In this podcast I want to give an overall view of the field of Longevity and how much it has changed in the last 12 years. Here's a brief outline of this introductory talk, if you want to skip ahead. 00:00 -- Introduction to the Field and Innovation ( A New Shared Vision) 05:05 -- Two Key Concepts (Lifespan versus Healthspan) 10:00 -- Translational Medicine (From the lab to the clinic) 12:00 -- Longevity Medicine versus Traditional Medicine  14:25 -- The Biological Hallmarks of Aging 20:00 -- A New Vision for looking at diseases. 22:38 -- Does Aging Stop? (Michael Rose) 26:06 -- The Disciplines of Longevity ( Diet and Aging, Pharmacology, Microbiome, GMOs, Genetic Therapies) 29:40 -- The challenges of Pharmacology 31:05 -- What can we do? How do we enter the longevity lane? 38:13 -- The TRIMM trial results -- rejuvenating the thymus and epigenetic clocks