Could a ketogenic diet and low-dose GLP-1 medications work better together? A new case series suggests they might, while highlighting a more personalized approach to metabolic health.GLP-1 medications have transformed obesity treatment, but they aren't the only tool available. In this interview, Dr. Bret Scher speaks with physician assistant Bill Jensen about a newly published case series exploring the combination of a ketogenic diet and low-dose semaglutide. Together, they discuss how this approach may help preserve lean mass, improve insulin resistance, reduce side effects, and empower patients to take an active role in their health.In this video:Why low-dose GLP-1s may complement a ketogenic dietThe importance of preserving muscle during weight lossWhich patients may benefit most from this approachWhy this case series is hypothesis-generating, not definitiveHow lifestyle and medication can work together to improve metabolic healthThis conversation examines how a more personalized approach to care could improve long-term health outcomes. Rather than asking whether medication or lifestyle is "better," it explores how combining the right tools for the right person may help improve body composition, support metabolic health, and empower patients to play an active role in their care.💡 Not all ketogenic diets are the same. If you’re interested in learning more about what a well-formulated ketogenic diet looks like, check out our blog: Understanding the Well-Formulated Ketogenic Diet.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #GLP1Expert Featured:Bill Jenson PA-C, MMShttps://www.summitfamilyhealth.org/dr-jensenhttps://www.linkedin.com/in/william-jensen-45027053/https://www.instagram.com/summitmetabolichealth/Resources Mentioned:Personalized Combination of a Ketogenic Diet and Low-Dose Semaglutide for Cardiometabolic Health: A Retrospective Case Serieshttps://doi.org/10.3390/jpm16060313Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

What does it take to truly understand and assess cardiovascular risk in modern medicine?Dr. Bret Scher joins Dr. Ford Brewer at the Collaborative Science (CoSci) conference to discuss the recent screening of The Cholesterol Code documentary and the bigger picture of metabolic health, cardiac imaging, and the future of risk assessment.In this conversation, you'll learn:Dr. Ford Brewer's reaction to The Cholesterol Code documentary and what stood out mostWhy metabolism, not just plumbing, drives cardiovascular diseaseHow CT angiogram with AI analysis is becoming the gold standard in cardiac imagingWhat CIMT (Carotid Intima-Media Thickness) measures and where it fits in evaluating riskWhy calcium scores can miss important soft plaqueWhat to look for when seeking a high-quality CIMT scanDr. Brewer's personal story of being diagnosed with manic depression in medical school and how lifestyle and metabolic changes shaped his journeyWhy GLP-1 medications, when used responsibly, can be a useful tool rather than a stand-alone solutionHow the overuse of statins and GLP-1s reflects broader issues in modern medicineThis discussion captures the value of bringing nuanced, individualized thinking into the conversation around cardiovascular risk, metabolic health, and mental wellness.🔎 Learn more about CIMT tests on our blog: Early Heart Disease Detection? Why You May Consider a CIMT Test🎥 Watch The Cholesterol Code documentary and join the conversation shaping the future of metabolic health: https://www.youtube.com/watch?v=57Z8bUb1P94#MetabolicMind #KetogenicTherapy #HeartDiseaseExpert Featured:Dr. Ford Brewerhttps://prevmedhealth.com/https://www.youtube.com/channel/UCmoEsq6a6ePXxgZeA4CVrUwhttps://www.instagram.com/brewer.fordhttps://www.linkedin.com/in/fordbrewer/https://www.facebook.com/DrFordBrewer/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Type 2 diabetes is a chronic disease that can often be put into remission. So why do so many people still struggle to get better?In this discussion, Dr. Bret Scher explores how the environments we create, from our food system to our healthcare system, shape metabolic health in ways that are often overlooked.Using a thought experiment as a starting point, he examines why remission is possible for many people with type 2 diabetes, why that shouldn't be confused with 100% personal responsibility, and what needs to change if we want to improve outcomes at scale.He covers:Why type 2 diabetes remission is possible for many peopleHow ketogenic nutrition and other metabolic therapies can improve insulin resistanceWhy type 1 and type 2 diabetes require fundamentally different approachesHow modern food environments contribute to metabolic dysfunctionThe limitations of decades of conventional nutrition adviceWhy clinician education and public policy matter for metabolic healthHow shifting the conversation from blame to biology can improve patient careGrowing evidence continues to show that metabolic health can be improved through nutrition and lifestyle interventions when people have the right support. Building healthcare systems and food environments that reflect that science could help more people achieve better long-term health.👉 Want to stay up to date with the latest research on metabolic health and metabolic psychiatry? Sign up for our newsletter to stay informed: metabolicmind.org/about-us/newsletter/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #Diabetes #KetogenicTherapyExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Dr. Bret Scher began his career practicing conventional cardiology, following the same guidelines taught in medical training. Today, he is Medical Director at Metabolic Mind, as well as The Coalition for Metabolic Health, and one of the leading voices advancing metabolic health, ketogenic therapy, and metabolic psychiatry.What changed?In this special episode, Metabolic Mind producer Erica Gerard turns the tables and interviews Dr. Scher about the experiences, patients, and pivotal moments that challenged his thinking and reshaped his approach to medicine.In this conversation, you'll learn:How a conventionally trained cardiologist became known as the "low-carb cardiologist"The patients who changed the way he thought about nutrition and metabolic healthWhy he believes medicine should treat individuals, not just follow guidelinesWhat drew him from cardiovascular medicine into the emerging field of metabolic psychiatryHow interviewing researchers, clinicians, and patients has influenced his perspective on evidence and clinical careHis hopes for the future of metabolic health and what it could mean for medicineAlong the way, Dr. Scher shares personal stories from his childhood, medical training, career, and family life, offering a rare look at his curiosity, humility, and willingness to challenge his own assumptions that continue to shape his work today.Whether you've followed Dr. Scher's work for years or meeting him for the first time, this conversation offers insight into the journey behind one of the most trusted voices in metabolic medicine.👉 Learn more about Metabolic Mind, Dr. Scher, and the metabolic psychiatry movement at metabolicmind.org🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatryExpert Featured:Erica Gerard - Metabolic Mind ProducerBret Scher, MD - Medical Director & Host of the Metabolic Mind Podcasthttps://www.linkedin.com/in/bret-scher-08baaa102/https://www.instagram.com/drscher858/?hl=enhttps://x.com/bschermdExpert Mentioned:Dr. Georgia Ede, MD- Author, Change Your Diet, Change Your Mindhttps://www.linkedin.com/in/georgiaedemd/https://x.com/GeorgiaEdeMDhttps://www.instagram.com/georgiaedemd/Dr. Andreas Eenfeldthttps://www.youtube.com/user/eenfeldt/videoshttps://se.linkedin.com/in/dietdoctorJan Ellison Baszuckihttps://www.metabolicmind.org/team/jan-ellison-baszucki/https://www.linkedin.com/in/janellisonbaszuckihttps://www.instagram.com/jan_ellison_baszucki/?hl=enFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

What questions matter most to people living with serious mental illness when it comes to metabolic interventions?Dr. Dina Farran and Dr. Toby Pillinger from King's College London set out to answer exactly that through a Priority Setting Partnership, an extensive collaborative process bringing together people with lived experience, family members, caregivers, clinicians, and researchers to identify the top research priorities in metabolic psychiatry.Their findings reveal a powerful shift in how patients and clinicians think about mental illness, and what the future of treatment may look like.In this conversation, you'll learn:What a Priority Setting Partnership is and why it matters for psychiatric researchHow over 450 participants and 1,400 submissions were narrowed down to a top 10 listWhy 8 of the top 10 priorities focused on mental health outcomes, not just physical healthWhy ketogenic diets ranked as the number one research priorityHow GLP-1 medications, exercise, gut health, and nutrient deficiencies entered the conversationWhy patients and caregivers may have a more integrated view of mental illness than the research fieldWhat this roadmap means for the future of metabolic psychiatry research and careThis interview captures a meaningful turning point in how the field of metabolic psychiatry is beginning to align with what truly matters to the people it serves.Interested in learning more about metabolic psychiatry? Check out our blog: What is Metabolic Psychiatry?🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #MetabolicPsychiatry #KetogenicTherapyExpert Featured:Dr. Dina Farranhttps://uk.linkedin.com/in/dina-farran-225028288Dr. Toby Pillingerhttps://www.kcl.ac.uk/people/toby-pillingerhttp://uk.linkedin.com/in/toby-pillingerResources Mentioned:PSP has been previously run by: https://www.jla.nihr.ac.uk/https://www.nih.gov/Where the manuscript will be published: https://www.thelancet.com/journals/lanpsy/homeExperts mentioned:Danny Smithhttps://edwebprofiles.ed.ac.uk/profile/professor-daniel-j-smithFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

A recent study made headlines for claiming a ketogenic diet may worsen fatty liver disease and raise triglycerides. But when you take a closer look at the research, it’s clear that the conclusions are far less supported than the coverage suggests.To clear things up, Dr. Bret Scher breaks down what the study actually found, where the methodology falls short, and what the broader body of research has to say about ketogenic therapy and liver health.In this discussion, you'll learn:What the study examined and how the data was collectedWhy the lack of ketone measurement makes it impossible to confirm anyone was actually in ketosisHow reverse causality may explain the findings entirelyWhat baseline differences in BMI and adiposity reveal about the study populationWhy cross-sectional observational studies sit lower on the evidence hierarchy than RCTsWhat a meta-analysis of 62 randomized controlled trials shows about ketogenic diets and triglyceridesWhat a 12-week supervised intervention revealed about ketogenic therapy and fatty liver reductionWhy higher-quality controlled trial evidence should take precedence over headline-grabbing observational studiesFor clinicians, researchers, and anyone navigating conflicting headlines about ketogenic therapy, this conversation is a reminder that the quality of evidence matters as much as the findings themselves.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#KetogenicTherapy #MetabolicMind #FattyLiverDiseaseExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Association between dietary patterns and lipid profile in patients with non-alcoholic fatty liver disease: a retrospective cross-sectional studyhttps://doi.org/10.3389/fnut.2026.1794910Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Is a plant-based diet the best for supporting metabolic health? Cardiologist Dr. Jaimela Dulaney spent years practicing plant-based nutrition before her own experience with insulin resistance, blood sugar swings, and endurance running led her to rethink what personalized nutrition can look like.In this episode, Dr. Bret Scher speaks with Dr. Dulaney about what changed her perspective, both personally and professionally.They cover:How CGMs helped reveal unexpected blood sugar patternsWhy insulin resistance can show up even in active, normal-weight individualsHow Dr. Dulaney thinks about LDL cholesterol in the context of metabolic healthWhy low-carb and ketogenic diets may help some people improve energy, recovery, and blood sugar stabilityWhy there may not be one “best diet” for every patientThis conversation highlights the importance of listening to patients, tracking meaningful lab trends, and staying open to new evidence when personal experience and clinical outcomes begin to tell a different story.👉 Interested in learning more about metabolic health, cholesterol, and heart disease? Check out our article: Beyond LDL: New Insights into Metabolic Health and Heart Disease.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #HeartDiseaseExpert Featured:Dr. Jaimela Dulaneyhttps://doctordulaney.com/https://www.youtube.com/@jjd862Expert Mentioned:Andrew Koutnikhttps://www.instagram.com/andrewkoutnikphd/https://www.youtube.com/channel/UCuBoAR4gzVC5Y0e5raQLPkQhttps://www.linkedin.com/in/andrewkoutnikphd111/Dr. Noakeshttps://register.cpso.on.ca/physician-info/?cpsonum=50902https://surgery.utoronto.ca/faculty/jeffrey-noakesResources Mentioned:Additional resourcesDr. Noakes book: Lore of Nutrition: Challenging Conventional Dietary BeliefsDr. Esselstyn - https://www.dresselstyn.com/site/Dean Ornish: Ornish program — http://ornish.com/Nina Teicholz Book: The Big Fat SurpriseFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Metabolic health may be the foundation of a healthy brain, and a growing community of researchers, clinicians, and educators is working to bring that message into mainstream medicine.In this interview, Dr. Bret Scher talks with Dr. Dom D'Agostino at the Citizen Science Initiative (CoSci) conference to discuss everything from the recent screening of The Cholesterol Code documentary to the rise of N-of-1 research, the future of metabolic psychiatry, and the urgent need for nutrition education in medical schools.In this conversation, you'll learn:Dr. D'Agostino’s reaction to The Cholesterol Code documentary and what stood out mostHow N-of-1 citizen science is reshaping the way we think about metabolic healthWhy metabolic health may be a stronger predictor of cardiovascular outcomes than LDL aloneHow nutrition education made its way into the USF College of Medicine curriculumWhat the latest research is revealing about ketogenic metabolic therapy and cancer, brain health, and immune functionWhy metabolic psychiatry is one of the most exciting emerging fields in medicineHow exogenous ketones and ketogenic diets fit into clinical practice and ongoing researchThis discussion offers a thoughtful look at where metabolic medicine is headed and why prioritizing whole-body health is becoming central to supporting the brain.🎥 Watch The Cholesterol Code documentary and join the conversation shaping the future of metabolic health: amazon.com/gp/video/detail/B0GS8ZFCYN/ref=atv_dp_share_cu_r#MetabolicMind #KetogenicTherapy #FoodAsMedicine🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Dominic D’Agostinohttps://drdominicdagostino.com/https://www.instagram.com/dominic.dagostino.kt/?hl=enhttps://www.facebook.com/dominic.dagostino.1/http://linkedin.com/in/dominic-d-agostino-156014bhttps://x.com/DominicDAgosti2?lang=enResources Mentioned:https://www.metabolicinitiative.com/https://www.youtube.com/playlist?list=PL27U85_g28NlX2RAWCiz6us2SW_9OW4VAFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

New results from first-of-its-kind randomized controlled trial on a ketogenic diet for schizophrenia and bipolar disorder with psychosis offer important insights into metabolic psychiatry and mental health treatment.In this interview, Dr. Bret Scher sits down with Dr. Julie Milder to walk through the study results, recently published in Schizophrenia Bulletin. As the first RCT in psychosis-spectrum conditions to publish in the peer-reviewed literature, it’s an important step toward understanding how metabolic interventions may play a role in serious mental illness.Key insights from the study:In the 1-month randomized portion of the trial, the ketogenic group showed significant improvements in metabolic health markers compared to diet-as-usualPsychiatric symptoms trended toward improvement, but were not statistically significant at 1 monthParticipants who opted into the ketogenic extension part of the study (4 total months of keto), saw improvements in depression, cognition, and positive and negative symptoms.In this video, Dr. Milder also breaks down important additional context about the limitations of the study, including the length of the randomized portion of the trial and the variance in dietary support between the two diet groups.This study adds to growing evidence linking metabolic health and psychiatric conditions and explores whether ketogenic therapy may play a role in addressing underlying mechanisms.👉 Want to learn more about the trial? Visit our study page: https://www.metabolicmind.org/trials/featured-post/peer-reviewed-results-of-first-ever-randomized-controlled-trial-of-ketogenic-diet-in-schizophrenia-spectrum-and-bipolar-i-disorder/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Julie MilderBaszucki Group Director of Neurosciencehttp://linkedin.com/in/juliemilderDr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Metabolic improvements with a ketogenic diet correlate with symptom improvement in psychosis: A randomized controlled trialhttps://doi.org/10.1093/schbul/sbag082Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

New evidence from the first-ever RCT shows ketogenic therapy can rapidly improve metabolic health in schizophrenia-spectrum and bipolar I disorders, and shows early signals of psychiatric improvement.In this video, Dr. Bret Scher breaks down this newly published study led by Dr. Judith Ford at UCSF: the first randomized controlled trial with peer-reviewed results investigating ketogenic therapy in people with schizophrenia-spectrum disorders and bipolar-1 disorder with psychotic features.You’ll learn:How the study was designed (a 1-month randomized phase plus an optional 3-4 month single-arm extension)What happened in the first 30 days (clear improvements in metabolic markers; psychiatric outcomes showed trends that did not reach statistical significance in the randomized portion)What improved over longer follow-up in the extension phase (encouraging changes in metabolic health, cognition, and psychiatric measures)Why this matters for patients and families today, and what future, longer controlled trials need to confirmPublished in Schizophrenia Bulletin and funded by the NIMH and Baszucki Group, this study adds to the growing literature on the potential benefit of ketogenic therapy for psychiatric disorders.These results indicate the need for larger, extended randomized controlled trials to test the safety and efficacy of ketogenic therapy in patients living with serious mental illness.👉 Learn more about the study by visiting our website: https://www.metabolicmind.org/trials/featured-post/peer-reviewed-results-of-first-ever-randomized-controlled-trial-of-ketogenic-diet-in-schizophrenia-spectrum-and-bipolar-i-disorder/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Bret Scher, MD, FACCBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Metabolic improvements with a ketogenic diet correlate with symptom improvement in psychosis: A randomized controlled trialhttps://doi.org/10.1093/schbul/sbag082Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.