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How Your Immune System Works & How to Improve It | Dr. Max Krummel
2 hour 27 minutes Posted Aug 3, 2026 at 8:00 am.
My guest is Dr. Matthew (Max) Krummel, PhD, professor at UCSF and one of the world’s leading immunologists. We discuss how your immune system works and how sleep, emotions, and even memories shape immune function. We also explore thymus function, its role in autoimmunity, and its potential role in combating cancer. And we discuss how the type and timing of immunization can impact health. This episode provides an actionable framework for understanding how your immune system works, which ought to benefit people of all ages and health statuses. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Joovv: https://joovv.com/huberman Timestamps
Max Krummel
Immune System, Immunotherapy
Illness, Childhood & Immune System
Aging & Immunity, DNA Mutations
Sponsors: Joovv & Eight Sleep
Self vs Non-Self Recognition, Aging, Cancer; Immune Surveillance
Cancer, Immune System, Age & Measuring Change
Thymus, T Cells; Aging & Cancer
Reproduction, Aging & Immune System; Basic Research
Sleep & Illness Susceptibility
Sponsor: AG1
Umbilical Cord Banking; Organoids, CAR T Cells, Thymus
Scientific Curiosity, Failures, & Discovery
Spatial Biology & Immune Cells; Memory & Immune State; Stress, Meditation
Sponsor: Function
Mindset; Tissue Engineering, Peptides, Systems Biology
Immunizations in Childhood and Beyond
Pharmaceutical Companies, Public Distrust
Disease Risk, Immunity; Autism, Flu,
Biological Resilience, Cancer; Computational Research
Autoimmune Conditions, Asthma, IBD
Autoimmunity & Genetic Diversity Benefits
Science Communication, Max's Substack
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Show notes
My guest is Dr. Matthew (Max) Krummel, PhD, professor at UCSF and one of the world’s leading immunologists. We discuss how your immune system works and how sleep, emotions, and even memories shape immune function. We also explore thymus function, its role in autoimmunity, and its potential role in combating cancer. And we discuss how the type and timing of immunization can impact health. This episode provides an actionable framework for understanding how your immune system works, which ought to benefit people of all ages and health statuses. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Joovv: https://joovv.com/huberman Timestamps (00:00:00) Max Krummel (00:02:18) Immune System, Immunotherapy (00:08:36) Illness, Childhood & Immune System (00:13:02) Aging & Immunity, DNA Mutations (00:18:36) Sponsors: Joovv & Eight Sleep (00:21:14) Self vs Non-Self Recognition, Aging, Cancer; Immune Surveillance (00:30:11) Cancer, Immune System, Age & Measuring Change (00:35:57) Thymus, T Cells; Aging & Cancer (00:42:13) Reproduction, Aging & Immune System; Basic Research (00:47:28) Sleep & Illness Susceptibility (00:52:55) Sponsor: AG1 (00:54:08) Umbilical Cord Banking; Organoids, CAR T Cells, Thymus (01:02:57) Scientific Curiosity, Failures, & Discovery (01:13:14) Spatial Biology & Immune Cells; Memory & Immune State; Stress, Meditation (01:25:00) Sponsor: Function (01:26:37) Mindset; Tissue Engineering, Peptides, Systems Biology (01:34:25) Immunizations in Childhood and Beyond (01:39:37) Pharmaceutical Companies, Public Distrust (01:49:22) Disease Risk, Immunity; Autism, Flu, (01:58:56) Biological Resilience, Cancer; Computational Research (02:08:02) Autoimmune Conditions, Asthma, IBD (02:13:34) Autoimmunity & Genetic Diversity Benefits (02:17:11) Science Communication, Max's Substack (02:24:07) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter🧬 DOWNLOAD THE PDF SUMMARY:Don't miss the specific dosages and timing protocols discussed today. Get the full visual guide and supplement breakdown here:👇https://goo.su/VOTEbVerified Science Resources.