Overview: In this podcast, hear from someone who will share his personal experiences with brain aneurysm diagnosis, treatment, and management — offering valuable insights into what primary care physicians can do to identify and refer patients with brain aneurysms before rupture occurs.

Overview: Listen in as expert faculty explore the neuroendocrine drivers of vasomotor symptoms (VMS)—including the KNDy neuron system—and review the efficacy and safety of emerging nonhormonal treatments. Expand your toolkit to deliver more informed, up-to-date care to patients experiencing menopause.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-492 Overview: Small lifestyle changes can yield outsized results—and primary care clinicians are ideally positioned to drive that change. This episode explores the synergistic effects of the SPAN approach on lifespan and provides actionable strategies for guiding patients toward sustainable habits that improve long-term health. Episode resource links: Koemel, et al; eClinicalMedicine, Volume 0, Issue 0, 103741, 2026 Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-491 Overview: Pulse oximetry is a cornerstone of patient monitoring, but limits to its accuracy can lead to important clinical implications. Tune in as we discuss the factors that can compromise oximetry accuracy—including skin tone—so you can make more informed, individualized treatment decisions. Episode resource links: Martin DS, Doidge JC, Gould D, et al. The impact of skin tone on performance of pulse oximeters used by NHS England COVID Oximetry @home scheme: measurement and diagnostic accuracy study. BMJ. 2026;392:e085535. Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-490 Overview: In the US, maternal morbidity and mortality rates are among the highest in the western world, and stroke is one of the leading causes—responsible for 1 of 12 maternal deaths. This rate is estimated to be much higher in high-risk pregnancies. Join us as we discuss a recent study examining rates of maternal stroke in which 1 in 4 women with stroke experienced a missed diagnostic opportunity and hear what these findings mean for your practice. Episode resource links: Haghighi N, Bourscheid RM, Shang C, et al. Identifying missed diagnostic opportunities in maternal stroke. Stroke. 2026;57(2). doi:10.1161/STROKEAHA.125.052995 Chen Y, Shiels MS, Uribe-Leitz T, et al. 2025. Pregnancy-Related Deaths in the US, 2018-2022. JAMA Network Open.  Lappen JR, Pettker CM, Louis JM. 2021. American Journal of Obstetrics and Gynecology. Society for Maternal-Fetal Medicine Consult Series #54: Assessing the Risk of Maternal morbidity and Mortality. American Journal of Obstetrics and Gynecology. Miller EC, Bello NA, Chen PR, et al 2026. Prevention and Treatment of Maternal Stroke in Pregnancy and Postpartum: A Scientific Statement from the American Heart Association. Stroke.  Bushnell C, Kernan WN, Sharrief AZ, et al. 2024. Guideline for the Primary Prevention of Stroke: A Guideline from the American Heart Association/¬American Stroke Association. Stroke.  Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-489 Overview: Join us as we discuss lipoprotein(a) testing—including when it adds value and when it may not. We review the evidence behind this increasingly requested cardiovascular risk marker, equipping you with the knowledge to counsel patients, understand current and emerging treatment options, and optimize evidence-based strategies to reduce overall cardiovascular disease risk. Episode resource links: Eur J Clin Invest. 2025 Oct 3:e70127. doi: 10.1111/eci.70127. Arterioscler Thromb Vasc Biol. 2022 Jan;42(1):e48-e60. doi: 10.1161/ATV.0000000000000147Progress in Cardiovascular Diseases, 84, 2024, Pages 27-33, https://doi.org/10.1016/j.pcad.2024.05.007 Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-488 Overview: Stimulants have long been used to treat attention-deficit/hyperactivity disorder (ADHD); however, their mechanisms of action have been unclear. In this episode, we review a study on functional MRI to assess brain function in patients with ADHD, providing insight into the effects of stimulant medications. Episode resource links: https://doi.org/10.1016/j.cell.2025.11.039 Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-487 Overview: With online access driving a dramatic surge in gambling addiction, primary care clinicians are increasingly positioned on the front lines of identification and intervention. This episode brings you practical screening tools, evidence-based treatment strategies, and prevention approaches to confidently address gambling disorder in your patients. Episode resource links: Yeola A, Allen MR, Desai N, et al. Growing Health Concern Regarding Gambling Addiction in the Age of Sportsbooks. JAMA Intern Med. 2025;185(4):382–389. doi:10.1001/jamainternmed.2024.8193 Moreira D, Azeredo A, Dias P. Risk Factors for Gambling Disorder: A Systematic Review. J Gambl Stud. 2023;39(2):483-511. doi:10.1007/s10899-023-10195-1 Ioannidis K, Del Giovane C, Tzagarakis C, et al. Pharmacological management of gambling disorder: A systematic review and network meta-analysis. Compr Psychiatry. 2025;137:152566. doi:10.1016/j.comppsych.2024.152566 Ulisse, K., Albitar, J., Aromin, J. T., & Berry, J. (2025). Emerging Interventions in Behavioral Addictions: A Narrative Review of Psychedelics and Neuromodulation. Brain sciences, 15(9), 980. https://doi.org/10.3390/brainsci15090980   Identifying a gambling disorder:  Mass.gov Practice Guidelines for Treating Gambling-Related Problems.  Includes brief screening, Assessment, Diagnosis, Hotlines and Resources.  Gambling Addiction Calendar:  Free app  Reset App: Free Guest: Jill M. Terrien PhD, ANP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-486 Overview: Optimizing diabetes management starts with choosing the right medication for the patient. Listen in as we discuss current prescribing recommendations, empowering you to confidently compare medication classes and select therapies that best fit individual patient needs—while prioritizing kidney protection to reduce the risk of long-term complications. Episode resource links: Jensen SK, Heide-Jørgensen U, Andersen IT, et al. SGLT2 Inhibitors vs GLP-1 Receptor Agonists for Kidney Outcomes in Individuals With Type 2 Diabetes. JAMA Intern Med. Published online January 20, 2026. doi:10.1001/jamainternmed.2025.7409 Samson SL, et al. American Association of Clinical Endocrinology consensus statement: comprehensive type 2 diabetes management algorithm—2023 update. Endocr Pract. 2023;29(5):305-340. Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-485 Overview: Teenagers are at higher susceptibility for hearing loss and often engage in behaviors that greatly increase their risk of permanent damage. In this episode, we look at current prevalence data and the pathophysiology of adolescent hearing loss, providing practical, office-ready prevention strategies to identify at-risk teens and intervene early. Episode resource links: Reijers SNH, Vroegop JL, Paping DE, Pronk M, Goedegebure A, Kremer B, van der Schroeff MP. Longitudinal Insights into Sensorineural and Noise-Induced Hearing Loss in Adolescents Aged 13-18 Years. Otolaryngol Head Neck Surg. 2025 Dec;173(6):1385-1392. doi: 10.1002/ohn.70042. Epub 2025 Oct 14 Byeon H. Associations between adolescents' earphone usage in noisy environments, hearing loss, and self-reported hearing problems in a nationally representative sample of South Korean middle and high school students. Medicine (Baltimore). 2021 Jan 22;100(3):e24056. doi: 10.1097/MD.0000000000024056. Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.