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Rhonda Patrick, Ph.D.
#085 Dr. Peter Attia on Mastering Longevity – Insights on Cancer Prevention, Heart Disease, and Aging
3 hour 59 minutes Posted Dec 27, 2023 at 4:19 pm.
Download the 9-Page "Cognitive Enhancement Blueprint" Discover my premium podcast The Aliquot Show notes are available by clicking here Peter Attia, MD is a highly respected expert in preventive medicine, focused on the crucial subject of longevity and cardiovascular health. He's also the author of the NY Times best selling book Outlive - which I highly recommend if you have not read it already. Peter's philosophy transcends the conventional goal of merely extending lifespan; it's about enriching the quality of every year, ensuring that each stage of life is lived with optimal health and vitality. In this episode, we discuss:
Introduction
Defining cardiovascular disease
Coronary plaque and fatality risk
How ApoB predicts heart disease
Factors elevating ApoB
Does high ApoB cause cardiovascular disease
ApoB thresholds for ASCVD prevention
Dietary factors raising ApoB
Genetics of ApoB and LDL
Does low LDL increase cancer?
Cholesterol-lowering drugs
Statins, uses, and side effects
Are statins toxic to mitochondria?
Ubiquinol for statin-induced muscle soreness
How to train in zone 2
Statins and neurodegenerative disease risk
Cholesterol synthesis in the brain (desmosterol role)
Statin alternatives
Berberine for CVD Risk Reduction?
Muscle as a glucose sink
Hemoglobin A1C Levels and Mortality Data
80/20 Zone 2/VO2 Max Training Protocol
Insights from VO2 max testing data
How obesity increases cancer risk
Cancer screening
Menopause – hormonal shifts and health effects
Hormone replacement therapy (HRT)
Perimenopause diagnosis with hormone levels
HRT's impact on dementia, cancer, and heart disease risk
Vitamin D
Testosterone replacement for women's sexual function
HRT safety 10 years post-menopause
Testosterone & TRT
Blood pressure
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3:59:02
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Show notes
Download the 9-Page "Cognitive Enhancement Blueprint" Discover my premium podcast The Aliquot Show notes are available by clicking here Peter Attia, MD is a highly respected expert in preventive medicine, focused on the crucial subject of longevity and cardiovascular health. He's also the author of the NY Times best selling book Outlive - which I highly recommend if you have not read it already. Peter's philosophy transcends the conventional goal of merely extending lifespan; it's about enriching the quality of every year, ensuring that each stage of life is lived with optimal health and vitality. In this episode, we discuss: (00:00) Introduction (07:36) Defining cardiovascular disease (09:43) Coronary plaque and fatality risk (13:34) How ApoB predicts heart disease (21:34) Factors elevating ApoB (27:23) Does high ApoB cause cardiovascular disease (37:01) ApoB thresholds for ASCVD prevention (40:27) Dietary factors raising ApoB (49:33) Genetics of ApoB and LDL (53:24) Does low LDL increase cancer? (56:19) Cholesterol-lowering drugs (59:59) Statins, uses, and side effects (1:03:12) Are statins toxic to mitochondria? (1:09:56) Ubiquinol for statin-induced muscle soreness (1:11:09) How to train in zone 2 (1:17:09) Statins and neurodegenerative disease risk (1:21:54) Cholesterol synthesis in the brain (desmosterol role) (1:25:58) Statin alternatives (1:36:49) Berberine for CVD Risk Reduction? (1:39:36) Muscle as a glucose sink (1:51:38) Hemoglobin A1C Levels and Mortality Data (1:55:35) 80/20 Zone 2/VO2 Max Training Protocol (2:02:12) Insights from VO2 max testing data (2:12:17) How obesity increases cancer risk (2:15:03) Cancer screening (2:40:32) Menopause – hormonal shifts and health effects (2:45:13) Hormone replacement therapy (HRT) (2:58:57) Perimenopause diagnosis with hormone levels (3:02:04) HRT's impact on dementia, cancer, and heart disease risk (3:07:42) Vitamin D (3:16:24) Testosterone replacement for women's sexual function (3:18:47) HRT safety 10 years post-menopause (3:23:05) Testosterone & TRT (3:32:33) Blood pressure (3:45:30) Peter's longevity optimization routines Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/premium