In this presentation we will talk about the first experimental station to be open for users at Sirius, the 4th generation Synchrotron Light Source in Campinas, Brazil. Sirius is affiliated with CNPEM, the Brazilian Center for Research in Energy and Materials, maintained by the Brazilian Ministry of Science Technology and Innovation. The Manacá beamline is a micro focus station dedicated to macro molecular crystallography. We are currently open for proposals, and continually working on further developments in the area of serial crystallography and new methods for structural biology.