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March 21, 2008
Review for Final Exam: This class covers all topics discussed in the course, with an emphasis on cell signaling.
March 17, 2008
Lecture 28: The instructor reviews some major pathways dealing with signal transduction and an application of principles learned to cancerous cells.
March 14, 2008
Lecture 27: Kaplan continues his discussion of signal transduction, the role of signals in cell migration, and the ability of cells to see which direction to move.
March 12, 2008
Lecture 26: Kaplan talks about properties of signaling modules and different kinds of membrane receptors that interpret signals from outside the cell.
March 10, 2008
Lecture 25: This class is a wrap-up of cell division and checkpoints in the regulatory cycle, and introduction to how cells interpret various biochemical signals.
March 7, 2008
Lecture 24: Students learn more about cell division, and introduction to cell checkpoints along the regulatory cycle.
March 4, 2008
Review for Midterm 2: This covers protein trafficking, the cytoskeleton and cell division.
March 3, 2008
Lecture 22: This is a continued discussion of the regulation of cell division -- how mitosis is coordinated within the cell.
February 29, 2008
Lecture 21: The stages of the cell cycle, the regulatory cycle, and biochemical switches involved in these two cycles are covered.
February 27, 2008
Lecture 20: Kaplan wraps up of the cytoskeleton, relation of microtubles to cell motility, introduction to cell division.
February 25, 2008
Lecture 19: In this class, microtubule dynamics and stability and how these aspects of microtubules are controlled to produce energy and force for processes such as mitosis.
February 22, 2008
Lecture 18: In a continued discussion of intermediate filaments, Kaplan talks about their relation to other cytoskeletal filaments and microtubule dynamics.
February 20, 2008
Lecture 17: This class covers actin polymerization, and an introduction to other parts of the cytoskeleton, such as the intermediate filaments.
February 15, 2008
Lecture 16: Kaplan continues talking about actin, how it can lead to cell motility, as well as how it and other filament dynamics are regulated within the cell.
February 13, 2008
Lecture 15: Kaplan discusses how cytoskeletal elements of a cell are involved in cell movement, such as actin.
February 10, 2008
Review for Midterm 1: This class covers cell biology techniques, cell compartmentalization, cell membranes, the secretory pathway and protein trafficking.
February 8, 2008
Lecture 14: The professor wraps up protein trafficking and non-secretory transport.
February 4, 2008
Lecture 12: Kaplan gives an in-depth discussion of in-vitro coupled translation and translocation.
February 1, 2008
Lecture 11: Kaplan reviews glycosylation and gives an in-depth look at the work done to understand protein translocation and examples of protein trafficking.
January 30, 2008
Lecture 10: In this continued discussion on protein translocation, Kaplan gives emphasis to glycosylation and the Scavenger pathway.
January 28, 2008
Lecture 09: Kaplan discusses the secretory pathway, with emphasis on protein targeting and translocation.
January 25, 2008
Lecture 08: Kaplan talks about how various proteins are directed to certain areas within the cell and to the plasma membrane.
January 23, 2008
Lecture 07: Kaplan discusses the various classes of membrane proteins and movement of molecules across the membrane.
January 18, 2008
Lecture 06: This is a continued discussion of cellular membranes and their various functions in biochemical reactions.
January 16, 2008
Lecture 05: This class wraps up of tools to study complex cellular behavior (including microscopy), and introduces membrane proteins.
January 14, 2008
Lecture 04: How to use subcellular fractionation and other techniques to study complex cellular processes and molecules.
January 11, 2008
Lecture 03: This class reviews what characteristics a gene needs to be "necessary and sufficient." A discussion of antibodies and their application to various techniques of cell biologists.
January 9, 2008
Lecture 02: Goals of cell biologists and the overall course plan are discussed and students introduced to the question of how to study cells.
January 7, 2008
Lecture 01: Kaplan discusses class mechanics, student questions and the central questions of cell biology.
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