Where does a medical cure come from? 100 years ago, it wasn't uncommon for scientists to test medicines by taking a dose themselves. As medical technologies get cheaper and more accessible, patients and DIY tinkerers are trying something similar—and mainstream medicine is racing to catch up. Prognosis explores the leading edge of medical advances, and asks who gets—or should get—access to them. We look at how innovation happens, when it fails, and what it means to the people with a disease trying to feel better, live longer, or avoid death.