
Dr. William Horan (Bristol Myers Squibb) joins AJP Audio to discuss a newly approved, novel treatment for schizophrenia spectrum disorder, which has potential impacts for cognition in patients. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context. 00:45 Horan interview 03:15 Novel mechanism of action in the treatment of schizophrenia 05:39 Side effect profiles 07:20 Clinical impacts 08:31 The need for further investigation 09:58 Limitations 11:05 Further research 13:08 Kalin interview 13:21 Horan et al. 17:34 Levenstein et al. 19:00 Fountoulakis et al. 20:57 Couture et al. 23:18 Stern et al. 27:35 McGirr et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Mar 1, 2025
32 min

Dr. Andrea King (University of Chicago Medicine) joins AJP Audio to discuss a novel, real time assessment of the reward, stimulation, and negative affect of alcohol use in people with alcohol use disorder with and without depressive disorders. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the February issue, which focuses closely on issues surrounding addiction. 00:35 King interview 00:45 Allostatic model of addiction 02:12 Gathering data and the groups studied 07:37 The ethics of studying alcohol use in patients with AUD 10:38 Findings 13:29 The impacts of alcohol’s pleasurable effects on people with AUD and those without 14:32 Limitations of natural environment research versus laboratory research 18:18 Clinical implications 20:09 Further research 22:56 Kalin interview 23:03 King et al. 26:21 Brand et al. 28:12 Conway et al. 32:17 Kypriotakis et al. 35:42 Kuhn et al. 39:37 Grilo et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Feb 1, 2025
44 min

Dr. Charles Nemeroff (University of Texas at Austin) joins AJP Editor-in-Chief Dr. Ned Kalin to discuss the January issue of the American Journal of Psychiatry. Dr. Nemeroff is a guest editor of the special issue, which takes a close look at the potential, pitfalls, and clinicial implications of psychedelics in mental health treatment. 00:38 Nemeroff interview 02:27 McIntyre et al. 04:06 Ramaekers et al. 05:44 Ghaznavi et al. 08:01 Fonzo et al. 09:17 Wolfgang et al. 10:45 Psychedelics and psychotherapies 12:31 Aaronson et al. 14:17 Pagni et al. 15:31 Kirlić et al. 17:06 Olson Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Jan 1, 2025
19 min

Devon Grey and David Knight (University of Alabama, Birmingham) join AJP Audio to discuss how exposure to discrimination impacts neural reactivity to stress and psychological distress in adolescents. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins us to discuss the rest of the December issue of AJP. 00:36 Grey and Knight interview 02:41 Demographics of the cohort 03:46 Neurobiological mechanisms of discrimination impacts 06:14 Racial discrimination and mental health impacts 09:34 Discrimination as a chronic stressor and prolonged activation of the stress response system 10:45 Limitations 13:52 Further research 14:38 Kalin interview 14:52 Grey et al. 17:35 Sippel et al. 18:06 Fox and Shackman 19:42 Kliemann et al. 22:16 Kamboj et al. 27:07 Pathak et al. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Dec 1, 2024
29 min

Dr. Phuc Le (Cleveland Clinic, Case Western Reserve University, Cleveland) joins AJP Audio to discuss racial, ethnic, and sociodemographic disparities in treatment in alcohol use disorder among participants of the All of Us cohort. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins to discuss the rest of the November issue, which takes a close look at issues surrounding substance use disorders. 00:41 Le interview 01:52 Disparities in treatment of AUDs in the US 03:43 What is the VA system doing right? 05:25 All of Us 06:39 Immediate clinical implications 08:15 Limitations 09:38 Further research 10:55 Kalin interview 11:07 Le et al. 13:44 Imperio et al. 14:43 McClure et al. 17:23 Perlman et al. 20:57 Savage et al. 24:17 Compton et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Nov 1, 2024
27 min

Dr. Bodyl Brand (Oxford University, UK) joins AJP Audio to discuss the effectiveness of menopausal hormone therapy in preventing psychosis relapse in women with schizophrenia and schizoaffective disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin takes us through the rest of the October issue of the American Journal of Psychiatry, which focuses on other issues touching psychosis and schizophrenia spectrum disorders. 01:05 Brand interview 03:08 MHT and potential side effects in schizophrenia treatment 06:16 Estrogen and psychosis prophylaxis 07:44 MHT effectiveness 10:15 Clinical implications 11:27 Strengths and limitations 13:47 The need for further study 15:54 Further research 17:24 Kalin interview 17:47 Brand et al. 20:17 Partanen et al. 23:54 Moran et al. 26:48 Gallucci et al. 30:38 Arion et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Oct 1, 2024
36 min

Dr. Jessica Salvatore (Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey) joins AJP Audio to discuss peer social genetic effects and their impact on alcohol and substance use, anxiety, and major depressive disorders in adolescents. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin takes us through the rest of the September issue of the American Journal of Psychiatry. 00:52 Salvatore interview 02:49 Can the genetic makeup of other people impact your risk for psychiatric conditions? 04:12 Impact on genetic predisposition 05:12 Why look at these effects through a genetic lens? 07:17 Limitations 10:05 Clinical implications 12:40 Further research 13:32 Kalin interview 13:47 Salvatore et al. 15:54 Dalhuisen et al. 19:23 Hess et al. 24:14 Larsen et al. 26:43 Schwippel et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Sep 1, 2024
30 min

Dr. Evan Krueger (Tulane University School of Social Work) joins AJP Audio to discuss the impact of sexual identity change and continuity on the mental health and substance use of adults who identify as a sexual minority. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the August issue of AJP. 00:52 Krueger interview 02:49 The Generations Study 04:21 How the sample differed 05:42 Differences between male and female, monosexual and plurisexual 07:53 Clinical implications for this population 09:39 Limitations 11:11 Life course and societal changes as potential factors? 13:05 Further research 14:31 Kalin interview 14:37 Krueger et al. 17:21 Amstadter et al. 20:45 Hilbert et al. 23:13 Bommersbach et al. 25:49 Zhou et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Aug 1, 2024
29 min

Dr. Lina Jonsson (Sahlgrenska Academy at University of Gothenburg, Sweden) joins AJP Audio to discuss the association of occupational dysfunction and hospital admissions with polygenic profiles in patients with bipolar disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the July issue of AJP. 00:45 Jonsson interview 04:35 Occupational dysfunction and hospitalization in bipolar disorder 05:29 Crossover between groups in patients with schizophrenia spectrum disorder 06:37 Clinical implications for working with patients with bipolar disorder 07:46 Limitations 09:03 Future research 10:14 Kalin interview 10:31 Jonsson et al. 13:43 Baum et al. 15:00 Kang et al. 18:10 Rohde et al. 22:06 Ironside et al. 26:30 Chen et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Jul 1, 2024
31 min

Ms. Sara Tramazzo (Stony Brook University) joins AJP Audio to discuss the long-term outlook for patients with schizophrenia spectrum disorders and other psychotic disorders over the course of 25 years. Afterwards, Dr. Ned Kalin joins to discuss the rest of the June issue of AJP. 00:50 Tramazzo interview 01:55 Lower levels of recovery and remission than other long-term studies 03:01 Difficulties of following patients in long-term studies 04:35 Differences between recovery and remission 05:54 Clinical implications 07:49 Limitations 10:21 Follow up periods 11:17 Further research 12:39 Kalin interview 12:53 Tramazzo et al. 15:51 Erwin et al. 18:59 Van der Pluijm et al. 20:47 Vita et al. 23:08 Tamon et al. 25:06 Norman et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at [email protected]
Jun 1, 2024
29 min
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