Recorded onsite at SLAS2023 in San Diego, California, podcast Editor Rob Howes speaks with Davide Gianni, Ph.D. (AstraZeneca) to learn more about Gianni's protocol paper, "A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets," published in Volume 28, Issue 2 of SLAS Discovery. Here Davide describes the development of a 384-well plate-based multi-parametric imaging assay designed to capture ex vivo primary islet proliferation, a known...
Sep 13, 2023
8 min
Welcome to the SLAS Discovery Author Insights podcast! Today we are joined by Antonia Turberville and Geoffrey A. Holdgate to discuss their recent perspective article titled "A perspective on the discovery of enzyme activators". This article sheds light on the largely under-explored area of enzyme activation in drug discovery. Despite the successful application of enzyme activators in various therapeutic interventions, the field remains under-represented and poorly exploited. Antonia and Geo...
Mar 29, 2023
9 min
Traditionally, SLAS Discovery has focused on publishing original research papers and reviews. With the introduction of this latest special issue, the journal is expanding its scope to include protocol articles. These articles are designed to provide a detailed, step-by-step guide to a particular experimental technique or methodology, enabling other researchers to replicate the work and build upon it. In this episode, we spoke with one of the special issue Guest Editors, Adam Zweifach, Ph.D. (...
Feb 22, 2023
12 min
Tune in to this special episode of SLAS Discovery Author Insights, recorded onsite at SLAS Europe in Dublin, Ireland. Join podcast Editor Rob Howes as he chats with Jonathan Wingfield, Ph.D. (AstraZeneca UK) about the return to in-person meetings, his experience working as a global researcher, and his latest research projects and collaborations. Learn about his journey from a start in microbiology and academia, and his path leading to a role as Principal Scientist at AstraZeneca with a ...
Sep 21, 2022
12 min
Tune in to this special episode of SLAS Discovery Author Insights, which was recorded onsite at SLAS Europe in Dublin, Ireland. Join podcast Editor Rob Howes as he chats with Timothy Spicer, Ph.D. (Scripps Florida) about his myriad roles within SLAS as President, Associate Editor, volunteer, and even author. Hear more about his journey to becoming SLAS President, his significant contributions to SLAS Discovery, as well as his latest research and collaborations. For more information abou...
Jul 20, 2022
15 min
Volume 27 Issue 3, April 2022 Behind April's Special Issue: Join podcast host Rob Howes (Rosalind Franklin Laboratory) as he invites Guest Editor Glauco Souza (Greiner Bio-One) to discuss the special issue covering 3D Cell Culture. They cover the timeliness of this issue as the world recovers from a global pandemic that revealed the need for more realistic and predictive in vitro models for biology, as well as the demand for more efficient technologies as researchers catch up on their benchw...
Apr 27, 2022
15 min
SLAS Discovery Editor-in-Chief Bob Campbell (Twentyeight-seven Therapeutics) welcomes Sarine Markossian, Ph.D. (National Center for Advancing Translational Sciences (NCATS)) and G. Sitta Sittampalam, Ph.D. (National Center for Advancing Translational Sciences (NCATS)) to discuss the research featured in the latest Special Issue of SLAS Discovery. Titled “Assay Guidance Manual for Drug Discovery: Robust or Go Bust”, this issue showcases the incorporation of best practices in early research sta...
Dec 15, 2021
19 min
Join Jill Hronek, SLAS Director of Marketing and Communications, and Ally Jump, SLAS Publishing Manager, as they speak with SLAS Discovery and SLAS Technology’s respective Editors-in-Chief, Robert M. Campbell, Ph.D., (Twentyeight-Seven Therapeutics, Boston, MA USA) and Edward Kai-Hua Chow, Ph.D., (National University of Singapore, Singapore) about SLAS’s new Open Access model for the Society’s two peer-reviewed journals. Beginning January 1, 2022 both SLAS Discovery and SLAS Techn...
Oct 27, 2021
13 min
Podcast Editor Rob Howes chats with Geoffrey A. Holdgate, Ph.D. (AstraZeneca) and Christian Bergsdorf, Ph.D. (Novartis), Guest Editors of the Special Collection: Applications of Biophysics in Early Drug Discovery. This special collection explores the use of biophysical methods in the identification and characterization of molecules in early drug discovery. The biophysical methods toolbox be applied to complement traditional biochemical approaches in research including early assay developmen...
Sep 22, 2021
14 min
Volume 26 Issue 7, August 2021 Podcast Editor Rob Howes chats with Jayme L. Dahlin, MD, Ph.D. (National Center for Advancing Translational Sciences (NCATS)), Guest Editor of the Special Collection: Approaches for Prioritizing High-Quality Chemical Matter in Chemical Probe and Drug Discovery. This Special Issue of SLAS Discovery discusses the art and science of identifying high-quality chemical matter in screening, to avoid diverting lab resources and flawed findings. For a more in-d...
Aug 18, 2021
19 min
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