The Rao family in Maryland knew that something was different about their younger daughter, Ayoni, almost as soon as she was born. But it took them until she was five to get a diagnosis of Prader-Willi Syndrome, a rare genetic condition that causes extreme, insatiable hunger. Food needs to be locked away from many of these patients, or they might eat until their stomachs actually rupture.

The musical Sweeney Todd is about a barber who goes on a killing spree and disposes of his victims by baking them into meat pies. In an off-Broadway production, they serve you an actual meat pie before the show begins. Dr. Pamela Dalton, a researcher at the Monell Chemical Senses Center, helps us understand how food flavors and smells can affect our brains while we’re watching this kind of immersive theater.

Mandy Naglich is an award-winning home brewer who also writes and teaches about beer. Now she wants to become a Master Cicerone — basically the beer equivalent of a master sommelier.

Why do our brains go crazy for the melted cheese on Philly's iconic cheesesteak? What is it about scrapple’s crispy fried goodness? How does surface-area-to-volume ratio make the roast pork sandwich more delicious?

Is there anything better than hearing the sound of an ice cream truck approaching? Today we’re bringing you two stories of ice cream trucks, past and present. First, Sporkful managing producer Emma Morgenstern tells the tale of her great-uncles, who owned a fleet of trucks starting in the 1940s — complete with sibling rivalries, California dreaming, and the exact right speed to drive a truck to maximize profits.

Carla Hall is known for her quirky, energetic personality on TV. But in some ways she’s very different today from the woman who first appeared as a contestant on Top Chef almost two decades ago. "I didn't want to show up as my Blackness if it wasn't going to be accepted," the former co-host of The Chew says of her first foray into food media.

We’re back with our annual game show: Two Chefs And A Lie! This year our contestant is Rachel Martin, host of the NPR podcast Wild Card and an old friend of Dan’s. The game goes like this: Rachel talks with three guests.

Is the perfect burrito a feat of engineering or art? We debate burrito construction and the Los Angeles/San Francisco rivalry with Jesse Thorn (founder of Maximum Fun and host of Bullseye) and Evan Kleiman (host of KCRW's Good Food). Matt Yglesias (cofounder of Vox Media and author of the Slow Boring newsletter) compares Chipotle burritos to iPhones. And then, Dan and cookbook author/YouTuber Kenji López-Alt take some calls: A wife objects to her husband's embarrassing food hacks, and Kenji explains the science of tomato storage.

Recent studies say that somewhere between 12 and 16 percent of Americans have used GLP-1s like Ozempic, Wegovy, or Zepbound. Many people who take these drugs report that the meds have fundamentally changed their relationship to food.

“The time has come for us to change the coffee brand that we offer and we want your input!” The email came from Myiesha Gordon in the HR Department at WNYC. Like many others, Myiesha hated the office coffee.