Dr. Howard Sesso of Harvard explains the results of the COSMOS trial, identifying who actually benefits from a daily multivitamin and how it impacts biological aging.
Is a daily multivitamin a life-extending "insurance policy" or just a waste of money? In this clip, Dr. Howard Sesso, Co-Principal Investigator of the landmark COSMOS trial, breaks down the clinical evidence from over 21,000 participants. We explore the "sweet spot" of nutritional insufficiency; where you aren't clinically deficient but lack the levels needed for optimal healthspan.
Dr. Sesso and Dr. Sidong Li discuss how multivitamins specifically slowed the "epigenetic clock" in individuals with existing risk factors like hypertension and accelerated biological aging. We also cover the importance of "precision nutrition" and why the synergy of essential vitamins and minerals may be more effective than high-dose single supplements. If you’re looking for a common-sense, evidence-based approach to basic supplementation, this deep dive into the Harvard-led COSMOS data provides the answers you need.
🌐Links in this video
COSMOS Trial home page https://cosmostrial.org/ Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial https://www.nature.com/articles/s41591-026-04239-3
Time-Line Mitopure Urolithin A, 10% off Code MODERN https://tidd.ly/4bLCpgu
Qitone (10% off: HEALTH10) https://tidd.ly/4jGklry Qitone Esters Powder
Seeking Health supplements: 10% discount code Richard10 https://crrnt.app/SEEK/-dm0MyrQ, Histamine Nutrients https://crrnt.app/SEEK/EpM7paAO
AX3 Life Astaxanthin 20% discount code MODERN20 https://tinyurl.com/2t3w26nw
https://www.choosemuse.com
Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US)
Renue by Science all 10% discount with code MHS https://renuebyscience.com/
Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MODERN
If you would like to support our channel please consider signing up on patreon https://patreon.com/ModernHealthspan
You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan
