Trying Not To Die
Trying Not To Die
Jack Osbourne
The Secret Illness That Changed Joe Manganiello's Life Forever
1 hour 24 minutes Posted Oct 27, 2026 at 10:00 am.
0:00
1:24:49
Download MP3
Show notes

Joe Manganiello joins Jack Osbourne on Trying Not To Die to reveal the mysterious illness that nearly killed him and why he kept his seven-year battle largely hidden from the public. After losing nearly 60 pounds and having his large intestine removed, Joe began a profound spiritual journey that took him through Santeria rituals, encounters with shamans, and a deeper exploration of his family history and ancestral trauma. Joe and Jack discuss generational curses, sobriety, the relationship between suffering and purpose, and how these experiences inspired Joe's new book, Bloodlines.

Thank you to our sponsors:

- For a limited time, save 20% on your first subscription order of AG1 Next Gen or AG1 Pro at https://DrinkAG1.com/TRYING.

- For a better way to stay hydrated, go to https://instanthydration.com/TRYING and use my promo code TRYING for over 40% off your first subscription order - it's Instant Hydration's best offer available.

- Go to https://TruNiagen.com and use promo code: TRYING for 20% off.