for lasting fat loss.
Sep 27
14 min
Ozempic Hair, GLP-1 Kids, Gut-Brain Anxiety, Food Additives, Taurine, and more : 1544
A roundup of five health stories — Novo Nordisk's interest in hair loss, nutritional deficiencies in kids on GLP-1s, stomach-brain synchronization and mental health, food preservatives linked to heart disease, and taurine's stress-protective effects in rats — closing with a reminder to audit the hidden downsides of any health intervention you're already doing.
Sep 25
14 min
The Best Singular Hack To Change EVERYTHING About Your Life : 1543
Dr. Robert Waldinger shares findings from the 85-year Harvard Study of Adult Development revealing that the quality of our relationships—not wealth, fame, or power—is the single greatest predictor of health, happiness, and longevity, and offers practical strategies for building "social fitness" at any life stage.
Sep 24
1 hr 13 min
15g Every Morning for Anti-Aging Mitochondria  : 1541
Dave Asprey and Catharine Arnston explore how spirulina and chlorella may support mitochondrial function, cellular energy, detoxification, brain health, and healthy aging.
Sep 22
58 min
I Wasted 10 Years Stuck With Brain Fog Until I Learned This : 1540
A mold illness survivor explains how toxic mold in your home and body causes chronic brain fog, fatigue, and inflammation — and lays out a step-by-step plan to identify the source, remediate your environment, and detox what your body has already absorbed.
Sep 20
20 min
Teal Swan - Beyond the Veil of Ego, AI & Wisdom  : 1539
Dave Asprey sits down with spiritual teacher Teal Swan to explore narcissism, betrayal, extrasensory perception, the nature of ego, divine masculine and feminine energy, and whether humanity can heal its deepest wounds.
Sep 18
1 hr 2 min
How to Hack Your Smell for Memory and Longevity WHILE YOU SLEEEP! : 1538
Dave Asprey and neurobiologist Dr. Michael Leon explore how your sense of smell influences memory, sleep, brain aging, and longevity, and why olfactory enrichment may be one of the most overlooked tools for protecting cognitive health.
Sep 17
54 min
Josh Duhamel on Nootropics, Peptides, and Testosterone at 53 : 1537
This episode is a wide-ranging conversation covering testosterone and hormone replacement therapy, peptides, biohacking, psychedelics and spirituality, parenting, and building a health/longevity business, with the hosts sharing personal experiences throughout.
Sep 16
55 min
The Peptide Secrets to a Youthful Face : 1536
Dave Asprey and Carolina Reis de Oliveira break down how senescent cells, menopause, hydration loss, and peptide science affect skin aging, and what the latest research suggests may help make skin function biologically younger.
Sep 15
55 min
What 36 Hours Without Sugar Does to Your Body : 1535
This episode walks through an hour-by-hour timeline of what happens in your body during 36 hours without sugar — from falling insulin and dwindling glycogen to fat burning, ketone production, autophagy, and hormonal reset — explaining how cutting sugar reverses insulin resistance and drives visible physical improvements.
Sep 13
12 min
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