From the authors of David Olvera, FP-C and Daniel Davis M.D. The abstract introduction: Rapid sequence intubation (RSI) is associated with a number of complications that can increase morbidity and mortality. Among RSI agents used to blunt awareness of the procedure and produce amnesia, ketamine is unique in its classification as a dissociative agent rather than a CNS depressant. Thus, ketamine should have a lower risk of peri-RSI hypotension due to the minimal sympatholysis as compared to other agents. The main goal of this analysis was to explore the incidence of hypotension and/or cardiopulmonary arrest in patients receiving ketamine versus other agents during RSI. We hypothesized that ketamine would be associated with a lower risk of hemodynamic complications, particularly after adjusting for co-variables reflecting patient acuity. In addition, we anticipated that an increased prevalence of ketamine use would be associated with a decreasing incidence of peri-RSI hypotension and/or arrest. We couldn’t make this podcast without. Please rate, and review wherever you download the podcast. Thanks for listening!