Neuromod Nerds
Neuromod Nerds
Matt Custodero
A podcast covering current events in the neuromodulation space, including but not limited to clinical trials, industry news, and new tech. Have any interesting topics / ideas? Or want to join the podcast? Please email me at [email protected].
A Discussion on Neurofeedback with Dr. Giancarlo Licata
Want to be on the show or have questions? Email Me! [email protected] Today's episode is a unique one, and one that I think you will enjoy regarding neurofeedback; differentiating terminology and even misconceptions to make sense of a fascinating neuromodulation therapy. This episode features a resident expert in the field of neurofeedback, Dr. Giancarlo Licata. Sources: https://pubmed.ncbi.nlm.nih.gov/30862532/ https://pubmed.ncbi.nlm.nih.gov/29432505/ https://pubmed.ncbi.nlm.nih.gov/34776024/ https://tnnfb.com/?gclid=CjwKCAjwue6hBhBVEiwA9YTx8CxI0LW53amXrIaXUa-8Yqhg2yFk13TjOeg0TvU_Dk5gS6VLmsKknhoCZKgQAvD_BwE https://www.sciencedirect.com/topics/neuroscience/transcranial-alternating-current-stimulation https://www.sciencedirect.com/topics/medicine-and-dentistry/transcranial-direct-current-stimulation https://www.sciencedirect.com/topics/neuroscience/transcranial-magnetic-stimulation https://my.clevelandclinic.org/health/treatments/13354-biofeedback
Apr 17, 2023
35 min
The SOLIS Trial, Eterna IPG, and SCS for Post-Stroke Motor Function
Want to be on the show or have questions? Email Me! [email protected] Today's episode discusses all things spinal cord stimulation, including exciting industry updates, the perils of insurance approvals, and new research that sets to expand upon current SCS concepts. Sources for the SOLIS Trial: https://neuronewsinternational.com/boston-scientific-solis-rct-nans-2023/ https://anesthesiology.weill.cornell.edu/research/anesthesiology-clinical-trials/clinical-trials-directory/a-randomized-controlled-study-to Sources for Eterna IPG: https://www.neuromodulation.abbott/us/en/chronic-pain/how-neurostimulation-treats/eterna-scs-system.html https://abbott.mediaroom.com/2022-12-19-Abbott-Launches-the-Worlds-Smallest-Implantable,-Rechargeable-Spinal-Cord-Stimulation-System-for-Chronic-Pain Sources for Post-Stroke SCS: https://neuronewsinternational.com/spinal-cord-stimulation-instantly-improves-arm-hand-mobility-stroke/ https://microtransponder.com/en-gb/stroke/physicians/stroke-technology https://nrtimes.co.uk/spinal-stimulation-improves-arm-function-after-stroke-ststory23/
Mar 20, 2023
9 min
Peripheral Nerve Stimulation for Chronic Pain
Want to be on the show or have questions? Email Me! [email protected] Today's episode discusses the two unique neuromodulation approaches to treat patients battling chronic pain Sources: https://www.neurosurgery.columbia.edu/patient-care/treatments/peripheral-nerve-stimulation https://www.youtube.com/watch?v=jpn2uQyAc_c https://www.youtube.com/watch?v=r3tGS-HwyIc&t=22s https://www.sprtherapeutics.com/sprint-pns-system/ https://www.futuremedicine.com/doi/10.2217/pmt-2022-0005#:~:text=60%2Dday%20PNS%20treatment%20outcomes&text=At%20the%20end%20of%20the,subgroup%20(Figure%202A). https://www.clinicaltrials.gov/ct2/show/NCT05287373 https://nalumed.com/patients/peripheral-nerve-stimulator/ https://www.youtube.com/watch?v=dEdKnm7h5co&t=246s
Feb 19, 2023
10 min
Baroreflex Activation Therapy vs. Cardiac Contractility Modulation
Want to be on the show or have questions? Email Me! [email protected] Today's episode discusses the two unique neuromodulation approaches to treat heart failure.  Sources : https://www.youtube.com/watch?v=Kmbw77fEDek&t=702s https://www.youtube.com/watch?v=EUAZNNJRzoA https://pubmed.ncbi.nlm.nih.gov/32264716/ https://www.jacc.org/doi/abs/10.1016/j.jacc.2020.05.015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655601/
Jan 25, 2023
12 min
Understanding the EVOKE Trial and the History of Spinal Cord Stimulation
Want to be on the show or have questions? Email Me! [email protected] Sources: https://pubmed.ncbi.nlm.nih.gov/31870766/ https://www.frontiersin.org/articles/10.3389/fnins.2017.00339/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359972/pdf/PAPR-21-680.pdf https://jamanetwork.com/journals/jamaneurology/article-abstract/2788004 https://www.prnewswire.com/news-releases/publication-of-two-year-evoke-double-blind-randomized-controlled-trial-results-in-jama-neurology-demonstrate-sustained-superiority-of-evoke-closed-loop-over-open-loop-spinal-cord-stimulation-301456813.html#:~:text=Significant%20findings%20of%20Evoke%20ECAP,84%25%20and%2050%25%2C%20respectively https://www.saludamedical.com/us/evidence For Gate Control Theory: https://www.physio-pedia.com/Gate_Control_Theory_of_Pain#:~:text=The%20Gate%20Control%20Theory%20of,be%20let%20through%20or%20restricted.
Dec 23, 2022
9 min
Neuromodulation to Treat Cerebral Palsy
Want to be on the show or have questions? Email Me! [email protected] Sources: https://www.biospace.com/article/releases/spinex-receives-fda-breakthrough-device-designation-for-scip/ https://spinalnewsinternational.com/spinex-demonstrates-novel-technology-to-treat-children-with-cerebral-palsy/ https://www.nature.com/articles/s41467-022-33208-w https://physicsworld.com/a/non-invasive-neuromodulation-improves-motor-function-in-children-with-cerebral-palsy/ https://www.mayoclinic.org/diseases-conditions/cerebral-palsy/symptoms-causes/syc-20353999
Nov 21, 2022
6 min
Understanding and Comparing Vagal Nerve Stimulation and Restorative Neuromodulation
Want to be on the show or have questions? Email Me! [email protected] Sources for VNS: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017164/ https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulation https://onlinelibrary.wiley.com/doi/10.1002/9781118346396.ch13#:~:text=Summary,levels%20in%20the%20brain%20stem. Sources for RNS: https://www.medscape.com/viewarticle/818699_2#:~:text=There%20are%20many%20important%20differences,epileptic%20foci%20in%20the%20brain. https://www.neuropace.com/patients/neuropace-rns-system/ https://clinicaltrials.gov/ct2/show/NCT05147571 https://www.medicaldevice-network.com/news/neuropaces-rns-system-trial/
Oct 31, 2022
5 min
Understanding and Treatment of Spinal Cord Injury
Sources:  https://www.shepherd.org/patient-programs/spinal-cord-injury/levels-and-types https://www.mayoclinic.org/diseases-conditions/spinal-cord-injury/symptoms-causes/syc- 20377890https://www.businesswire.com/news/home/20221004005827/en/ONWARD-Announces-Topline-Results-from-the-LIFT-Home-Study-Supporting-Safety-and-Feasibility-of-ARC-EX-Therapy-to-Treat-People-with-Spinal-Cord-Injury-at-Home https://clinicaltrials.gov/ct2/show/NCT02936453 https://www.nature.com/articles/s41591-021-01663-5
Oct 10, 2022
6 min
The SAINT Trial, tACS, and the Business Behind Neuromodulation
Want to be on the show? Email me! [email protected]  Sources: SNT: https://www.psychiatryadvisor.com/home/topics/mood-disorders/depressive-disorder/fda-clears-saint-neuromodulation-system-for-major-depressive-disorder/ https://www.medicaldevice-network.com/news/magnus-saint-neuromodulation-system-fda/ https://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2021.20101429 TACS: https://www.lifespan.io/news/neuromodulation-improves-memory-in-older-adults/ https://www.nature.com/articles/s41593-022-01132-3#Tab1 Business: https://www.globenewswire.com/en/news-release/2022/09/05/2509762/0/en/Neuromodulation-Devices-Market-to-Hit-14-16-Billion-by-2030-Growing-at-a-CAGR-of-10-29.html
Sep 19, 2022
7 min
tDCS, New SCS System, and BCI's
Sources for tDCS: https://www.frontiersin.org/articles/10.3389/fneur.2022.849820/full https://neuronewsinternational.com/randomised-data-support-use-of-tdcs-in-parkinsons-patients-with-pisa-syndrome/ https://www.hopkinsmedicine.org/psychiatry/specialty_areas/brain_stimulation/tdcs.html Sources for SCS: https://www.prnewswire.com/news-releases/fda-approves-abbotts-new-spinal-cord-stimulation-device-provides-tailored-relief-to-multiple-pain-areas-and-adds-more-treatment-options-for-evolving-pain-conditions-301610549.html https://www.fiercebiotech.com/medtech/abbott-proclaims-fda-approval-neurostimulator-treat-pain-six-areas-once Sources for BCI's: https://www.psychologytoday.com/us/blog/the-future-brain/202208/first-human-us-implant-synchron-brain-computer-interface https://www.sciencedirect.com/topics/neuroscience/brain-computer-interface https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862632/#:~:text=The%20most%20common%20example%20of,without%20using%20conventional%20neuromuscular%20pathways.
Sep 2, 2022
5 min