Summary In this episode, Dr. K and Kyle discuss the benefits and applications of methylene blue, one of the oldest drugs in the world. They explore its history as a dye and its use as an anti-malarial drug. The conversation delves into the dosing and administration of methylene blue, including the differences between oral and IV administration. They also discuss the importance of obtaining high-quality methylene blue and the potential side effects and contraindications. The episode concludes with a discussion on the various uses of methylene blue in treating different conditions and the potential synergistic effects with light activation. This podcast episode provides a comprehensive exploration of methylene blue, covering its side effects, how it acts on the brain, drug interactions and precautions, the impact on urine color, duration of urine color change, interaction with vitamin C, personal experiences, its potential for weight loss, and its historical use. Takeaways Methylene blue can cause side effects such as gastrointestinal issues and dizziness when taken orally, and muscle cramping and dizziness when administered intravenously. Methylene blue acts on the blue spot in the brain, which helps regulate serotonin levels. It is important to be cautious when taking methylene blue with medications or substances that modulate serotonin, as it can lead to serotonin syndrome. Chapters Sponsors This episode is sponsored by Toxic Roots.  The optimal resource for online health coaching for optimizing performance and removing toxins. Click on the link below to get started on finding your toxic roots.  Website: https://www.toxicrootswellness.com/ Instagram: https://www.instagram.com/toxicrootswellness/ X https://twitter.com/toxicroots Sources Study on IV vs Oral MB https://pubmed.ncbi.nlm.nih.gov/10952480/ Book on MB by Dr. John Lieurance https://www.drjohnlieurance.com/product-page/methylene-blue Socials Peak Performance  Website: https://peakperformancepodcast.online/ On Instagram: https://www.instagram.com/thepeakperformancepod/ On X https://twitter.com/PeakPerformPod Dr. K  On Instagram https://www.instagram.com/theosteodoc/ Coach Kyle  On Instagram https://www.instagram.com/toxinfreekyle/ Dr. John Lieurance On Instagram https://www.instagram.com/drjohnlieurance/?hl=en