Learning With Lowell
Learning With Lowell
Lowell Thompson
Aubrey De Grey:longevity escape velocity, longevity, mouse rejuvenation, Altos Labs, Yamanaka factor – 148
1 hour 11 minutes Posted Jan 3, 2023 at 10:58 pm.
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Mark Hamaleinen write in question: Why we still don't have any therapies based on his ideas published 20 years ago in his breakout paper
update on escape velocity. 50% in 15 years.
Experiments on mice
Yamanaka factor thoughts, current research on mice continued
Lev foundation research expanded and explained
Lev foundation thesis compared to others 
Hardships being at the tip of the innovation field of longevity
Open source, non profits, lev foundation
Ideas from previous organizations (ie. SENS) applied in LEV
Ichor therapeutics, and partnership process of LEV
Next generation mentorship
Summer internship program
Bullish on longevity
AI role in longevity
Anything fundamental making longevity therapies only for the rich
Longevity surgery therapies
Advice for people
Bottlenecks of longevity
Books!
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Show notes
Aubrey De Grey discusses the progress and potential of therapies related to his ideas on anti-aging medicine, including the four therapies that will be tested in a mouse rejuvenation trial. He also shares his thoughts on partnering with organizations and individuals in the field, integrating AI into his work, and the importance of structure in maximizing impact. Aubrey De Grey discusses the potential for Yamanaka factors to be used in organ rejuvenation, and the role of transcription factors in creating induced pluripotent stem cells. He also provides advice for those interested in getting involved in the field and shares his views on time management and productivity. Aubrey De Grey discusses the potential for reversing the pathology of aging to address mechanical issues and mentions promising research being conducted by MAIA Biotechnology on cancerous cells that express telomerase. He also expresses his optimism about the possibility of reaching "longevity escape velocity" within the next 15 years.
Youtube:
https://youtu.be/DHvoPlcWwg4
Aubrey De Grey links
https://twitter.com/aubreydegrey?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor
https://www.levf.org/
https://www.linkedin.com/in/aubrey-de-grey-24260b/
PODCAST INFO:
The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups.
LINKS
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Website: https://www.learningwithlowell.com/
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