This Week in Microbiology
This Week in Microbiology
Vincent Racaniello
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This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.
227: The light and dark sides of the fungal world
TWiM presents an episode for mycophiles: how bacteria disarm mushroom pathogens, and the role of the CARD9 protein in protective immunity against pulmonary cryptococcosis. Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt and Michele Swanson Become a patron of TWiM. Links for this episode: Black in Microbiology How bacteria disarm mushroom pathogens (PNAS) A bacterial battleground (Science) CARD9 needed for fungal defense (mBio) OneHealth: Fungal pathogens (AAM) Image credit Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to
Oct 12
48 min
226: Two microbes you might not know
TWiM presents two unusual microorganisms, Erysipelothrix rhusiopathiae, heard by Elio in an episode of Doc Martin, and Roseomonas mucosa, which is being used to treat atopic dermatitis.
Sep 24
1 hr 9 min
225: Lag phase is no slouch
The TWiM team explores how delivery of an enzyme into competitor cells leads to synthesis of (p)ppApp, depletion of ATP, deregulation of metabolic pathways, and cell death, and a refinement of our typical view of bacterial lag phase as a period of nonreplication.
Sep 11
1 hr 3 min
224: One hundred million year old bacteria
The TWiM team reveals the genetic mysteries of the Dead Sea Scrolls from sequencing of DNA, and 100 million year old living bacteria recovered from marine sediments.
Aug 27
1 hr 15 min
223: The smell of soil
The TWiMmers explore detection of SARS-CoV-2 on surfaces in an ophthalmology examination room, the ability of stressed populations of Yersinia bacteria to survive antimicrobial treatment within host tissues, and how volatile organic chemicals produced by soil microbes attract arthropods which in turn disperse bacterial spores. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Become a patron of TWiM. Links for this episode SARS-CoV-2 RNA in ophthalmology room (JAMA Ophth) Stressed Yersinia survive doxycycline treatment (mBio) Volatiles, a soil arthropod, and Streptomyces spore dispersal (Nature) Image credit Send your microbiology questions and comments (email or recorded audio) to  
Aug 14
1 hr 1 min
222: Biosensors in bacteria
Mark Martin joins TWiM to describe nano-sized parasitic bacteria that inhabit humans, and the construction of whole-cell biosensors for detecting arsenic in drinking water.
Jul 30
1 hr 19 min
221: Weapon of mucus destruction, WMD
TWiM reveals a potential mucus-busting weapon for patients with cystic fibrosis, and bacteria in the intestinal tract that can oxidize cholesterol, leading to lower levels of the lipid in blood.
Jul 16
1 hr 8 min
220: From Mars to the vagina
TWiM reveals that methane-producing bacteria might survive beneath the surface of Mars, and identification of a cytopathogenic toxin in a bacterium associated with preterm birth.
Jul 2
43 min
219: Commensal for a healthy skin
The TWiM discusses eradicating racism in academia and STEM, and a peptide from commensal bacteria that protects skin from damage caused by MRSA
Jun 18
1 hr 2 min
218: The lengths SARS-COV-2 will go
The TWiM team explains how breathing can transmit SARS-CoV-2, and how lack of breathing leads to loss of mitochondria in a multicellular parasitic animal.
Jun 5
1 hr 2 min
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