
Are there habitable worlds that look nothing like Earth? Neil deGrasse Tyson and comic co-host Matt Kirshen discuss NASA’s Habitable Worlds Observatory and its eventual search for life beyond our solar system with astrophysicist Evgenya Shkolnik.
Nov 3
50 min

Are we losing control of AI? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O’Reilly explore AI cyberhacking breaches, supercoordation, and the game theory of the AI alignment problem with Aza Raskin, co-founder of the Center for Humane Technology and the Earth Species Project.
Oct 30
1 hr 20 min

What happens to matter when the temperature gets near zero kelvin? Neil deGrasse Tyson and Chuck Nice explore things you thought you knew about Bose-Einstein condensate, high impact collisions, and how stuff burns.
Oct 27
42 min

Could ghosts possibly be real? Neil deGrasse Tyson and Eugene Mirman explore ghost hunting techniques, spiritualism, and the non-corporeal plane of existence with Mary Roach and Joe Nickell.
Originally Aired October 30, 2011.
Oct 23
44 min

If something is possible, has the universe tried it? Are all physical possibilities inevitable? Neil deGrasse Tyson sits down with theoretical astrophysicist Janna Levin to launch “In Theory,” a new StarTalk series celebrating the weird, wacky theories of the universe and the theorists who chase them. Out on YouTube October 29, 2026!
Oct 20
40 min

Are we doing more harm than good in the pursuit of perfection? Neil deGrasse Tyson, comic co-hosts Chuck Nice and Gary O'Reilly explore looksmaxxing, peptides, body composition, and the scientization of health & beauty trends with pharmaceutical scientist & medfluencer Morgan McSweeney, aka Dr. Noc.
Oct 16
58 min

Would aliens use the same periodic table as us? Neil deGrasse Tyson and comic co-host Negin Farsad sit down with Kate Biberdorf, aka Kate the Chemist, to tackle fan questions about the chemistry of life, diamonds, how fire works, and spontaneous combustion.
Oct 13
42 min

If the multiverse exists, where does our universe end and another begin? Neil deGrasse Tyson and comic co-host Chuck Nice tackle a wide-ranging grab bag of fan questions covering bubble universes, the nature of now, fractals, Hoag's Object, and more.
Oct 6
1 hr

Why did intelligence evolve in the universe? Neil deGrasse Tyson, Chuck Nice, and Gary O’Reilly explore the nature of intelligence, information theory, consciousness, and whether AI is actually intelligent at all with David Krakauer, evolutionary biologist and president of the Santa Fe Institute.
Oct 2
1 hr 17 min

Why does string theory need ten dimensions? Neil deGrasse Tyson and comic co-host Jordan Klepper sit down with Lara Anderson, string theorist and associate professor of physics at Virginia Tech, to tackle intersecting dimensions, the nature of gravity, and a unified field theory.
Sep 29
54 min
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