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Rhonda Patrick, Ph.D.
#077 Rewriting genomes to eradicate disease and aging | Dr. George Church
2 hour 8 minutes Posted Aug 24, 2022 at 11:00 am.
George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology. In this episode, we discuss:
Introduction to Dr. George Church
History of the Human Genome Project
Manufacturing cell phones (with biology)
Genome Project-Write
Writing a human Y chromosome (from scratch)
What if you could eliminate viral disease?
De-extinction and reinstating lost traits and genes
The Vertebrate Genomes Project
AlphaFold and other AI tools
CRISPR vs. Base Editing (emerging tools of genetic engineering)
Why multiplex editing will change the world
Molecular flight recorder
Preventing viral spillover and enhancing livestock
PCSK9 gene therapy for cholesterol
Is aging an evolved program?
Treating aging with a combination gene treatment
Does animal research help us understand human aging?
Human organoids as a model and therapeutic
Could engineered transplant organs become better than the originals?
Embryo editing controversy
Gene editing for space travel
Can synthetic biology alleviate poverty?
Is in vitro fertilization and embryo selection practically similar to editing?
The occasional cost of brilliance
Eradicating disease with Gene Drive
Technologies to solve Lyme disease
Dr. Church's experience with narcolepsy as a bridge to creative insights
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Show notes
George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology. In this episode, we discuss: (00:00) Introduction to Dr. George Church (07:13) History of the Human Genome Project (15:20) Manufacturing cell phones (with biology) (17:34) Genome Project-Write (20:03) Writing a human Y chromosome (from scratch) (20:48) What if you could eliminate viral disease? (22:51) De-extinction and reinstating lost traits and genes (27:06) The Vertebrate Genomes Project (29:47) AlphaFold and other AI tools (41:27) CRISPR vs. Base Editing (emerging tools of genetic engineering) (49:40) Why multiplex editing will change the world (52:18) Molecular flight recorder (53:31) Preventing viral spillover and enhancing livestock (57:40) PCSK9 gene therapy for cholesterol (1:00:30) Is aging an evolved program? (1:05:21) Treating aging with a combination gene treatment (1:09:04) Does animal research help us understand human aging? (1:11:40) Human organoids as a model and therapeutic (1:13:34) Could engineered transplant organs become better than the originals? (1:16:17) Embryo editing controversy (1:28:41) Gene editing for space travel (1:30:40) Can synthetic biology alleviate poverty? (1:34:07) Is in vitro fertilization and embryo selection practically similar to editing? (1:39:12) The occasional cost of brilliance (1:45:45) Eradicating disease with Gene Drive (1:48:55) Technologies to solve Lyme disease (1:51:57) Dr. Church's experience with narcolepsy as a bridge to creative insights (2:00:42) Why George encoded his book in DNA Watch this episode on YouTube Show notes are available by clicking here Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/premium Learn more about the premium podcast The Aliquot: https://www.foundmyfitness.com/aliquot