This article "NSD2 targeting reverses plasticity and drug resistance in prostate cancer" is published in Nature.Author: Jia J. Li Journal: Nature Year: 2025 Podcast type: ShortThe authors are:Jia J. LiAlessandro VasciaveoDimitris KaragiannisZhen SunKristjan H. GretarssonXiao ChenOuathek OuerfelliFabio SocciarelliZiv FrankensteinHanyang DongMin ZouWei YuanGuangli YangGabriel M. AizenmanTania PannelliniXinjing XuHimisha BeltranYu ChenKevin GardnerBrian D. RobinsonJohann de BonoOr GozaniCory Abate-ShenMark A. RubinMassimo LodaCharles L. SawyersAndrea CalifanoChao LuMichael M. ShenAffiliations:Jia J. Li, Cory Abate-Shen, Andrea Califano, Michael M. Shen, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Jia J. Li, Alessandro Vasciaveo, Cory Abate-Shen, Andrea Califano, Michael M. Shen, Department of Systems Biology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Jia J. Li, Dimitris Karagiannis, Kristjan H. Gretarsson, Xiao Chen, Chao Lu, Michael M. Shen, Department of Genetics and Development, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Jia J. Li, Cory Abate-Shen, Michael M. Shen, Department of Urology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Jia J. Li, Alessandro Vasciaveo, Dimitris Karagiannis, Kristjan H. Gretarsson, Xiao Chen, Ziv Frankenstein, Min Zou, Cory Abate-Shen, Andrea Califano, Chao Lu, Michael M. Shen, Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Alessandro Vasciaveo, Gabriel M. Aizenman, Center for Data Science and Artificial Intelligence, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA Alessandro Vasciaveo, Gabriel M. Aizenman, Center for Therapeutics Discovery, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA Alessandro Vasciaveo, Gabriel M. Aizenman, Cancer Genome and Epigenetics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA Zhen Sun, Yu Chen, Charles L. Sawyers, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA Ouathek Ouerfelli, Guangli Yang, Organic Synthesis Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA Fabio Socciarelli, Tania Pannellini, Brian D. Robinson, Massimo Loda, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA Ziv Frankenstein, Kevin Gardner, Cory Abate-Shen, Department of Pathology and Cell Biology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Hanyang Dong, Or Gozani, Department of Biology, Stanford University, Stanford, CA, USA Min Zou, Cory Abate-Shen, Department of Molecular Pharmacology and Therapeutics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Wei Yuan, Johann de Bono, Division of Clinical Studies, The Institute of Cancer Research, London, UK Himisha Beltran, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA Yu Chen, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA Mark A. Rubin, Department of Biomedical Research, Bern Center for Precision Medicine, University of Bern, Bern, Switzerland Massimo Loda, Nuffield Department of Surgical Sciences, Lincoln College, University of Oxford, Oxford, UK Charles L. Sawyers, Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA Andrea Califano, Department of Biomedical Informatics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA Andrea Califano, Department of Biochemistry and Molecular Biophysics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA

This article "Discovery of Late Intermediates in Methylenomycin Biosynthesis Active against Drug-Resistant Gram-Positive Bacterial Pathogens" is published in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.Author: Christophe Corre Journal: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Year: 2025 Podcast type: ShortThe authors are:Christophe CorreGideon A. IdowuLijiang SongMelanie E. WhiteheadLona M. AlkhalafGregory L. ChallisAffiliations:Christophe Corre, Gideon A. Idowu, Lijiang Song, Melanie E. Whitehead, Lona M. Alkhalaf, Gregory L. Challis, Department of Chemistry, University of Warwick, Coventry CV4 7AL, U.K. Christophe Corre, School of Life Sciences, University of Warwick, Coventry CV4 7AL, U.K. Gregory L. Challis, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute and ARC Centre of Excellence for Innovations in Peptide and Protein Science, Monash University, Clayton, Victoria 3800, Australia

This article "Mass-spectrometry-based draft of the human proteome" is published in Nature.Author: Mathias Wilhelm Journal: Nature Year: 2014 Podcast type: ShortThe authors are:Mathias WilhelmJudith SchleglHannes HahneAmin Moghaddas GholamiMarcus LieberenzMikhail M. SavitskiEmanuel ZieglerLars ButzmannSiegfried GessulatHarald MarxToby MathiesonSimone LemeerKarsten SchnatbaumUlf ReimerHolger WenschuhMartin MollenhauerJulia Slotta-HuspeninaJoos-Hendrik BoeseMarcus BantscheffAnja GerstmairFranz FaerberBernhard KusterAffiliations:Mathias Wilhelm, Hannes Hahne, Amin Moghaddas Gholami, Harald Marx, Simone Lemeer, Bernhard Kuster, Chair of Proteomics and Bioanalytics (Technical University of Munich) Mathias Wilhelm, Judith Schlegl, Marcus Lieberenz, Emanuel Ziegler, Lars Butzmann, Siegfried Gessulat, Joos-Hendrik Boese, Anja Gerstmair, Franz Faerber.

The article "Multi-agent AI enables evidence-based cell annotation in single-cell transcriptomics" is from a preprint server and was posted on bioRxiv.Author: Gautam Ahuja Journal: bioRxivYear: 2025 Podcast type: ShortThe authors are:Gautam AhujaAlex AntillYi SuGiovanni Marco Dall'OlioSukhitha BasnayakeGöran KarlssonParashar DhapolaAffiliations:Gautam Ahuja, Yi Su, Sukhitha Basnayake, Parashar Dhapola, Nygen Analytics AB, Medicon Village, Lund, Sweden Alex Antill, Göran Karlsson, Stem Cell and Leukemia Lab, Lund University, Sweden Giovanni Marco Dall'Olio, GMD Bioinformatics, UK

pdf1182This article "Antimicrobial resistance and comparative genome analysis of high-risk Escherichia coli clones isolated from Egyptian children with diarrhoea" is from a preprint server and was posted on bioRxiv.Author: Radwa Abdelwahab Journal: bioRxivYear: 2025 Podcast type: ShortThe authors are:Radwa AbdelwahabMunirah M. AlhammadiMuhammad YasirEhsan A. HassanEntsar H. AhmedNagla H. Abu-FaddanEnas A. DaefStephen J. W. BusbyDouglas F. BrowningAffiliations:Radwa Abdelwahab, Muhammad Yasir, Stephen J. W. Busby, Institute of Microbiology and Infection. School of Biosciences, University of Birmingham. Birmingham. B15 2TT, UK Radwa Abdelwahab, Ehsan A. Hassan, Entsar H. Ahmed, Nagla H. Abu-Faddan, Enas A. Daef, Faculty of Medicine, Assiut University, Assiut 71515, Egypt Munirah M. Alhammadi, Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia Douglas F. Browning, Quadram Institute Bioscience, Norwich Research Park, Norwich, NR4 7UQ, UK Douglas F. Browning, College of Health and Life Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET, UK

This article "A tripartite alliance for dietary fat absorption" is published in Science.Author: Ralph Burkhardt Journal: Science Year: 2025 Podcast type: ShortThe authors are:Ralph BurkhardtJosef EckerAffiliations:Ralph Burkhardt, Josef Ecker, University Hospital Regensburg, Regensburg, Germany

This article "Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation" is published in Cell Reports.Author: Chiara H. Moretti Journal: Cell Reports Year: 2025 Podcast type: ShortThe authors are:Chiara H. MorettiEstelle GrassetJiaying ZhuGaohua YangLouise E. OlofssonMuhammad Tanweer KhanPer-Olof BerghJee-Hwan OhAnnika LundqvistTom van GilsManuela KrämerLisa M. OlssonPiyush PatelMatthias MittereggerDaysi Espinola MongesChinmay DwibediKimberly A. KrautkramerNienke KoopmanMarcus HenricssonAndrew J. MacphersonThue SchwartzGianfranco GromponeJan-Peter van PijkerenValentina TremaroliStefan RoosMagnus SimrénFredrik BäckhedAffiliations:Chiara H. Moretti, Estelle Grasset, Jiaying Zhu, Gaohua Yang, Louise E. Olofsson, Muhammad Tanweer Khan, Per-Olof Bergh, Jee-Hwan Oh, Annika Lundqvist, Tom van Gils, Manuela Krämer, Lisa M. Olsson, Piyush Patel, Matthias Mitteregger, Daysi Espinola Monges, Chinmay Dwibedi, Kimberly A. Krautkramer, Nienke Koopman, Marcus Henricsson, Gianfranco Grompone, Valentina Tremaroli, Magnus Simrén, Fredrik Bäckhed, The Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, 413 45 Gothenburg, Sweden Muhammad Tanweer Khan, Gianfranco Grompone, Stefan Roos, BioGaia AB, 112 27 Stockholm, Sweden Jan-Peter van Pijkeren, Department of Food Science, University of Wisconsin-Madison, Madison, WI 53706, USA Chinmay Dwibedi, Department of Clinical Microbiology and Molecular Infection Medicine Sweden (MIMS), Scilifelab, Umeå University, Umeå, Sweden Andrew J. Macpherson, Maurice Müller Laboratories, Departement Klinische Forschung, Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland Thue Schwartz, Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark Stefan Roos, Department of Molecular Sciences, Uppsala BioCenter, Swedish University of Agricultural Sciences, 750 07 Uppsala, Sweden Fredrik Bäckhed, Region Västra Götaland, Sahlgrenska University Hospital, Department of Clinical Physiology, 413 45 Gothenburg, Sweden Fredrik Bäckhed, Novo Nordisk Foundation Microbiome Health Initiative and the National Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark

This article "Spatial metabolic gradients in the liver and small intestine" is published in Nature.Author: Laith Z. Samarah Journal: Nature Year: 2025 Podcast type: ShortThe authors are:Laith Z. SamarahClover ZhengXi XingWon Dong LeeAmichay AfriatUthsav ChitraMichael R. MacArthurWenyun LuConnor S. R. JankowskiCong MaCraig J. HunterMichael NeinastDaniel R. WeilandtBenjamin J. RaphaelJoshua D. RabinowitzAffiliations:Laith Z. Samarah, Clover Zheng, Xi Xing, Amichay Afriat, Michael R. MacArthur, Wenyun Lu, Connor S. R. Jankowski, Cong Ma, Craig J. Hunter, Michael Neinast, Daniel R. Weilandt, Joshua D. Rabinowitz, Department of Chemistry, Princeton University, Princeton, NJ, USA Laith Z. Samarah, Clover Zheng, Xi Xing, Amichay Afriat, Michael R. MacArthur, Wenyun Lu, Connor S. R. Jankowski, Cong Ma, Craig J. Hunter, Michael Neinast, Daniel R. Weilandt, Joshua D. Rabinowitz, Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ, USA Laith Z.Samarah, Clover Zheng, Xi Xing, Amichay Afriat, Michael R. MacArthur, Wenyun Lu, Connor S. R. Jankowski, Cong Ma, Craig J. Hunter, Michael Neinast, Daniel R. Weilandt, Joshua D. Rabinowitz, Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA Clover Zheng, Uthsav Chitra, Cong Ma, Benjamin J. Raphael, Department of Computer Science, Princeton University, Princeton, NJ, USA Won Dong Lee, Department of Biochemistry, Yonsei University, Seoul, South Korea Uthsav Chitra, Eric and Wendy Schmidt Center, Broad Institute of MIT and Harvard, Cambridge, MA, USA

This article "Hijacking a bacterial ABC transporter for genetic code expansion" is published in Nature.Author: Tarun Iype Journal: Nature Year: 2025Podcast type: ShortThe authors are:Tarun IypeMaximilian FottnerPaul BöhmCarlos PiedrafitaYannis MöllerMichael GrollKathrin LangAffiliations:Tarun Iype, Maximilian Fottner, Paul Böhm, Yannis Möller, Kathrin Lang, Department of Chemistry and Applied Biosciences (D-CHAB), ETH Zurich, Zurich, Switzerland Carlos Piedrafita, Michael Groll, Kathrin Lang, Center for Protein Assemblies, TUM School of Natural Sciences, Department of Bioscience, Technical University of Munich, Garching, Germany

This article "Integrated epigenetic and genetic programming of primary human T cells" is published in Nature Biotechnology.Author: Laine GoudyJournal: Nature BiotechnologyYear: 2025Podcast type: ShortThe authors are:Laine GoudyAlvin HaAshir A. BorahJennifer M. UmhoeferLauren ChowCarinna TranAidan WintersAlexis TalbotRosmely HernandezZhongmei LiSanjana SubramanyaAbolfazl ArabNupura KaleJae Hyun J. LeJoseph J. MuldoonChang LiuRalf SchmidtPhilip SantangeloJulia CarnevaleJustin EyquemBrian R. ShyAlex MarsonLuke A. GilbertAffiliations:Laine Goudy, Alvin Ha, Lauren Chow, Carinna Tran, Zhongmei Li, Jae Hyun J. Lee, Joseph J. Muldoon, Justin Eyquem, Brian R. Shy, Alex Marson, Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USALaine Goudy, Ashir A. Borah, Aidan Winters, Abolfazl Arab, Luke A. Gilbert, Department of Urology, University of California, San Francisco, San Francisco, CA, USAAlvin Ha, Lauren Chow, Jae Hyun J. Lee, Brian R. Shy, Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USAJennifer M. Umhoefer, Joseph J. Muldoon, Julia Carnevale, Department of Medicine, University of California, San Francisco, San Francisco, CA, USAAlexis Talbot, Université de Paris Cité, INSERM UMR976, Hôpital St-Louis, Paris, France Ralf Schmidt, Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria Philip Santangelo, Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USAPhilip Santangelo, Department of Chemical Engineering, Georgia Institute of Technology, Atlanta, GA, USAPhilip Santangelo, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USAJulia Carnevale, Justin Eyquem, Brian R. Shy, Alex Marson, Parker Institute for Cancer Immunotherapy, San Francisco, CA, USAJulia Carnevale, Justin Eyquem, Alex Marson, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USAJustin Eyquem, Alex Marson, Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USAAlex Marson, Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA Luke A. Gilbert, Arc Institute, Palo Alto, CA, USA