Dave Asprey sits down with Dr. David Perlmutter to explore how brain inflammation and microglial dysfunction drive Alzheimer's, Parkinson's, and other neurodegenerative conditions — debunking the amyloid hypothesis along the way and examining emerging treatments like GLP-1 drugs, 40 hertz light therapy, and lifestyle interventions.

Jordan Harbinger: Fight-or-Flight, Two Kidnappings, and the Wallet Ruining Your Spine  : 1499

For more than a decade,&nbsp;Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee -&nbsp;has redefined what’s possible for the human mind and body. After more than a thousand episodes of&nbsp;Bulletproof Radio, he’s taking it to the next level with&nbsp;The Human Upgrade™&nbsp;- a masterclass in&nbsp;biohacking, longevity, and performance optimization.Each episode explores&nbsp;cutting-edge science, advanced technology, and proven biohacks&nbsp;to help you&nbsp;upgrade your energy, focus, metabolism, and resilience.&nbsp;You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in&nbsp;mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity,&nbsp;and more.This isn’t just self-improvement - it’s&nbsp;human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join&nbsp;The Human Upgrade™ with Dave Asprey&nbsp;- and learn how to&nbsp;live longer, think faster, and perform better.