On this bonus episode we answer a listener's question about antibiotic resistance arising from agriculture by diving into the story of colistin, an antibiotic that is used as a last resort treatment. When colistin resistance was first reported in animals and humans, the public health community was understandably panicked, prompting governments to take action to regulate its use. Transcripts and episode sources at acs.org/chainreaction

Chain Reaction links chemistry's past to its future, revealing how this ever‑evolving science shapes the world around us, from the materials we use every day to the environment that we depend on. Each episode brings fresh perspectives and personal stories from chemists, engineers, and other scientists, as well as historians who guide us through pivotal moments in chemistry’s history. Together, we’ll uncover chemistry’s surprising connections, explore its interdisciplinary impact, and see how past discoveries set off the breakthroughs of today and the future.&nbsp;Whether you’re a student, an experienced scientist, or simply curious, Chain Reaction will show you how chemistry fits into the bigger picture — and why it matters now more than ever.