In this episode of EBRC In Translation, hosts Heidi Klumpe and Talia Jacobson interview Sam Schaffter, lead scientist for RNA synthetic biology at the National Institute of Standards and Technology (NIST), about genetically encoded RNA circuits for real-time sensing of gene expression and their potential in diagnostics, therapeutics, and biotechnology. Sam describes his path from bioengineering and biochemistry at Purdue through DNA computing and molecular programming, to shifting toward cell...

In this episode of EBRC In Translation, Talia Jacobson and Will Grubbe interview Jim Collins of MIT, a pioneer of synthetic biology. He reflects on his path from human biomechanics and early gene circuit design to AI-driven antibiotic discovery. Collins discusses how deep learning is enabling new antibiotics despite market challenges, what makes research translation succeed, and the growing role of computation in biology. He also recounts developing RNA diagnostics and early CRISPR-based plat...

In this episode of EBRC In Translation, we are joined with Danielle Tullman-Ercek, a professor of chemical and biological engineering at Northwestern University and co-director of its Center for Synthetic Biology. Danielle discusses her journey from aspiring architect to leading bioengineer, the foundation and goals of her lab, the interdisciplinary approach at Northwestern's Center for Synthetic Biology, and the inception of her company, Opera Bioscience. She also shares insights on navigati...

In this episode of EBRC in Translation, we speak with Jenn Brophy, an assistant professor of Bioengineering at Stanford University. Jenn discusses her journey into plant synthetic biology, including how she transitioned from microbial synthetic biology and her motivation to increase female representation in academia. The conversation explores the current research directions of the Brophy lab, the technical and regulatory challenges in engineering plants versus bacteria, and the potential futu...

In this episode, we chat with Niko McCarty—a scientist turned writer who is the founding editor of Asimov Press and head of creative at Asimov. Niko takes us through his unexpected journey from biochemistry research to science journalism. He shares insights on transitioning from the lab to the press, crafting deep-dive narratives, and even pioneering projects like a book encoded in DNA. Whether you’re a scientist looking to sharpen your writing or simply curious about the art of storytelling ...

In this episode, we’re joined by Prof. Jef Boeke, a pioneer in synthetic genomics. Jef shares his journey from uncovering retrotransposons in yeast to leading the ambitious Sc2.0 project, an international collaboration to design and build the world’s first fully synthetic Saccharomyces cerevisiae genome. Along the way, we delve into the groundbreaking science, the collaborative spirit of synthetic biology, and what it takes to push the boundaries of genomics. For more information about EBRC: ...

In this episode, we speak with Daniel Goodwin and Paul Reginato, the co-founders of Homeworld Collective, a non-profit working to support the social, intellectual, and funding infrastructure needed for climate biotech. Dan and Paul discuss the challenges in climate biotech, action-oriented optimism, their fast-grants program for climate research, how writing is a superpower, and so much more. Later this year, Homeworld Collective will open a Garden Grants call for proposals on research in bi...

In this episode, we speak with Janice Chen, co-founder and CTO of Mammoth Biosciences. From her PhD work in Jennifer Doudna's lab to co-founding a biotech startup, Dr. Chen discusses her journey of translating scientific discoveries into real-world applications. Learn about the development of CRISPR-based diagnostics, including a rapid COVID-19 test, and gain insights into the evolving landscape of gene editing therapeutics. Dr. Chen also offers valuable advice for scientists looking to bridg...

In this episode, we talk to Sebastian Cocioba, a self-taught, independent researcher who designs flowers and develops tools that lower the entry barrier for others to do biology research. We talk with Sebastian about his unique path to Engineering Biology, his experience with DIY biology, the importance of open science, the role of citizen scientists in engineering biology, and much more! During the episode, Sebastian mentions that he recently started a YouTube channel, which you can find h...

In this episode, we interview Dr. Prachee Avasthi, Co-founder and CSO of Arcadia Science and previous Associate Professor of Biochemistry and Cell Biology at Dartmouth. We talk with Prachee about her many layers of experiments, from mining new biological tools to building new organizational structures for open science. We also talk with her about non-canonical career paths, science publishing models, and much more! For more information about EBRC: Visit our website at ebrc.org. If you are int...