What leads people to depression? Actually for some people, a negative, stressful, or unhappy family life can lead to depression. Other high-stress living situations — like poverty, homelessness, or violence — can lead to it, too. Dealing with bullying, harassment, or peer pressure also leaves some people feeling alone or anxious…. Depression is a serious condition that affects your physical and mental health. It's treatable and it's worth talking to someone about it…