In this episode, journalist Larry Tye talks about his new book, SHOCK, written with electroshock patient Kitty Dukakis, wife of former governor and presidential candidate Michael Dukakis. Following Tye, Charles Welch, director of the Massachusetts General Hospital electroconvulsive therapy program, discusses the treatments knowns and unknowns. Then Scientific American editor Christine Soares shares some insights about an unusual stem cell research conference held last week in New York City. Plus we'll test your knowledge of some recent science in the news. Websites mentioned on this episode include www.egrandslam.com; www.sciam.com/news; blog.sciam.com.