In this two-part series, we look at the rise of artificial intelligence (AI) and examine the potential ways it may impact medicine. Our guest is Dr. Michael Victoroff, a family medicine physician, patient safety and risk management specialist, and clinical informatics expert who has gone down the rabbit hole of trying to understand the good, the bad, and the ugly of AI. Dr. Victoroff explains the fundamental technology behind AI applications, such as ChatGPT, and its interactive structure designed to generate human-like language and conversation. He talks about the concept of machine learning, how the “garbage in, garbage out” theory applies, and the “black box” dilemma of not knowing exactly how this technology got to its answers and what sources or information were used. We then look at the potential roles of AI in health care related to replacing scribes and documentation, voice recognition and language translation capabilities, and the ever-present concerns over accuracy and inadvertent errors that may arise.