During this episode of SurgOnc Today, Richard White, MD, Chair of the SSO Melanoma Disease Site Work Group and Giorgos Karakousis, MD, explore the science behind gene expression profiling and its role in patients with early stage melanoma.

In this episode Carmen Solorzano, MD, Chair of the SSO Endocrine Disease Site Work Group, Electron Kebebew, MD, and Geoffrey Young, MD, PhD, discuss two practice changing studies regarding the management of Medullary and Anaplastic Thyroid Cancer.

Recent trials in sarcoma sought to determine the impact of neoadjuvant therapies and histologic/genomically specific treatments. Valerie Grignol, MD, Gabriel R. Tinoco Suarez, MD, and Alessandro Gronchi, MD, FSSO discuss the following recent trials: The EORTC-62902:STRASS trial, the NAVIGATOR study and lastly the INVICTUS study evaluated the impact of further line therapy ripretinib, a switch-control tyrosine kinase inhibitor, on progression-free survival in advanced gastrointestinal stromal tumors.

In this episode of SurgOnc Today™, Evan Glazer, MD, PhD, FACS, FSSO, Vice Chair of the SSO Gastrointestinal Disease Site Workgroup, is joined by Julie Hallet MD, MSc, FRCSC, Natalie Coburn MD, MPH and Jesse Zuckerman, MDCM, all from the University of Toronto. Focusing on 2020 Practice Changing Studies in Gastrointestinal Surgical Oncology, they review the Declining Use of Red Blood Cell Transfusions for Gastrointestinal Cancer Surgery: A Population-Based Analysis. Ann Surg Oncol 28, 29–38 (2021).

In this episode, Peritoneal Surface Malignancy Disease Site Workgroup Member, Beth Helmink, MD, PhD, from Washington University in St. Louis, reviews recent data regarding the evolving role of HIPEC in Ovarian Cancer.  Joining her for this discussion are two renowned gynecologic oncologists specializing the treatment of ovarian cancer, Willemien van Driel, MD, Netherlands Cancer Institute, and Ernst Lengyel, MD, PhD, University of Chicago.

In this episode, Karyn Stitzenberg, MD, MPH, Vice Chair of the SSO Colorectal Disease Site Work Group is joined by Patrick S. Sullivan, MD, FACS, FASCRS, Associate Professor of Surgery and Chief Quality Officer, Division of Colorectal Surgery at the Winship Cancer Institute of Emory University in Atlanta, Georgia. They review practice changing studies in colorectal surgical oncology from 2020.

In this episode, Melissa Hogg, MD from Northshore University Health System, chair of the Hepato-Pancreato-Biliary Disease Site Workgroup, is joined by Jashodeep Datta, MD, from the University of Miami School of Medicine in Miami, FL and Dr. Carrie Luu, MD, from Saint Louis University Hospital in St. Louis, MO.  They review practice changing studies in Hepato-Pancreato-Biliary Surgical Oncology from 2020. They discuss the SWOG S1505 clinical trial manuscript and the Know Your Tumor Registry publication.

Ko Un “Clara” Park, MD, FACS, and member of the SSO Breast DSWG reviews wire-free alternatives for localization of non-palpable breast lesions for surgery. Michael Alvarado, MD, MS, discusses the use of radioactive seed. Susan Hoover, MD, reviews other ‘seed-like’ localizers such as Savi Scout, Magseed, and the Faxitron localizer. Lee G. Wilke, MD, discusses an innovative intraoperative navigation platform for tumor identification, a Smart Clip technology which can be inserted at time of the biops

Anthony Yang, MD, MS, Chair of the SSO Endocrine Disease Site Work Group is joined by fellow Workgroup Members, Mark Cohen, MD, FSSO and Cord Sturgeon, MD, MS, along with Samuel Hyde, CGC. This episode is the first of a two-part series.  The panel discusses the incidence, prevalence, and epidemiology of primary hyperparathyroidism (PHPT).  They also review inherited syndromes associated with PHPT as well as when to send patients/families to genetic counseling and how to diagnose those syndromes.

Anthony Yang, MD, MS, Chair of the SSO Endocrine Disease Site Work Group is joined by fellow Workgroup Members, Mark Cohen, MD, FSSO and Cord Sturgeon, MD, MS, along with Samuel Hyde, CGC. This podcast is the second of a two-part series.  Whereas the first episode discussed an overview of primary hyperparathyroidism (PHPT), this episode focuses on the surgical management of hereditary forms of PHPT, specifically multiple endocrine neoplasia syndromes types 1 & 2.