Weight-loss drugs that target the hormone GLP-1 have rapidly reshaped the conversation around obesity, appetite and personal responsibility. But alongside the rise of powerful synthetic injectables, researchers are also exploring whether the body’s own appetite signals can be harnessed more naturally. At the heart of the debate is a simple question: are we eating too much because of weak willpower, or because of biology? As new approaches emerge, the challenge is to balance effectivenes...