This week Matthew is joined by Harmit Malik, the co-associate director of Basic Sciences at the Fred Hutchinson Cancer Research Center to talk all things heroes, villains, and genomes. Tune in as Harmit walks us through his exploration of genetic conflict and explains its implications for the study of genetic viruses and their hosts. His journey reminds us to stay motivated and trust our instincts when it comes to experimentation.

This week Matthew is joined by Cynthia Kenyon, Vice President of Aging Research at Calico Labs, to discuss all things aging, worms, and proving others wrong. Tune in as Cynthia walks us through her discovery of controlled aging mechanisms and shows how important it is to be unapologetically curious, even in the face of judgement.

This week Matthew is joined by Eva Nogales, a researcher and professor at Berkeley to talk all things microscopes, image analysis, and the future of science. Listen as Eva describes the importance of observation in scientific discovery, and shares stories about how simply looking at something can bring on revelations.

This week Matthew is joined by Jens Holst, a researcher and professor at the University of Copenhagen to talk all things gut hormones, weight-loss, and fighting disease. Listen as Jens describes his discoveries of incretins; a story about starting small, taking incremental steps, working hard to understand the problem deeply.

In this episode, listen as David transports us to his lab where discoveries relating to the mTOR pathway continue to provide key insights about cancer, diabetes, and aging--and learn how hard work can lead to a career of success.

This week Matthew sits down with Bob Lefkowitz, a researcher and professor at Duke University Medical Center, to talk all things receptors, signaling, and drug targeting. Listen as Bob details his discovery of cellular receptors called GPCRs; a story about the countless benefits of focus, rolling with the punches, and most importantly setting up a system to help you achieve your dreams--no matter who or what you're up against.

This week, Matthew sits down with Bruce Spiegelman, a researcher and professor at Harvard Medical School and the Dana-Farber Cancer Institute, to talk all things genes, metabolism, and combatting disease. Listen as Bruce details his discovery of the gene PGC1; a story riddled with high-profile embezzlement, and ultimately triumph.

This week, Matthew shares the apocryphal tale which inspired him to create Heureka podcasts. Listen as he delves into the story of Archimedes and details the lessons we can learn from his discovery.