Episode 22 of CRAMSURG - Clinical Reasearch Appraisal and Methodology for Surgical Trainees. The paper for discussion is Antibiotics as first-line alternative to appendicectomy in adult appendicitis: 90-day follow-up from a prospective, multicentre cohort study, BJS Sept 2021, the teaching topic is propensity score matching. Brought to you by CRAMSURG www.cramsurg.org.