This episode was recorded May 22, 2020To claim credit visit: https://ce.mayo.edu/covid19podcast Guest: Gregory A. Poland, M.D. (@drgregpoland)Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) SARS-CoV-2, as an RNA virus, has marked capacity for mutation and recombination events. How do we build an efficacious and safe vaccine against it? How could we safely speed up development? Is a vaccine neutralizing the spike protein enough? Dr. Greg Poland returns to give you an update from the front lines of research on vaccine development and ongoing clinical trials.Dr. Poland’s Editorial:Tortoises, hares, and vaccines: A cautionary note for SARS-CoV-2 vaccine developmenthttps://doi.org/10.1016/j.vaccine.2020.04.073 'I Have A Dream' Speech, In Its Entiretyhttps://www.npr.org/2010/01/18/122701268/i-have-a-dream-speech-in-its-entiretyOur 'Fierce Urgency of Now' - Secretary Kathleen Sebeliushttps://obamawhitehouse.archives.gov/blog/2013/08/26/our-fierce-urgency-nowKing Legacy: 'Fierce Urgency of Now' Exists Today - Terri Moon Cronkhttps://www.defense.gov/Explore/Features/Story/Article/2059480/king-legacy-fierce-urgency-of-now-exists-today/AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.