Huberman Lab
Huberman Lab
Mewil
Essentials: Control Your Brain Chemistry for Focus, Motivation & Well-Being
34 minutes Posted Aug 6, 2026 at 8:00 am.
In this Huberman Lab Essentials episode, I explain how key neuromodulators shape motivation, energy, focus and mood throughout the day. I also describe a toolkit of science-supported behavioral, nutritional and supplement-based strategies to increase baseline levels for each neuromodulator, which can be modified to support your specific health and performance goals. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman Timestamps
Optimize Neurochemicals for Health
Neuromodulator Levels & 3 Daily Phases
Hormones Modulate Neuromodulators
Sponsor: Eight Sleep
Effects of Key Neuromodulators
Increase Motivation & Dopamine, Tools: Morning Sunlight; Caffeine
Dopamine Supplements: Mucuna Pruriens, L-Tyrosine, Phenethylamine (PEA)
Increase Dopamine, Tool: Deliberate Cold Exposure
Sponsor: AG1
Increase Epinephrine (Adrenaline) & Energy, Tools: Exercise, Cyclic Hyperventilation
Enhance Focus & Acetylcholine: Choline-Rich Foods, Nicotine
Acetylcholine Supplements: Alpha-GPC, Huperzine
Sponsor: ROKA
Serotonin & Mood, Tools: Gratitude, Tryptophan-Rich Foods
Serotonin Supplement: Myo-inositol
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Show notes
In this Huberman Lab Essentials episode, I explain how key neuromodulators shape motivation, energy, focus and mood throughout the day. I also describe a toolkit of science-supported behavioral, nutritional and supplement-based strategies to increase baseline levels for each neuromodulator, which can be modified to support your specific health and performance goals. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman Timestamps (00:00:00) Optimize Neurochemicals for Health (00:00:27) Neuromodulator Levels & 3 Daily Phases (00:05:07) Hormones Modulate Neuromodulators (00:06:56) Sponsor: Eight Sleep (00:08:13) Effects of Key Neuromodulators (00:10:16) Increase Motivation & Dopamine, Tools: Morning Sunlight; Caffeine (00:13:30) Dopamine Supplements: Mucuna Pruriens, L-Tyrosine, Phenethylamine (PEA) (00:16:34) Increase Dopamine, Tool: Deliberate Cold Exposure (00:19:18) Sponsor: AG1 (00:20:31) Increase Epinephrine (Adrenaline) & Energy, Tools: Exercise, Cyclic Hyperventilation (00:24:56) Enhance Focus & Acetylcholine: Choline-Rich Foods, Nicotine (00:27:11) Acetylcholine Supplements: Alpha-GPC, Huperzine (00:28:05) Sponsor: ROKA (00:29:21) Serotonin & Mood, Tools: Gratitude, Tryptophan-Rich Foods (00:31:49) Serotonin Supplement: Myo-inositol (00:32:26) Using the Neurochemical Toolkit for Your Goals Disclaimer & Disclosures🧬 DOWNLOAD THE PDF SUMMARY:Don't miss the specific dosages and timing protocols discussed today. Get the full visual guide and supplement breakdown here:👇https://goo.su/VOTEbVerified Science Resources.