The Human Upgrade: Biohacking for Longevity & Performance Podcast

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Eat These Foods + Spices for 8 Weeks To Get 3 Years Younger | Kara Fitzgerald  : 1461
Dr. Kara Fitzgerald reveals how a targeted diet and supplement protocol reversed biological age by over three years in eight weeks, then goes deep on the Yamanaka factor science that could make that just the beginning.
May 5
54 min
This 9,000-Year-Old Ritual Cleared 15 Years Of Brain Fog : 1460
Brain fog isn't a willpower problem — it's a stressed nervous system, and ancient heat rituals like infrared sauna and contrast therapy are the most effective ways to reset it.
May 3
14 min
Selfies Predict Cancer, Dirty Feed, Bone Vibration, and more...  : 1459
Dave Asprey breaks down five new research stories — from Finnish dirt playgrounds and exercise variety data to facial aging AI, bone-building wearables, and the raw milk H5N1 situation — and tells you exactly what to do with each one.
May 1
10 min
The Strangest Thing I Do Every Morning for 15 Minutes | Brad Pitzele  : 1458
Dave Asprey and Brad Pizzoli discuss how combining Exercise with Oxygen Therapy (EWOT) and red light therapy supercharges mitochondrial function, fights inflammation, and improves circulation to address chronic illness and slow aging.
Apr 30
48 min
How Beef Is Destroying Your Hormones – Cynthia Thurlow  : 1457
Nurse practitioner and women's health expert Cynthia Thurlow joins Dave Asprey to expose the hormonal, gut, and environmental root causes of perimenopause that mainstream medicine ignores, and the real solutions that give women their bodies, brains, and relationships back.
Apr 28
1 hr 4 min
Supercharge Your Immunity In 4 Weeks With THIS Ancient Fruit : 1456
Urolithin A researcher breaks down the science of immune aging, mitochondrial decline, and how a compound derived from pomegranates may restore the cellular cleanup process your body loses after 40.
Apr 26
11 min
Inside Kambo: Poison, Purging, and The People Who Swear By It : 1455
Kambo researcher and practitioner Caitlin Thompson breaks down the peptide science, risks, and remarkable healing potential behind frog venom ceremonies and why intentional suffering might be one of the most powerful biohacking tools you have never tried.
Apr 24
44 min
You've Been Getting Dumber Every Day Since You Turned 30 : 1454
Neuroscientist Dr. Tommy Wood breaks down the science of brain aging, cognitive decline, and the biohacking strategies you can use to build a sharper, more resilient mind at any age.
Apr 23
58 min
Jason Fung: 3 Rules to Lose 50 Pounds Without Ever Counting a Calorie  : 1453
You are not overeating because you lack willpower, you are overeating because you have been biologically and behaviorally programmed to, and this episode explains exactly how to stop.
Apr 21
1 hr
1 Cup Every Morning Helped Me Lose 100 Pounds (Drink THIS) : 1452
Everything you've been told about diet and exercise is wrong — here's how eating more fat, skipping breakfast, and ditching the gym helped one biohacker lose 100 pounds and turn back his biological clock by 20 years.
Apr 19
17 min
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