BIODorothea Koh is the founder and CEO of a healthcare technology company, Bot MD. Bot MD is a mobile-based AI chatbot that provides an interface for doctors to quickly access information related to hospital policies, formularies, check who’s on call etc. Along with her founder YC, Dorothea started Bot MD back in 2018 and joined Y Combinator’s summer 2018 batch. Prior to starting Bot MD, Dorothea rocketed up through the ranks at Medtronic and then Baxter, eventually holding the portfolios of country head for Singapore, Indonesia, Philippines, Brunei and Myanmar. However, she chose to give that up and chose the unconventional path, resigning from her job to start Bot MD.3 THINGS I LEARNEDIt hurts to “wander around in the desert” looking for product market fit, but it’s an unavoidable part of the journey and it teaches you a lot of lessons. Trust your instincts as an entrepreneur. Keep iterating until you have something that customers snatch out of your hands, maybe even before it’s perfect.Think twice before raising funds. Dorothea thinks of it like credit card debt - you can draw down as much as you want on it, but there’s a hefty interest bill to come later. Do as much as you can to stretch your funds. If your idea isn’t working, think about shutting the firm down rather than raising more money to keep a zombie company going.It’s important for leaders to be on the ground, so that you know exactly what your customers want. Dorothea used to make her sales reps take her to the deepest parts of China with them to meet her customers. TOPICS WE COVEREDWhat life was like at Y Combinator, and how it differs from the Stanford Biodesign courseWhat it was like pitching to her seed investors - and what seed investors are looking forWhat it feels like to “wander in the desert” looking for product market fitHow you know you have product market fitHow you should think about raising funds for your startup - it’s not a free lunchWhat Dorothea learned from working for established medical technology companiesHow Dorothea went to see the users of her company’s products in far flung villages - and the lessons this taught herSkills you should focus on learning when you are working for other larger organisationsWhat’s next for Bot MD

BIODorothea is the founder and CEO of a healthcare technology company, Bot MD. Bot MD is a mobile-based AI chatbot that provides an interface for doctors to quickly access information related to hospital policies, formularies, check who’s on call etc. Along with her founder YC, Dorothea started Bot MD back in 2018 and joined Y Combinator’s summer 2018 batch. Prior to starting Bot MD, Dorothea rocketed up through the ranks at Medtronic and then Baxter, eventually holding the portfolios of country head for Singapore, Indonesia, Philippines, Brunei and Myanmar. However, she chose to give that up and chose the unconventional path, resigning from her job to start Bot MD.3 THINGS I LEARNEDChoosing a co-founder is one of the most important steps. In Dorothea’s words, it’s like being married and raising a baby together with your partner. Only you and your co-founder fully understand “how sucky it is when times are down”. It’s during these times that your co-founder might be vital in providing you with encouragement.Start by building low-code prototypes. These are prototypes that involve little to no code. The goal is to prove certain hypotheses before you get too caught up with building the prototype.A startup journey might take 10 years of your life, with lots of stress and sleepless nights. So you need to ask yourself whether your idea is worth the pain of going through that process. Do people want it enough? What is your right to win, and why should you be building it? What’s the size of the market?TOPICS WE COVEREDWhat Bot MD doesWhy Dorothea left her first job at EDBThe initial experiment Dorothea ran that made her realise that Bot MD was a good ideaWhy building a startup is a painful journey but a very instructive oneThe importance of having a co-founderWhat a cofounder relationship is likeWhat Dorothea does as CEOFactors to consider when starting a startupDorothea’s epiphany that turned the company around and helped them find product market fitBot MD’s breakthrough product in NUH

Dr Daniel Ting is the Consultant, Vitreo-retinal surgeon in the Singapore National Eye Center (SNEC), Head of AI and Digital Innovation in the Singapore Eye Research Institute (SERI), and an Associate Professor in Ophthalmology with Duke-NUS Medical School Singapore. He is also the visiting Full Professor in Ophthalmology in Zhongshan Ophthalmic Eye Center, Sun Yat-Sen University, China; 2017-2018 US-ASEAN J. W. Fulbright Scholar to Johns Hopkins University, the EXCO of the American Academy Ophthalmology (AAO) AI Task Force and Standards for Reporting of Diagnostic Studies (STARD-AI) Task Force. At present, he is the Associate Editor of Nature Digital Medicine, Section Editor (AI and big data) in British Journal of Ophthalmology (BJO) and the Editor of Ophthalmology, Ophthalmology Retina, Ophthalmology Science and Asia-pacific Journal of Ophthalmology.To date, he has published >180 peer-reviewed papers/book chapters/conference abstracts, including >40 AI and digital technology articles in JAMA, NEJM, Nature Medicine, Nature Digital Medicine, Lancet Digital Health and others. Daniel holds several patents in deep learning systems for medical imaging analysis, and is also the co-founder of an AI spin-off company, EyRIS Pte Ltd. EyRIS has commercialised the Singapore Eye Lesion Analyser and to date has partnered with >20 optometry practices.3 THINGS I LEARNEDPerseverance is a fundamental ingredient for success. Dr Ting’s initial work was rejected numerous times, but he never gave up. He kept persisting until it was finally accepted into a big journal (Journal of the American Medical Association) - which was the break he needed to launch his career.Mentors are important, both in terms of giving you advice to guide your career and opening door and providing opportunities for you to build new skills and competencies.If you want to learn new skills, you have to be ready to read a lot. Today this data is freely available on the internet. Apart from reading and listening to talks, you can also consider following the leading lights in the field on twitter for instance to get a feel for where the cutting edge developments are.

Dr Ngiam Kee Yuan is the Group Chief Technology Officer of the National University Health System (NUHS) Singapore overseeing technology deployment in Western Healthcare Cluster of Singapore. He is concurrently the Deputy Chief Medical Informatics Officer at the National University Hospital of Singapore and has a special focus on artificial intelligence research and implementation in healthcare. He has certification training by the American Medical Informatics Association and has published in computing and medical journals on topics related to healthcare AI applications and technology.Dr Ngiam is a Consultant Thyroid and Endocrine Surgeon and Assistant Professor at the Department of Surgery, National University Hospital, Singapore specializing in thyroid oncology and minimally invasive endoscopic and robotic thyroid surgery. Dr. Ngiam also engages in research into endocrine and metabolic surgery as well as artificial intelligence applications in healthcare.He promotes interdisciplinary collaboration throughout the NUS campus, particularly between the schools of medicine, engineering, and computer science for various healthcare applications. He has been awarded the ExxonMobil-NUS Research Fellowship for Clinicians and numerous teaching awards for his work in research and education.3 THINGS I LEARNEDTake a year out if you would like to explore an area that you want to go into. But be clear about what you want to explore and achieve. Keep in close contact with your mentor to ensure that you are not forgotten or lost. Speak to your employers to ensure that the additional skills you come back with are valued by the organisation and are rewarded accordingly. You don’t necessarily need to learn how to code to get started on a project - Dr Ngiam certainly did not know how to when he started. Instead crucially he surrounded himself with experts and became good at translating clinical questions into language computer scientists could understand. He picked up computer science concepts along the way - a much more practical way of learning.Interesting spaces to look at for the future: (1) Automation of basic mundane processes in healthcare (2) Amalgamating data and giving clinicians tools to build better models and improve patient care.THINGS WE TALKED ABOUTThe origins of Dr Ngiam’s interest in AI and machine learningHow it became apparent to him that a lot of the problems that he was facing in his own research projects were replicated across the entire organisationThe size of this problem and how Dr Ngiam set out to tackle itGathering a team and building a community to tackle this problemBeing the person who translated the needs of healthcare professionals into language that computer scientists could understand and problems they could addressAcquiring skill on the job is a better way of learningGetting senior management buy in and support for the projectOther opportunities, including Medilot, that opened upThe need for clinicians to do more than just their clinical practiceStarting a new track for clinician innovatorsDr Ngiam finding ways to fund his passion - with grant funding and then a job title that gave him time to build this aspect of his careerTaking a year out to pursue other interests and not getting lost along the wayInteresting technological advances that will reshape the future of medicine

Dr Deborah Wong is a mother, general practitioner, entrepreneur and fitness guru. Shortly after graduating from medical school, she took over a pilates studio (Breathe Pilates), turned it around and expanded it into a successful and highly profitable chain with 4 locations across Singapore. Breathe Pilates is unique in offering training programmes for pilates instructors in addition to standard pilates classes. Deborah maintains a professional interest in lifestyle medicine, and she has personally experimented with multiple training programmes, diets and supplements.3 THINGS I LEARNEDBefore you get into any diet, take your time to analyze exactly what you want to achieve and how the diet will help you achieve the goal. Also, for pregnant and nursing mums, they need to be extremely careful before getting into any fad diets.Working from home is never an excuse for you not to exercise. Set aside 15-30 minutes daily to take a walk, go for a jog, or some light exercises like squats. People have no idea what a walk a day can do for their health.Start with strength training. Strength training would build muscles which are more metabolically active, which means that your body will be burning more calories. It helps with cardiovascular health as well. And importantly, building muscles and being able to lift heavier weights is rewarding, encouraging you to persist with your exercise plan.TOPICS WE DISCUSSEDExercises for people who want to stay lean Deborah’s big picture approach to nutritionThoughts about fad dietsKeto diets and whether you should use themIntermittent fastingDeborah’s thoughts on supplementsExercises for people confined to their homesAdvice for young doctors starting their careersAdvice to people who are just starting their business

BIODr Deborah Wong is a mother, general practitioner, entrepreneur and fitness guru. Shortly after graduating from medical school, she took over a pilates studio (Breathe Pilates), turned it around and expanded it into a successful and highly profitable chain with 4 locations across Singapore. Breathe Pilates is unique in offering training programmes for pilates instructors in addition to standard pilates classes. Deborah maintains a professional interest in lifestyle medicine, and she has personally experimented with multiple training programmes, diets and supplements.3 THINGS I LEARNEDRaising capital: If you intend to venture into business, you need money. Many people have business ideas in their heads, and the only thing that hinders them is capital. Don’t be afraid to ask your family to chip in if they are capable of stepping in.  You don’t lose anything by trying.In entrepreneurship, you need to keep evolving and be innovative to remain in business, especially during pandemics. COVID has taught us things can change in a fortnight, and if you want your business to survive, you need to be strategic.When building your business, it is essential to ensure that you have structures and processes that don’t need you always to be there to make it successful. Build a business that can run without requiring your presence all the time.TOPICS WE COVEREDHow Deborah acquired the business and turned it aroundDeborah’s transition from doctor to entrepreneurHow Deborah learned what she needed to know about running the businessHow Deborah runs the pilates studio in terms of prioritising and making decisionsStrategies that Deborah and her partner adopted to deal with the challenges that came with Covid Why Deborah has hired a data scientistThe importance of having the right location in businessWhy Deborah decided to start training pilates instructorsGetting back into medicine after taking a break for a yearHow Deborah ended up practising medicine in ShanghaiBalancing full-time employment and running a business at the same timeThe benefits of autonomy and flexibility that being a business owner brings

In this masterclass with A/Prof Ong, we discuss the fundamentals of leadership and mentorship.BIOA/Prof Ong Biauw Chi is Senior Consultant at Singapore General Hospital Department of Anaesthesiology. She was the Head of Anaesthesiology, SGH from 2009 till 2014 and the Director of Patient Safety and Director of Clinical Governance in Singapore General Hospital for a period of 9 years. She is also appointed Chairman Medical Board, Sengkang Health.A/Prof Ong’s work has been recognised with the Public Administration Silver Medal in the National Day Awards, 2013 and the National Medical Excellence award for National Outstanding Clinical Quality Activist in 2014.A/Prof Ong is also a member of the Specialist Training Committee for Anaesthesia (now Residency Advisory Committee) Ministry of Health, Singapore and chairs the Examinations committee for Anaesthesia Examinations in Singapore.3 THINGS I LEARNEDYou need to find the correct partners. In your career, you need to get the right people who will help you get better. People who will tell as it is and help you to remain focused on your goals.Planning: I learned a lot from Prof Ong’s willingness to take the time to step back and look at the bigger picture of what she wanted to achieve. This was a habit built from an early age. She uses a short-term, middle-term, and long-term list. The short-term list is cleared daily. The medium-term list focuses approximately a month out whilst the long-term list is reviewed six monthly and charts her overall life direction and goals. There’s no one right way to be a mentor. Instead it’s about spending time talking to your mentee, figuring out what makes them tick and pointing them in the right direction from there.

In this episode, A/Prof Ong Biauw Chi and I discuss her on-the-ground style of leadership and the journey she took to become Chairman of the Medical Board in Sengkang Health.ABOUT A/PROF ONGA/Prof Ong Biauw Chi is Senior Consultant at Singapore General Hospital Department of Anaesthesiology. She was the Head of Anaesthesiology, SGH from 2009 till 2014 and the Director of Patient Safety and Director of Clinical Governance in Singapore General Hospital for a period of 9 years. She is also appointed Chairman Medical Board, Sengkang Health.A/Prof Ong’s work has been recognised with the Public Administration Silver Medal in the National Day Awards, 2013 and the National Medical Excellence award for National Outstanding Clinical Quality Activist in 2014.Prof Ong is also a member of the Specialist Training Committee for Anaesthesia (now Residency Advisory Committee) Ministry of Health, Singapore and chairs the Examinations committee for Anaesthesia Examinations in Singapore.3 THINGS I LEARNEDLeadership is not always sitting in the boardroom and attending meetings. It involves going to the ground and seeing the truth for yourself. Sometimes it is difficult to know what’s really happening on the ground unless you are personally there. As a leader, you need to go see how things are on the ground.So, how do you know when you need to go down to the ground to check things out for yourself? That’s where experience comes in - it gives you a gut feel for when something doesn’t quite fit, or when your presence as a leader might be needed.Passion and curiosity: When you are passionate about what you do, you give it your all and become the best you can be. Curiosity goes hand in hand with passion. If you are passionate about something, you’ll always want to go the extra mile and learn more. Curiosity compliments passion.

In this episode, Dinesh gives a masterclass on raising angel investment for your startup. He also shares his perspective as an investor on how he evaluates founders and companies who have approached him for investment.BIODr. Dinesh is a practicing medical doctor and scientist. He completed medical training at the National University of Singapore, during which he received the Wong Hock Boon Society for Research Distinction award - he has since published over 30 manuscripts in peer-reviewed journals including Lancet Diabetes & Endocrinology, JAMA Ophthalmology, and IOVS, and is an active reviewer in journals including JAMA Ophthalmology. He is best known for his work as Head (Health Informatics) 2011-2019 in the Collaborative Ocular Tuberculosis Study group, a project that spanned 10 years and used big data to address ocular tuberculosis, where Dinesh oversaw the collaboration of 25 hospitals across 10 countries.Dinesh has also co-founded Doctorbell, overseeing product strategy and medical affairs. His startup was acquired in 2018 by MaNaDr, MOH telemedicine sandbox. He currently provides independent consulting in health technology and invests in digital health start-ups such as AskDr. 3 THINGS I LEARNEDAt the seed stage, it is possible to raise money from grants and competition prizes - it’s worth checking these out. If you would like to meet angel investors, one possible way is to take your idea to hackathons or accelerator programmes. Not only do these connect you to the right people, they’re also structured in such a way as to help you think through your idea.Pick your angel investors carefully. The individual  has to regularly meet, comment, and contribute to the strategy overall running of the company. If this person doesn't have the right expertise, background, and knowledge, they could be a huge drag.When raising money: Raise more than you need, and don’t forget that you need time to raise your next funding round. But also raise at a fair valuation - you can have subsequent rounds of funding that gives up less equity when your product is more proven and has taken some risks off the table.

I talk to Dr Dinesh Gunesekaran about his experience getting involved in a research project that used big data to gain insights into tuberculosis infections of the eye. From there, Dinesh got approached at a medical conference by his cofounders who wanted to start a telemedicine company. Dinesh shares his story about building his company, Doctorbell, and eventually selling it in 2018.BIODr. Dinesh is a practicing medical doctor and scientist. He completed medical training at the National University of Singapore, during which he received the Wong Hock Boon Society for Research Distinction award - he has since published over 30 manuscripts in peer-reviewed journals including Lancet Diabetes & Endocrinology, JAMA Ophthalmology, and IOVS, and is an active reviewer in journals including JAMA Ophthalmology. He is best known for his work as Head (Health Informatics) 2011-2019 in the Collaborative Ocular Tuberculosis Study group, a project that spanned 10 years and used big data to address ocular tuberculosis, where Dinesh oversaw the collaboration of 25 hospitals across 10 countries.Dinesh has also co-founded Doctorbell, overseeing product strategy and medical affairs. His startup was acquired in 2018 by MaNaDr, MOH telemedicine sandbox. He currently provides independent consulting in health technology and invests in digital health start-ups such as AskDr. 3 THINGS I LEARNEDExpose yourself to opportunities: Dinesh’s entrepreneurial journey only started because he sought out an opportunity to do big data research in ophthalmology. That led him to cross paths with his cofounders at a conference. But more importantly, Dinesh worked hard to execute and complete the projects he was tasked with - which was why more and more opportunities landed in his lap.It pays to be active on LinkedIn. Whilst trying to build his network in the startup / entrepreneurship space, Dinesh leveraged his LinkedIn network to share articles, communicate his interests, connect with people and listen to their ideas. It made me think about paying more attention to my own LinkedIn profile.Much of Dinesh’s knowledge about building startups was self taught - he was averaging reading a book a week as he sought to develop the knowledge needed to grow the startup. Startup founders need to be masters of many fields - but pushed by necessity, it is possible to develop expertise in all of these domains.