Clopidogrel Pharmacology
Published July 4, 2019
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13 min
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    Clopidogrel is an antiplatelet agent that is often used in combination with aspirin to help reduce the risk of an MI.



    The risk of bleed is a high priority with the use of clopidogrel. Patients must be monitored for signs and symptoms of bleeding and bruising.



    Clopidogrel is a prodrug that is converted to its active metabolite by CYP2C19.



    Fluconazole can inhibit CYP2C19 which may reduce the effectiveness of clopidogrel.
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