A Japanese village's daily breakfast of natto — rich in spermidine — triggers the Nobel Prize-winning cellular repair process of autophagy, reversing biological aging within 72 hours when combined with proper dosing, exercise, sleep, and diet.
Jul 12
14 min
Jordan Harbinger joins Dave Asprey to share how he talked his way out of two kidnappings and breaks down the psychology-driven systems — calendar blocking, pain-point habit hacks, and relationship-building — he uses to stay productive and charming under pressure.
Jul 10
1 hr 8 min
Dave Asprey sits down with Dr. David Perlmutter to explore how brain inflammation and microglial dysfunction drive Alzheimer's, Parkinson's, and other neurodegenerative conditions — debunking the amyloid hypothesis along the way and examining emerging treatments like GLP-1 drugs, 40 hertz light therapy, and lifestyle interventions.
Jul 9
53 min
Discover how a suppressed 1910 light therapy can restructure water inside your cells, boost mitochondrial energy, and reverse the damage caused by blue light and EMF exposure.
Jul 7
1 hr
Dave Asprey breaks down which legal focus compounds (caffeine+L-theanine, adaptogens, MCT oil, methylene blue, and especially creatine) actually boost brain energy and performance, and shows how to stack them for sustained, crash-free focus.
Jul 5
16 min
This episode covers new research on gut-derived acetate and brain health, GLP-1 side effects on smell and taste, toxoplasmosis prevalence, exercise's outsized mental health benefits, individual variation in processing plant phytonutrients, produce pesticide guidance, and the Unilever-Thorne acquisition — all tied together with a call to actually track your own biomarkers instead of just consuming health news.
Jul 3
10 min
Dave Asprey and Ben Azadi discuss metabolic health, covering carnivore diet experiments, cyclical ketosis, electrolytes, sleep optimization, and creatine, while trading practical biohacking tips and reflecting on building health platforms despite online criticism.
Jul 2
1 hr 2 min
3:45 PMClaude responded: Oxytocin researcher and triple board-certified OBGYN Dr.Oxytocin researcher and triple board-certified OBGYN Dr. Anna Cabeca joins Dave to expose what conventional medicine gets wrong about hormones, pleasure, and longevity, and how fixing your oxytocin, estrogen, and FSH levels can transform your health, your brain, and your relationships at any age.
Jun 30
54 min
Dave explains how age‑related drops in the mitochondrial cofactor NAD⁺—and overactivity of enzymes that destroy it—drive fatigue, brain fog, and degeneration, then lays out a protocol (diet, polyphenols, fasting, REHIT exercise, and NMN/NR supplementation) to rebuild NAD⁺ and slow aging
Jun 28
12 min
Does fish oil actually protect your brain, can your mindset slow aging, and what can butterflies teach us about longevity? Dave Asprey unpacks the week’s biggest biohacking breakthroughs.
Jun 26
13 min
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