<img loading="lazy" class="alignleft wp-image-477 size-thumbnail" src="http://toxnow.org/wp-content/uploads/Green_Kratom_Leaf-150x150.jpg" alt="" width="150" height="150" srcset="http://toxnow.org/wp-content/uploads/Green_Kratom_Leaf-150x150.jpg 150w, http://toxnow.org/wp-content/uploads/Green_Kratom_Leaf-300x300.jpg 300w, http://toxnow.org/wp-content/uploads/Green_Kratom_Leaf-768x768.jpg 768w, http://toxnow.org/wp-content/uploads/Green_Kratom_Leaf-1024x1024.jpg 1024w" sizes="(max-width: 150px) 100vw, 150px" />
In this episode we talk to <a href="https://twitter.com/ToxInNewEngland" target="_blank" rel="noopener noreferrer">Ed Boyer</a> about Kratom, pharmacology, legal status, and discuss recent reports of adverse effects.
<ul>
<li>Boyer et al <a href="https://www.ncbi.nlm.nih.gov/pubmed/18482427" target="_blank" rel="noopener noreferrer">Self-treatment of opioid withdrawal using kratom (Mitragynia speciosa korth)</a></li>
<li><a href="https://www.fda.gov/NewsEvents/PublicHealthFocus/ucm584952.htm" target="_blank" rel="noopener noreferrer">FDA response to Kratom</a></li>
<li><a href="https://en.wikipedia.org/wiki/Bradford_Hill_criteria" target="_blank" rel="noopener noreferrer">Bradford Hill Criteria</a></li>
</ul>
Take Home Points:
<ul>
<li>Kratom is an opioid agonist</li>
<li>Patients should not mix Kratom with other substances</li>
<li>Patients at risk of seizures should not use Kratom</li>
<li>Kratom will not show up on a typical urine drug screen</li>
</ul>The post <a href="http://toxnow.org/archives/476">Episode 41 Kratom: Friend or Foe</a> first appeared on <a href="http://toxnow.org">ToxNow</a>.