References
Cancers (Basel). 2019 May; 11(5): 678. 
Oncogene.2017 Mar 23; 36(12): 1607–1618
Dr Guerra&#39;s annotated lecture notes from graduate biochemistry course(s)

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ImmunoEpigenetics64. IDH1/2 ad Malic enzymes 1/2/3 may generate NADPH thus driving removal of ROS while simultaneously promoting atherosclerosis and tumorigenesis via epigenetic and bioenergetic means

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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.

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ImmunoEpigenetics62.Macrophage "training" and T cell activation are epigentically controlled by moonlighting glycolytic and amino acid metabolic enzymes generating enantiomers of 2-OH glutarate.DJGPhD

ImmunoEpigenetics63. Amino acid metabolism is linked to DNA methylation via glycolytic intermediates and redox poise to expose neomorphic /antimorphic IDH1/2 transformation generating oncometabolites