The Proof with Simon Hill
The Proof with Simon Hill
Live better for longer
Biology of aging and tips to slow it down | Matt Kaeberlein, PhD
3 hour 4 minutes Posted Feb 27, 2023 at 7:28 pm.
Intro
Aging and disease
Evolutionary conserved processes and human life span
Biological aging: Are epigenetic tests more accurate in telling how well you’re aging?
Aging process and the burden of senescence cells
Keys to a longer, healthier life
Sleep and exercise
Calorie restriction, longevity, and prolonged fasting
Protein restriction and its implications
Plant protein vs animal protein
Natural occurring polyphenols and supplements related to longevity
Rapamycin and rapamycin derivatives
Anti-aging compounds
Ethical implications of prolonging the life
Outro
0:00
3:04:48
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Show notes
Episode #249. Have you ever wondered how long humans can healthily live for? Professor Matt Kaeberlain joins me in this episode to explain the biological processes of aging, explaining the significance of genetics vs lifestyle, protein restriction, polyphenols, and much more.Specifically, we discuss:
Intro (
00:00)
Aging and disease (
03:42)
Evolutionary conserved processes and human life span (
17:41)
Biological aging: Are epigenetic tests more accurate in telling how well you’re aging? (
26:29)
Aging process and the burden of senescence cells (
34:06)
Keys to a longer, healthier life (
45:08)
Sleep and exercise (
55:38)
Calorie restriction, longevity, and prolonged fasting (
1:15:23)
Protein restriction and its implications (
1:32:14)
Plant protein vs animal protein (
1:43:31)
Natural occurring polyphenols and supplements related to longevity (
1:53:06)
Rapamycin and rapamycin derivatives (
2:13:53)
Anti-aging compounds (
2:29:38)
Ethical implications of prolonging the life (
2:51:08)
Outro (
2:57:23)
To connect with Dr Matt Kaeberlein, you can find him on Twitter and LinkedIn. Head to his website, https://kaeberlein.org, to learn more about his work. If the Dog Aging Project interests you, you can visit the website or read this article in Nature. Keep up to date with Optispan here.Discover more insights and supporting resources in the full show notes.Enjoy, friends.SimonWant to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.Simon Hill, MSc, BSc (Hons)Creator of theproof.com and host of The Proof with Simon HillAuthor of The Proof is in the PlantsWatch the episodes on YouTube or listen on Apple/SpotifyConnect with me on Instagram, Twitter, and FacebookNourish your gut with my Plant-Based Ferments GuideDownload my complimentary two-week meal plan and high protein Plant Performance recipe book