Chemist Confessions
Chemist Confessions
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#139) Which Vitamin C (Ascorbic Acid) Serum is Better? Water or Anhydrous?
35 minutes Posted May 13, 2025 at 8:00 am.
Why Is Vitamin C Such a Popular Ingredient?
Vitamin C Stability
How Fast Does Vitamin C Degrade? Study Insights
Does Vitamin C Break Down Faster in Different Temperatures?
Are Anhydrous Formulas Actually More Stable?
Breaking Down a Study: Vitamin C & Skin Tone Improvement
What Happens After 90 Days? Vitamin C Longevity
Water-Based vs. Anhydrous Vitamin C – Which Should You Buy?
How to Store Vitamin C Serums Properly
Packaging Matters – How to Choose a Serum That Lasts
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Show notes

Vitamin C, ascorbic acid, is famously known as the only rigorously tested antioxidant for age prevention. Yet this active is also notoriously known for its quirky characteristics in the classic CE Ferulic serum format. This unstable hot dog water has often generated concerns for using it long term. In this episode, the chemists discuss ascorbic acid’s stability and compare vitamin C in water-based formulas vs. anhydrous formulas to see if there’s a better format for this finicky active. 

Products Discussed this 2025 Podcast Season

*a small portion of your purchase through these links goes to feeding a chemist.
https://shopmy.us/collections/1280514

Product Shoutout:

Aquafix Hydrating Water Gel
https://chemistconfessions.com/products/aquafix-hydrating-water-gel

Enrichment Content:

Podcast Ep - Which Vitamin C Derivative is Better?
https://www.youtube.com/watch?v=b96PX4L6hsQ&t=82s

Results of our CE Ferulic Dupe Test - Pt. 1

https://chemistconfessions.com/blogs/5-skinceuticals-vitamin-c-dupes-put-to-the-test

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Resources Mentioned:

https://pubmed.ncbi.nlm.nih.gov/34986505/
https://www.sciencedirect.com/science/article/pii/S1226086X17304422 
https://www.mdpi.com/2079-9284/9/4/74 
https://www.martiderm.com/int-en/product/vitamin-c-antiox 
https://onlinelibrary.wiley.com/doi/10.1111/jocd.14837 
https://www.smithsonianmag.com/smart-news/scientists-taught-pet-parrots-to-video-call-each-other-and-the-birds-loved-it-180982041/
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1468-2494.2008.00473.x