Join us for a fascinating conversation with Dr. Martin Gurvey, DC. We discuss the philosophy of evidence-based medicine, vitalism, and how the two interact and/or bifurcate within our professions. Become a member and learn more at https://drjournalclub.com/Logan AC, Goldenberg JZ, Guiltinan J, Seely D, Katz DL. North American naturopathic medicine in the 21st century: Time for a seventh guiding principle - Scientia Critica. Explore (NY). 2018 Sep;14(5):367-372. doi: 10.1016/j.explore.2018.03.009. Epub 2018 Aug 2. PMID: 30217641.Use of Complementary and Integrative Approaches: Avoiding Irrational Dichotomieshttps://www.nwrpca.org/news/616940/Use-of-Complementary-and-Integrative-Approaches-Avoiding-Irrational-Dichotomies.htm

Happy birthday Adam! Join us for this special birthday Pod where we discuss a fascinating new meta-analysis on the association of PPIs and Dementia. Learn about the study's results, methods, a rabbit hole about prediction intervals, and Adam's Tupperware approach to confidence intervals.  Learn more and become a member on https://drjournalclub.com/PPIs and Barrett's Continuing Education Course: https://drjournalclub.com/continuing-education/Ahn N, Nolde M, Krause E, Güntner F, Günter A, Tauscher M, Gerlach R, Meisinger C, Linseisen J, Baumeister SE, Rückert-Eheberg IM. Do proton pump inhibitors increase the risk of dementia? A systematic review, meta-analysis and bias analysis. Br J Clin Pharmacol. 2023 Feb;89(2):602-616. doi: 10.1111/bcp.15583. Epub 2022 Nov 23. PMID: 36331350.Kumar R, Kumar A, Nordberg A, Långström B, Darreh-Shori T. Proton pump inhibitors act with unprecedented potencies as inhibitors of the acetylcholine biosynthesizing enzyme-A plausible missing link for their association with incidence of dementia. Alzheimers Dement. 2020 Jul;16(7):1031-1042. doi: 10.1002/alz.12113. Epub 2020 May 8. PMID: 32383816.Riley RD, Higgins JP, Deeks JJ. Interpretation of random effects meta-analyses. BMJ. 2011 Feb 10;342:d549. doi: 10.1136/bmj.d549. PMID: 21310794.IntHout J, Ioannidis JP, Rovers MM, Goeman JJ. Plea for routinely presenting prediction intervals in meta-analysis. BMJ Open. 2016 Jul 12;6(7):e010247. doi: 10.1136/bmjopen-2015-010247. PMID: 27406637; PMCID: PMC4947751.

Join us as we discuss a randomized controlled trial on the use of glutamine for post-infectious IBS. Very clinically useful information! We also discuss Adam's move and Josh's struggles with the start of the kiddos' school year. Learn more, subscribe, and browse our continuing education courses on https://drjournalclub.com/Zhou Q, Verne ML, Fields JZ, Lefante JJ, Basra S, Salameh H, Verne GN. Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome. Gut. 2019 Jun;68(6):996-1002. doi: 10.1136/gutjnl-2017-315136. Epub 2018 Aug 14. PMID: 30108163; PMCID: PMC9549483.

Join us as we discuss med shaming as well as diving into the recent results of the MIND trial, which looked at a specific dietary intervention in people at risk for developing dementia. Become a member at https://drjournalclub.com/Check out our continuing education catalog: https://drjournalclub.com/continuing-education/Barnes LL, Dhana K, Liu X, Carey VJ, Ventrelle J, Johnson K, Hollings CS, Bishop L, Laranjo N, Stubbs BJ, Reilly X, Agarwal P, Zhang S, Grodstein F, Tangney CC, Holland TM, Aggarwal NT, Arfanakis K, Morris MC, Sacks FM. Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons. N Engl J Med. 2023 Jul 18. doi: 10.1056/NEJMoa2302368. Epub ahead of print. PMID: 37466280.

Join us for this super speedy summary of the Nordic Maintenance Care study looking at the effectiveness and cost of a symptom-driven versus a maintenance approach to chiropractic care. Learn more and become a member on www.DrJournalClub.com Check out our EBM Bootcamp CourseEklund A, Jensen I, Lohela-Karlsson M, Hagberg J, Leboeuf-Yde C, Kongsted A, Bodin L, Axén I. The Nordic Maintenance Care program: Effectiveness of chiropractic maintenance care versus symptom-guided treatment for recurrent and persistent low back pain-A pragmatic randomized controlled trial. PLoS One. 2018 Sep 12;13(9):e0203029. doi: 10.1371/journal.pone.0203029. PMID: 30208070; PMCID: PMC6135505.

Join us on the pod, where we discuss a recent CNN article suggesting long-standing negative side effects with semaglutide. We discuss this, a high-quality network meta-analysis on this and other weight loss drugs for diabetics, and what being an evidence-based provider means. Learn more and become a member at www.DrJournalClub.comCritical Evaluation of the Medical Literature BootcampThe CNN articleThe BMJ Study The commentary on staying curious as a clinician. 

Josh and Adam discuss the new NEJM study on the use of Testosterone in men at high risk for cardiovascular events.  Learn more on www.DrJournalClub.com Check out our Critical Evaluation of the Literature Bootcamp Course. Lincoff AM, Bhasin S, Flevaris P, Mitchell LM, Basaria S, Boden WE, Cunningham GR, Granger CB, Khera M, Thompson IM Jr, Wang Q, Wolski K, Davey D, Kalahasti V, Khan N, Miller MG, Snabes MC, Chan A, Dubcenco E, Li X, Yi T, Huang B, Pencina KM, Travison TG, Nissen SE; TRAVERSE Study Investigators. Cardiovascular Safety of Testosterone-Replacement Therapy. N Engl J Med. 2023 Jul 13;389(2):107-117. doi: 10.1056/NEJMoa2215025. Epub 2023 Jun 16. PMID: 37326322.

Join us for this super speedy review of a recent study on the benefits and harms of treatments for chronic nonspecific low back pain without radiculopathy. We review the below study: https://pubmed.ncbi.nlm.nih.gov/36400393/Feise RJ, Mathieson S, Kessler RS, Witenko C, Zaina F, Brown BT. Benefits and harms of treatments for chronic nonspecific low back pain without radiculopathy: systematic review and meta-analysis. Spine J. 2023 May;23(5):629-641. doi: 10.1016/j.spinee.2022.11.003. Epub 2022 Nov 17. PMID: 36400393.Learn more on www.DrJournalClub.comTake our Evidence-Based Medicine Bootcamp: https://drjournalclub.com/critical-evaluation-bootcamp/

Join us as we dissect a study on the association between laxative use and dementia. Become a member now: https://drjournalclub.com/More info: https://pubmed.ncbi.nlm.nih.gov/36870957/https://drjournalclub.com/propensity-scores/Feng J, Zheng N, Fan X, Li S, Jiang Y, Yi X, Yang H. Association of laxatives use with incident dementia and modifying effect of genetic susceptibility: a population-based cohort study with propensity score matching. BMC Geriatr. 2023 Mar 4;23(1):122. doi: 10.1186/s12877-023-03854-w. PMID: 36870957; PMCID: PMC9985868.

Join us for a fascinating conversation with Dr. Riaz Qureshi. We talk about his latest commentary paper on Chat GPT and Systematic Reviews and have a broader conversation about how AI and Machine Learning is changing medicine and evidence synthesis in general. Qureshi, R., Shaughnessy, D., Gill, K.A.R. et al. Are ChatGPT and large language models “the answer” to bringing us closer to systematic review automation?. Syst Rev 12, 72 (2023). https://doi.org/10.1186/s13643-023-02243-zCacciamani, G.E., Chu, T.N., Sanford, D.I. et al. PRISMA AI reporting guidelines for systematic reviews and meta-analyses on AI in healthcare. Nat Med 29, 14–15 (2023). https://doi.org/10.1038/s41591-022-02139-wInternational Collaboration for the Automation of Systematic Reviewshttps://picoportal.org/https://drjournalclub.com/critical-evaluation-bootcamp/