Today on UpNext AI: OpenAI used its GPT-5.6 launch to signal that its models will remain central to Microsoft 365 Copilot, even as questions swirl about the companies’ evolving relationship. We also look at what OpenAI says is new in the broader GPT-5.6 family, a new clinical-reasoning paper for liver cancer treatment guidance, and three quick headlines on Google ad labeling, Meta’s unwound Manus deal, and OpenAI’s new long-running work tool.

Covered in this episode:
- OpenAI says GPT-5.6 is the preferred model for Microsoft 365 Copilot
- OpenAI launches the GPT-5.6 model family
- Research: HCC-STAR for hepatocellular carcinoma risk stratification and treatment guidance
- Google adds AI-made ad labels in My Ad Center
- Tencent leads a deal to unwind Meta’s $2 billion Manus acquisition
- OpenAI’s new ChatGPT Work / rebranded Codex push for longer-running workflows

Source links:
- https://techcrunch.com/2026/07/09/openai-says-gpt-5-6-is-the-preferred-model-for-microsoft-copilot-amid-breakup-chatter/
- https://techcrunch.com/2026/07/09/openai-launches-its-new-family-of-models-with-gpt-5-6/
- https://arxiv.org/abs/2607.08602v1
- https://www.theverge.com/ai-artificial-intelligence/963628/google-ai-generated-ads-label
- https://www.ft.com/content/0d04378d-d71b-4225-b31a-70504e358480
- https://arstechnica.com/ai/2026/07/openai-wants-its-new-tool-to-do-your-work-for-you-and-with-you/