The Dr. Gabrielle Lyon Show
The Dr. Gabrielle Lyon Show
Dr. Gabrielle Lyon
The Dr. Gabrielle Lyon Show promotes a healthy world, and in order to have a healthy world, we must have transparent conversations. This show is dedicated to such conversations as the listener; your education, understanding, strength, and health are the primary focus. The goal of this show is to provide you with a framework for navigating the health and wellness space and, most importantly, being the champion of your own life. Guests include highly trustworthy professionals that bring both the art and science of wellness aspects that are both physical and mental. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician who serves the innovators, mavericks, and leaders in their fields, as well as working closely with the Special Operations Military. She is the founder of the Institute of Muscle-Centric Medicine® and serves patients worldwide.
Dr. Dariush Mozaffarian: How the Food System Got Us Sick. Can We Fix It?
What you choose to eat is the single most important decision you make every day—impacting your metabolic health, your family, the economy, and the future of our food supply.In this episode, world-renowned cardiologist and nutrition expert Dr. Dariush Mozaffarian breaks down the "Food is Medicine" movement, cuts through dietary confusion (fats vs. carbs, food label marketing, and ultra-processed ingredients), and reveals how public demand, science, and policy can repair a broken food system. If you have ever felt overwhelmed in the grocery aisle or wondered how to separate real nutrition science from industry marketing, this conversation provides a clear, practical roadmap.Thank you to our sponsors:BodyHealth: 20% off at https://bodyhealth.com with code LYON20Timeline: 20% off at http://www.timeline.com/lyonWildgrain: $40 off first box + free croissants for life at http://www.wildgrain.com/drlyon40 with code LYON40Food is Medicine by Dr. Dariush Mozaffarian: https://us.macmillan.com/books/9781250394286/foodismedicine/Chapters:00:00 - The Reality of Our Current Food System05:12 - Carbs vs. Fats: Breaking Down the Science18:40 - How to Read a Food Label Like an Expert32:15 - Ultra-Processed Foods & Why Real Food Spoils48:30 - The History of Food Policy: From the Green Revolution to Today01:05:10 - The Economics of Chronic Illness01:21:40 - The Crucible: Science, Government, and Consumer Power01:31:54 - "Food is Medicine" & Dr. Mozaffarian's Ultimate MessageExplore More from Dr. Gabrielle LyonWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patientConnect with Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyonTikTok: https://tiktok.com/@drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon/If you found this episode valuable, share it with someone who would benefit from it. Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Oct 20
1 hr 33 min
How Much Protein Do You Need? Top Scientists Still Disagree
Protein is in everything right now: coffee, chips, cookies, bars. But despite the massive marketing hype, the world’s leading scientists are still debating fundamental questions about how much protein we actually need and how the body uses it. Fresh off the Protein Summit 3.0 at Texas A&M, Dr. Gabrielle Lyon breaks down what top researchers agreed on, why treating protein as a single number is a major mistake, and how to stop falling for "high-protein" health halos in the grocery store.Find Dr. Gabrielle Lyon at:Protein is in everything right now: coffee, chips, cookies, bars. But despite the massive marketing hype, the world’s leading scientists are still debating fundamental questions about how much protein we actually need and how the body uses it. Fresh off the Protein Summit 3.0 at Texas A&M, Dr. Gabrielle Lyon breaks down what top researchers agreed on, why treating protein as a single number is a major mistake, and how to stop falling for "high-protein" health halos in the grocery store.Explore More from Dr. Gabrielle Lyon:Instagram: https://www.instagram.com/drgabriellelyon/TikTok: tiktok.com/@drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX: x.com/drgabriellelyonApply to become a patient: https://drgabriellelyon.com/new-patient-inquiry/Weekly newsletter: https://institute-for-muscle-centric-medicine.ck.pageOrder my new book: https://www.amazon.com/exec/obidos/ASIN/1668085623Chapters:00:00 - Introduction & Protein Summit02:30 - Amino Acids Beyond Muscle05:55 - Minimum vs. Optimal Protein08:13 - Lab Studies vs. Real Life10:33 - Context & Individual Needs12:04 - The Fortification Trap14:41 - The Whole Food Matrix16:18 - Research Funding & Transparency18:00 - The Future of ProteinDisclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Oct 15
21 min
Dr. Tiffany Moon: Is Anesthesia Safe? What Patients Fear vs. What Actually Happens
In this episode, board-certified anesthesiologist, researcher, and former Real Housewives of Dallas star Dr. Tiffany Moon pulls back the curtain on modern medicine, surgical pain management, and the reality of navigating elite academia. From addressing widespread public fears around clinical fentanyl use to detailing why she was branded an "embarrassment" by academic peers for appearing on reality television, Dr. Moon speaks candidly about breaking stereotypes, the gender pay gap in healthcare, and using a massive public platform to advocate for science and mentorship.What You'll Learn In This Episode:The Clinical Truth About Fentanyl: Why it is the standard of care for 90% of surgeries, and why post-op patients shouldn't fear becoming addicted.The Reality TV Fallout: How appearing on The Real Housewives led to institutional blowback—and why she’d do it again.Leveraging Fame for Science: Turning pop culture visibility into serious advocacy for mentorship, healthcare equity, and closing the gender pay gap.Shattering Stereotypes: Moving past appearances to run clinical trials, publish randomized controlled studies, and teach the next generation of physicians.Thank you to our sponsors: Cozy Earth: cozyearth.com Use code DRLYON for 20% offOur Place: fromourplace.com Use code DRLYON for 10% offBranch Basics: branchbasics.com Use code DRLYON for 15% off Premium Starter KitExplore More from Dr. Gabrielle Lyon Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patientFind Dr. Tiffany Moon at: Instagram: instagram.com/tiffanymoonmd (@tiffanymoonmd)TikTok: tiktok.com/@tiffanymoonmd (@tiffanymoonmd)YouTube: youtube.com/@TiffanyMoonMDOfficial (@TiffanyMoonMDOfficial)Website: tiffanymoonmd.comFacebook: facebook.com/tiffanymoonmd (@tiffanymoonmd)X (Twitter): x.com/TiffanyMoonMD (@TiffanyMoonMD)Connect with Dr. Gabrielle Lyon: Instagram: / drgabriellelyonTikTok: / drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: / doctorgabriellelyonChapters 00:00 – The Truth About Fentanyl in Surgery01:18 – Breaking Stereotypes in Academic Medicine12:00 – Pain Protocols, Anesthesia Safety & Clinical Trials25:00 – Reality TV, Academic Backlash & Healthcare Equity40:00 – Career Reinvention & Overcoming Physician Burnout1:00:00 – Why Preventive Medicine Is the Future1:08:39 – Longevity Medicine, GLP-1s & Muscle HealthIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Oct 13
1 hr 8 min
Hormones and Attraction: What We Think We Know vs. What the Science Says
Can you tell someone's testosterone or estrogen levels just by looking at their face? Is "jawmaxxing" actually backed by science? In this video, we dive deep into the real science of hormones, physical attraction, and evolutionary biology. We debunk popular myths around high testosterone, facial masculinity, and ovulation preferences, revealing what the research actually shows about human mate selection. Discover why facial structure isn't a hormone panel, how estrogen impacts skin and collagen as women age, and why physical strength accounts for 70% of perceived bodily attractiveness. If you want to understand how hormones shape our development—and why muscle is the single most modifiable signal of health and longevity—this episode is for you.Find Dr. Gabrielle Lyon at:- Instagram: https://www.instagram.com/drgabriellelyon/- TikTok: tiktok.com/@drgabriellelyon- Facebook: facebook.com/doctorgabriellelyon- YouTube: youtube.com/@DrGabrielleLyon- X: x.com/drgabriellelyon- Apply to become a patient: https://drgabriellelyon.com/new-patient-inquiry/- Weekly newsletter: https://institute-for-muscle-centric-medicine.ck.page- Order my new book: https://www.amazon.com/exec/obidos/ASIN/1668085623Chapters:00:00 What role do hormones play in the traits we find attractive? 00:46 High vs. low testosterone: does it change who we pick? 01:44 The ovulation story: do women seek out masculine men? 03:19 Two questions: can you see hormones, and what's modifiable? 04:12 What testosterone and estrogen build during development 05:23 Does winning raise testosterone? What a masculine face tells you 06:26 Selection, training and genes: why muscle isn't just testosterone 07:54 Are women attracted to testosterone? What the longitudinal studies show 09:29 Face vs. strength: what predicts mating success 10:08 The 70% finding: strength and bodily attractiveness 11:44 Why strength is a hard-to-fake health signal 13:41 Can you see estrogen? Facial ratings and why more isn't better 14:41 Culture moves beauty standards, and estrogen shows up in skin 16:08 Estrogen therapy and skin: what it can and can't do 16:36 Can you see hormones? Muscle is the system you can see and changeDisclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Oct 8
17 min
Dr. JJ Thomas: Pain Is an Alarm. Why Your Injury Keeps Coming Back and How To Fix It
When you have musculoskeletal pain, the natural instinct is to try and treat it directly. But the cause of that pain often starts somewhere else in the body.I learned that from this week's guest, Dr. JJ Thomas, who is my physical therapist and good friend. She was my patient first, and now we are each other's patients. She has practiced physical therapy for more than 25 years and has worked with the Philadelphia 76ers, the Philadelphia Eagles, and athletes from the UFC and US Olympic programs.What you'll learn in this episode:Why a chronic tendon injury can come right back, even after eccentric loading or PRPWhether a frozen shoulder in menopause is a hormone problem, and one of the first movements Dr. Thomas checksWhy she works lying on her stomach, and the 10-minute band routine she wrote for an eight-hour desk dayWhy sitting up taller won't fix your posture, and what poor posture tells her about your bodyWhy she gives patients shoulder blade exercises for their pelvic floorHow much a standard squat does for your posterior chain, and the position she wants you in more oftenWhy she believes “overuse” injuries are often underuse injuries, and how that changes the way she treats shin splintsWhy needling a clinician's quad and adductors normalized his neck rotationWhat her blood work showed after years of hard training, and the nutrition change she calls her “game changer”Thank you to our sponsors:• Manukora - Get 31% off at https://www.manukora.com/drlyon• Timeline - up to 20% off when you subscribe and save at https://www.timeline.com/lyon• Bon Charge - Use code DRLYON for 15% off at https://www.boncharge.comExplore More from Dr. Gabrielle LyonWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patie...Find Dr. JJ Thomas at:• YouTube: https://www.youtube.com/@drjjthomas• Website: https://primalphysicaltherapy.com/• Instagram: https://www.instagram.com/drjjphysicaltherapist/Connect with Dr. Gabrielle Lyon:• Instagram: https://www.instagram.com/drgabriellelyon/• TikTok: https://www.tiktok.com/@drgabriellelyon • Facebook: http://facebook.com/doctorgabriellelyon• X: http://x.com/drgabriellelyon• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/• Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageChapters00:00 – Posture Myths & Why Sitting Up Straight Fails02:18 – Treating Root Causes vs. Bandaging Pain06:48 – The Hazards of Sitting & Reframing Movement as Health13:39 – The 7 Primal Movement Patterns Every Body Needs25:28 – Scapular Stability, Pelvic Health, and Primal Movements39:12 – Fixing Glute Amnesia & Activating the Posterior Chain51:57 – Why "Overuse" Injuries Are Really Underuse Problems58:34 – Dry Needling & System-Based Movement Resets1:13:53 – Dialing in Hormones, Protein, and Metabolic HealthIf you found this episode valuable, share it with someone who would benefit from it.Disclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Oct 6
1 hr 30 min
Is It Too Late to Build Muscle in Menopause? No. Here's What the Studies Show
Will I get too bulky?" No. "Is it too late?" Also no. Here's the context: during the menopause transition, women lose lean mass, gain fat, and their muscle becomes harder to build — the same workout and the same protein meal produce less than they did at 30. For years the only conversation has been hormone therapy, yes or no, as if that were the fix. In Part 2 of her menopause series, Dr. Gabrielle Lyon looks at what the evidence actually says builds muscle back.In this episode:-Postmenopausal women can build muscle and strength at any age (Frontiers in Endocrinology)- Up to 8 lbs of skeletal muscle in 12 weeks (J Nutr Health Aging RCT)- Anabolic resistance: why the same workout and the same meal produce less after menopause- "I was wrong": hormone therapy vs. lifting, and the conversations with Dr. Donald Layman- HRT alone and lean mass: a 0.06 kg difference across 12 trials- Estradiol plus training: bigger quad and fat-free mass gains, maintained at 12 months- Lift first — the practical translation while the HRT evidence evolves- Why protein matters more after menopause, and why 60 g spread thin isn't enough- The RDA (0.8 g/kg) isn't enough to protect bone; ESCEO's 1–1.2 g/kg floor- Doubling protein to 1.6 g/kg: more fat lost, more lean mass kept- The 6-step Forever Strong menopause protocolSponsorDavid Protein — 28 g of protein, 150 calories, zero sugar → davidprotein.com/drlyon, subscribe to save 10% on every orderFind Dr. Gabrielle Lyon at:- Instagram: https://www.instagram.com/drgabriellelyon/- TikTok: tiktok.com/@drgabriellelyon- Facebook: facebook.com/doctorgabriellelyon- X: x.com/drgabriellelyon- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/- Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageChapters:00:00 Will I get too bulky? Is it too late? Both answers are no01:09 Postmenopausal women gained up to 8 lbs of muscle in 12 weeks02:24 Anabolic resistance: more volume, more intensity, more protein03:34 Hormone therapy or lifting? "I was wrong"05:16 HRT alone and lean mass: 0.06 kg across 12 trials06:16 Estradiol amplifies training — it doesn't replace it07:22 Lift first: what to do while the evidence evolves10:21 Why protein matters more after menopause (and why 60 g isn't enough)11:16 The RDA won't protect your bones: the 1–1.2 g/kg floor12:16 Doubling protein: more fat lost, more lean mass kept13:22 The Forever Strong protocol, step 1: train 2–3 days a week14:15 Steps 2–3: 30–50 g protein at first and last meal, impact and loading15:13 Steps 4–6: hormone therapy with training, body composition, blood work16:07 You're not alone: the Menopause ChallengeDisclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
Oct 1
17 min
How to Prepare Your Body for Surgery: Protein, Prehab and the 5 Days That Change Your Recovery | Dr. Rebecca Knackstedt
Most patients are told one thing before surgery: stop all supplements. Duke surgeon Dr. Rebecca Knackstedt says that blanket advice can do harm, and that what you do in the days before surgery changes how you heal.Dr. Knackstedt is a plastic and reconstructive microsurgeon on faculty at Duke, an MD-PhD researcher and a certified functional medicine provider whose research focuses on surgical prehabilitation: preparing the body, mind, and home before surgery, the way we already do with rehab.In today’s episode, we discuss:• What prehab looks like for any operation• The labs she checks• Which supplements to keep and which to stop (omega-3s do not increase bleeding)• Hormones after breast cancer• Why mammograms still beat thermography• What chemo does to metabolism• The questions to ask your oncologist before a treatment decision• How much protein to eat (no standard exists, and the average woman gets 60 to 70 grams a day, well short of the 100-gram floor)• Why surgery is catabolic and muscle is your reserve• Carbohydrate loading before the fasting cutoff and why it can reduce pain• The five-day window that lowered complications and even mortality in head and neck cancer patients• Why early walking replaced routine bed restConnect with Dr. KnackstedtInstagram → https://www.instagram.com/surgical_recovery/Website → https://www.clararecovery.com/Sponsors• Perfect Amino by BodyHealth, https://bit.ly/4wZgg6N, code LYON20 for 20% off your first order• Timeline Mitopure → https://bit.ly/4x18cm5, for an extra 20% off• Lola Blankets → lolablankets.com (http://lolablankets.com/), code: DRLYON for 40% off select blankets (limited time)Find Dr. Gabrielle Lyon at:• Instagram: https://www.instagram.com/drgabriellelyon/• TikTok: tiktok.com/@drgabriellelyon• Facebook: http://facebook.com/doctorgabriellelyon• X: http://x.com/drgabriellelyon• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/• Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageChapters:00:00 Prehab saves lives and money. So why isn't it standard of care?01:05 Meet Dr. Rebecca Knackstedt: Duke microsurgeon and functional medicine provider05:35 The patient who changed everything, and why good surgery isn't enough08:34 What prehab is, and the exercises to do before any surgery12:14 Hormones after breast cancer, rising rates in young women, and real risk factors18:42 Chemo, metabolic syndrome and why body composition matters23:13 The end of bed rest, and the labs that matter before surgery27:04 Mammograms vs. thermography, and absolute vs. relative risk34:12 Protein before surgery: 2 g/kg, track 3 days, never under 100 g38:43 Supplements to take, and why "stop all supplements" is wrong44:40 Preparing the mind: anxiety, sleep, anesthesia depression, expectations51:21 Red light, saunas, hyperbaric oxygen, wound vacs, scars and pain control1:04:59 Surgery is catabolic: muscle as your glucose reserve1:07:34 Carb loading, the 5-day window, probiotics and the surgery go-bag1:14:15 Why prehab isn't standard of care yet, and why she's hopefulDisclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
Sep 29
1 hr 17 min
Menopause Is a Muscle Problem, Not Just a Hormone Problem
Menopause is changing your body, but the part nobody talks about isn't hot flashes. It's muscle. Women lose lean mass fastest in perimenopause, the loss probably starts closer to 35, and no pill, patch or injection fixes it.In this solocast, Dr. Gabrielle Lyon explains what estrogen, testosterone and FSH actually do to your metabolism, why a 50-year-old body can still build muscle, and the training and protein protocol to start now.Join the Menopause Challenge →https://drgabriellelyon.com/menopause-challenge/[Use Code 25OFF through Sept 27]Thank you to our sponsors:- Rula, therapy covered by insurance → rula.com/drlyonFind Dr. Gabrielle Lyon at:- Instagram: https://www.instagram.com/drgabriellelyon/- TikTok: @drgabriellelyon- Facebook: facebook.com/doctorgabriellelyon- YouTube: youtube.com/@DrGabrielleLyon- X (Twitter): x.com/drgabriellelyon- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page- Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623Chapters:00:00 Menopause is changing your body — but it doesn't have to change your life00:59 The suitcase story: today is about muscle, not hot flashes01:47 Hormone therapy, yes or no? Why that's the wrong first question03:36 What menopause is, when it arrives, and 40% of your life after it04:37 When lean mass really starts to fall — and why testing misses it06:46 Testosterone vs. estrogen: no two women go through it the same way08:40 Anabolic resistance: why the muscle-building switch gets sticky10:31 Estrogen, joints and injury risk (Dr. Jocelyn Wittstein)13:27 Less muscle, nowhere to put carbs: the lean prediabetic patient14:19 Falls, fractures, heart disease, and muscle as an early bone signal16:14 Visceral fat, energy expenditure, fat oxidation and FSH18:02 Test your blood — and pull the levers you control19:00 The starting protocol: 2–3 days a week and the movements to keep20:30 Menopause changes your body, not your life — the Menopause ChallengeMentioned- Dr. Jocelyn Wittstein on estrogen, joints and injury risk → https://youtu.be/ILyzNTjZTGI- Juliet & Dr. Kelly Starrett on floor sitting and mobility → https://youtu.be/QOjzh-711Q0- SWAN (Study of Women's Health Across the Nation)- The Lancet Diabetes & Endocrinology review on lean mass and chronic disease- ESCEO guidance on muscle and boneDisclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Sep 24
22 min
ED Predicts Heart Attacks Better Than Chest Pain: The 2 Tests to Ask For | Dr. Tobias Kohler
Your testosterone number matters at every age, but most men never learn what theirs should be. Mayo Clinic urologist Dr. Tobias Kohler explains why ~500 is the target, why 1,000 is already running hot, what 2,000+ does to the heart, and why a randomized trial found lifting without steroids beat steroids without lifting. Plus: the blood test that catches heart risk your cholesterol panel misses.Dr. Kohler returns for his second appearance (his first, on erections, testosterone and muscle mass, is one of the most-watched episodes in the show's history). This time: why men's longevity is roughly 50 years behind women's; the Princeton IV consensus he co-chaired, which treats ED as one of the strongest predictors of a future heart attack and points young men toward a coronary calcium scan; the 0–12 ceramide blood test that changes with your behavior; how to get a testosterone baseline that actually means something; what redlining to 2,000–3,000 does to the heart, the set point and the skin; Peyronie's disease, Viagra vs. Cialis, the pills-to-implant ladder, sexual rehab after prostate surgery, and a patient who got stronger with zero testosterone.About Dr. Tobias KohlerTobias S. Kohler, MD, MPH, is Professor of Urology at Mayo Clinic, a fellowship-trained andrologist with 25+ years of clinical and surgical experience and 250+ peer-reviewed publications. He co-chaired the Princeton IV Consensus Guidelines on ED and cardiovascular disease, co-founded the EROS penile implant registry, and co-edited Contemporary Treatment of Erectile Dysfunction (2nd ed.).🙌 Thank you to our sponsors:Cozy Earth - Get 20% off at https://bit.ly/3RLZNEvEgg Life - https://bit.ly/4yxBs5lLadder - https://bit.ly/4ggxfLK📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:YouTube: https://bit.ly/4boCFC3Spotify: https://bit.ly/4cWTbLG📱 Connect with Dr. Gabrielle Lyon:Instagram: https://bit.ly/4uk9adcTikTok: https://bit.ly/3OFK3kJX.com: https://bit.ly/4l3YlaXFacebook: https://bit.ly/3MBrJsoLinkedIn: https://bit.ly/3N1nrdLWebsite: https://bit.ly/3NdV2kTBooks: https://bit.ly/4r6ugZKNewsletter: https://bit.ly/402QCAj⏰Chapters00:00 Men are dying earlier than women the penis is the check-engine light03:26 Boys stop seeing doctors for 20 years the case for an Office of Men's Health10:57 Princeton IV: ED predicts heart attacks, calcium scans, and Cialis12:44 The ceramide blood test your cholesterol panel can't replace20:37 Cardiac risk calculators, statins, and what your LDL should be25:38 GLP-1s, fertility, and "what's the risk of doing nothing?"29:05 Testosterone: the ~500 target, why 1,000 runs hot, what 2,000+ does to the heart31:44 Check your testosterone at 25 and why steroids won't make you a pro36:57 Tolerance and the new set point redlined men can't escape38:13 The 1980s trial: lifting without steroids beat steroids without lifting42:06 Steroid cocktails, arrhythmias, irreversible side effects, and the sarcopenia trade-off53:04 Peyronie's disease and Viagra vs. Cialis57:32 Penile implants: the knee-replacement analogy and the pills-to-surgery ladder1:02:27 Sexual rehab after prostatectomy and the questions to ask before cancer treatment1:07:55 Closing: be proactive and the patient who got stronger with zero testosteroneDisclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.
Sep 22
1 hr 11 min
The Truth About Testosterone in Women
You say "steroids" and picture a baseball scandal, a jacked guy, a bad spray tan. But cortisol is a steroid. Estrogen is a steroid. The cream you put on poison ivy is a steroid. The word covering all of them is also covering testosterone therapy for women, and that collision is quietly costing women muscle and bone they don't have to lose.In this solo episode, prompted by a magazine interview on steroid use in women, Dr. Gabrielle Lyon breaks down what these molecules actually are, what they do inside a cell, and why the line between medicine and misuse has nothing to do with the word "steroid."Study and References:The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in Normal Men (Bhasin et al., NEJM 1996) - https://pubmed.ncbi.nlm.nih.gov/8637535/Testosterone Enhances Estradiol's Effects on Postmenopausal Bone Density and Sexuality (Davis et al., 1995) - https://pubmed.ncbi.nlm.nih.gov/7616872/Global Consensus Position Statement on the Use of Testosterone Therapy for Women (2019) - https://pubmed.ncbi.nlm.nih.gov/31498...ISSWSH Clinical Practice Guideline for the Use of Systemic Testosterone for HSDD in Women (2021) - https://pubmed.ncbi.nlm.nih.gov/33814...The Global Epidemiology of Anabolic-Androgenic Steroid Use: A Meta-Analysis (Sagoe et al., 2014) - https://pubmed.ncbi.nlm.nih.gov/24582...What Is the Prevalence of Anabolic-Androgenic Steroid Use Among Women? A Systematic Review (Piatkowski et al., Addiction, 2024) - https://onlinelibrary.wiley.com/doi/1... "The Compounds for Females Are Really Commonly Faked!": Women's Challenges in Anabolic Steroid Acquisition (Piatkowski et al., Drug and Alcohol Review, 2024) - https://onlinelibrary.wiley.com/doi/1...Explore More from Dr. Gabrielle Lyon:Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team https://drgabriellelyon.com/new-patie...📱 Connect with Dr. Gabrielle Lyon:Instagram: https://bit.ly/4uk9adcTikTok: https://bit.ly/3OFK3kJX.com: https://bit.ly/4l3YlaXFacebook: https://bit.ly/3MBrJsoLinkedIn: https://bit.ly/3N1nrdLWebsite: https://bit.ly/3NdV2kTBooks: https://bit.ly/4r6ugZKNewsletter: https://bit.ly/402QCAj📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:YouTube: https://bit.ly/4boCFC3Spotify: https://bit.ly/4cWTbLG⏰ Chapters:00:00 - Beginning01:25 - Introduction: The Sister Who Says "Oh My Gosh, You're Taking Steroids" Why Medicine Needs a Shared Vocabulary03:43 - What a Steroid Actually Is: Four Rings of Carbon04:49 - Anabolic vs. Androgenic: Same Receptor, Different Effects06:16 - A Brief History: From Wasting Disease to the Weight Room08:59 - Restoring vs. Exceeding: Why the Range Is the Whole Game11:38 - The Davis Trial: Testosterone, Bone Density, and Lean Mass13:38 - Oral Compounds, the Liver, and Why Conversion Matters14:20 - What Gets Sold Isn't What's Labeled: The Australian Drug-Checking Data15:31 - The 1.6% vs. 4% Myth: Reading the Prevalence Data Correctly18:33 - Why GLP-1s Are Pushing Women Toward Androgens20:26 - Permanent Effects: Voice Changes and What the Literature Shows21:33 - The Four Questions to Ask Before Any Androgen Conversation24:25 - Closing: Entering the Sarcopenia Era‼️ Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.
Sep 17
25 min
Load more