References
Free Radical Biology and Medicine 2014. Volume 71, June.Pages 1-15
J Mol Endocrinol. 2020 Nov; 65(4): R77–R90. 
REDOX and Cholesterol metabolism lectures-Dr Guerra
 

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ImmunoEpigenetics65. 7-keto-cholesterol-induced miR-144 transcription inhibits IDH2 translation lowering NADPH required for NO synthesis to maintain endothelial function leading to atherosclerosis.

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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.

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ImmunoEpigenetics63. Amino acid metabolism is linked to DNA methylation via glycolytic intermediates and redox poise to expose neomorphic /antimorphic IDH1/2 transformation generating oncometabolites

ImmunoEpigenetics64. IDH1/2 ad Malic enzymes 1/2/3 may generate NADPH thus driving removal of ROS while simultaneously promoting atherosclerosis and tumorigenesis via epigenetic and bioenergetic means