Today, Brent has a discussion with Dr. Paul Robbins, a pioneer in the field of cellular senescence, to explore how senescent cells contribute to aging and age-related disease, and why scientists believe eliminating them could help extend healthy years of life. Robbins explains the current state of senolytic therapies, the promise of partial cellular rejuvenation, and why breakthroughs like Yamanaka factors have generated so much excitement in longevity research. The conversation also examines GLP-1 drugs, metformin, supplements, and the risks of getting ahead of the science, while offering a realistic perspective on whether humans will ever live to 150. He's a wonderful guest, hope you enjoy.