The Uromigos
The Uromigos
The Uromigos
Broadcasting the latest developments in GU cancer Hosted by Brian Rini and Tom Powles Brian Rini MD is an Ingram Professor of Medicine (Hematology/Oncology), Vanderbilt-Ingram Cancer Center Tom Powles is the Director of Barts Cancer Centre, St Bartholomew's Hospital and Professor of Genitourinary Oncology, Queen Mary University of London
Episode 520: ESMO 2026 Preview
Silke, Brian and Tom preview the major data to be presented at ESMO 2026
Oct 12
54 min
Episode 519: What is the Appropriate Approach to Adjuvant Therapy for UTUC?
Shilpa Gupta joins us to discuss an X poll revealing equipoise about treatment approaches to resected high-risk upper tract urothelial cancer (UTUC).
Oct 5
33 min
Episode 518: PSMAddition in Clinical Practice
Rob Dreicer joins the show to discuss the FDA approval of Lutetium Lu 177 in the mHSPC space and how to contextualize the benefit/risk
Sep 28
31 min
Episode 517: Casdatifan Clinical Data in RCC and Translational Correlates
Toni Choueiri joins Brian and Tom to discuss a recent Nature paper regarding the novel HIF inhibitor, casdatifan, and biomarkers of response.
Aug 31
40 min
Episode 516: The Influence of Hypoxia on Response and Resistance in RCC
Ari Hakimi and Lyn Voung from MSKCC join Brian and Tom to discuss their recent Cancer Cell paper exploring the mechanistic impact of TKI-induced hypoxia on immune response in RCC.
Aug 17
47 min
Episode 515: PROTEUS - A Reflection on the Data and Controversies with Neha Vapiwala
Brian and Tom invite Neha Vapiwala, a Radiation Oncologist, to discuss areas of consensus and controversy from the PROTEUS trial of ADT +/- apalutamide in high-risk localized prostate cancer.
Aug 3
43 min
Episode 514: Artificial Intelligence in Cancer Drug Development
Travis Zack, CMO of Open Evidence, joins Brian and Tom to discuss the emergence of AI across the spectrum on cancer, drug development and application of data.
Jul 20
40 min
Episode 513: Trials and Tribulations of Investigator-initiated Research
Bishoy Faltas joins Brian and Tom to discuss his IIT in bladder cancer. The intended discussion of the trials turned into an insightful discussion on the challenges and learning opportunities of IITs.
Jul 13
25 min
Episode 512: ENZA-P Nature Medicine translational data
In our final episode recorded at APCCC, Louise Emmett joins us to discuss clinical results and mechanisms of PSMA upregulation by enzalutamide.
Jul 6
31 min
Episode 510: ADCs in Prostate Cancer
Tanya Dorff joins Tom and Brian to discuss her ASCO 2026 data on a novel dual targeting ADC in prostate cancer. The broader scope of ADC development in prostate cancer is discussed with a focus on cytopenia toxicity and future direcctions.
Jun 15
30 min
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