Learning With Lowell
Learning With Lowell
Lowell Thompson
Cholesterol Longevity Startup Creating Custom Engineered Cyclodextrins | Dr. Matthew ‘Oki’ O’Connor -140
1 hour 16 minutes Posted Nov 8, 2022 at 11:22 pm.
Start of interview with Dr. Matthew ‘Oki’ O’Connor
Alzhiemers Gene
Data cholesterol & Alzhiemers rates
Aging therapy that affects multiple illnesses 
Team needs to execute at Cyclarity Therapeutics
Keep longevity team rowing in same direction at Cyclarity Therapeutics
His role in meetings
Oxidized Cholesterol types 
Bad types of oxidized cholesterol and the effects it has on the cell
Level changes of oxidized cholesterol with age
How body handles oxidized cholesterol
Size of issue
Custom-engineered cyclodextrins administration (Cyclarity Therapeutics therapy)
Future administration thoughts
Regulatory fun
What's left before clinical trials next year?
Prepared him to lead Cyclarity Therapeutics
Imposter Syndrome 
Dream of saving billions of lives
Scaling/Executing changes in going from concept, to clinical trials, to production
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1:16:47
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Show notes
Everything you wanted to know about longevity, cholesterol,  aging, and the brain and heart connection, but were afraid to ask.
https://youtu.be/ZvAEMWvpTJY
About Oki
“Dr. O’Connor was awarded his master’s degree in neuroscience from Northwestern Medical in 1999 and his Ph.D. in Biochemistry from Baylor College of Medicine in 2005. His postdoctoral research includes work at UC Berkeley on muscle stem cells and aging. He is the former VP of Research at SENS Research Foundation where he oversaw a broad swath of research projects spanning many aspects of rejuvenation biotechnology from which he authored many papers and patents.”
Specialties: Aging research, cyclodextrin, oxidized cholesterol, mitochondria, telomeres, IND enabling drug dev.
Links
https://www.linkedin.com/company/underdogpharmaceuticals/
https://cyclaritytx.com/
https://www.facebook.com/Underdog-Pharmaceuticals-106943334091737/
https://twitter.com/UnderdogPharma
PODCAST INFO:
The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.
LINKS
Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q
Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA
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Twitter: https://twitter.com/LWThompson5
Website: https://www.learningwithlowell.com/
Podcast email: [email protected]
Timestamps
32.30 Cyclarity Therapeutics’s therapy custom-engineered cyclodextrins and it’s effects on oxidized cholesterol